IMMUNOSUPPRESSIVE EFFECTS OF FTY720 ALONE OR IN COMBINATION WITH CYCLOSPORINE AND/OR SIROLIMUS1

Cyclosporine

1989 • 1,340 citations

Improved technique of heart transplantation in rats

1969 • 1,338 citations

CYCLOSPORIN A IN PATIENTS RECEIVING RENAL ALLOGRAFTS FROM CADAVER DONORS

1978 • 1,010 citations

Orthotopic liver transplantation in the rat. Technique using cuff for portal vein anastomosis and biliary drainage.

1979 • 615 citations

ORTHOTOPIC LIVER TRANSPLANTATION IN THE RAT

1979 • 564 citations

Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite.

1994 • 532 citations

Transplantation of small bowel in the rat: technical and immunological considerations.

1971 • 376 citations

Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720

1995 • 306 citations

A NOVEL IMMUNOSUPPRESSANT, FTY720, WITH A UNIQUE MECHANISM OF ACTION, INDUCES LONG-TERM GRAFT ACCEPTANCE IN RAT AND DOG ALLOTRANSPLANTATION1

1996 • 291 citations

The side effect profile of sirolimus: A phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients

1996 • 267 citations

SYNERGISTIC INTERACTIONS OF CYCLOSPORINE AND RAPAMYCIN TO INHIBIT IMMUNE PERFORMANCES OF NORMAL HUMAN PERIPHERAL BLOOD LYMPHOCYTES IN VITRO

1991 • 205 citations

CAUSES OF GRAFT LOSS BEYOND TWO YEARS IN THE CYCLOSPORINE ERA

1990 • 146 citations

FTY720, a novel immunosuppressant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats.

1996 • 127 citations

Sirolimus: A new agent for clinical renal transplantation

1997 • 92 citations

EFFECTS OF THE PHARMACOKINETIC INTERACTION BETWEEN ORALLY ADMINISTERED SIROLIMUS AND CYCLOSPORINE ON THE SYNERGISTIC PROLONGATION OF HEART ALLOGRAFT SURVIVAL IN RATS1

1996 • 83 citations

FTY720, a novel immunosuppressant possessing unique mechanisms. II. Long-term graft survival induction in rat heterotopic cardiac allografts and synergistic effect in combination with cyclosporine A.

1996 • 71 citations

The synergistic effects of cyclosporine, sirolimus, and brequinar on heart allograft survival in mice.

1995 • 49 citations

FTY720, a novel immunosuppressant possessing unique mechanisms. III. Synergistic prolongation of canine renal allograft survival in combination with cyclosporine A.

1996 • 49 citations

Long-term graft acceptance in allografted rats and dogs by treatment with a novel immunosuppressant, FTY720.

1996 • 41 citations

The Synergistic Effects Of Cyclosporine, Sirolimus, And Brequinar On Heart Allograft Survival In Mice

1995 • 41 citations

FTY720, a novel immunosuppressant, possessing unique mechanisms. IV. Prevention of graft versus host reactions in rats.

1996 • 34 citations

Induction of lymphocyte apoptosis by a novel immunosuppressant FTY720: Relation with FAS, BCL-2 and BAX expression

1997 • 28 citations

FTY720, a novel immunosuppressive agent, enhances upregulation of the cell adhesion molecular ICAM-1 in TNF-a treated human umbilical vein endothelial cells

1997 • 26 citations

Deleted Work

1955 • 0 citations