Overexpression of miR‐210, a downstream target of HIF1α, causes centrosome amplification in renal carcinoma cells

MicroRNA signatures in human cancers

2006 • 7,358 citations

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene

1993 • 2,906 citations

Prognostic significance of morphologic parameters in renal cell carcinoma

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Campbell-Walsh urology

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Mutations of the VHL tumour suppressor gene in renal carcinoma

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Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.

1994 • 1,542 citations

A mechanism linking extra centrosomes to chromosomal instability

2009 • 1,368 citations

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

2010 • 1,149 citations

A MicroRNA Signature of Hypoxia

2006 • 1,043 citations

Emerging roles of E2Fs in cancer: an exit from cell cycle control

2009 • 922 citations

MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3

2008 • 874 citations

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

2009 • 835 citations

A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes

2006 • 715 citations

hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer

2008 • 647 citations

MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2

2009 • 611 citations

Centrosome amplification drives chromosomal instability in breast tumor development

2002 • 564 citations

Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival

2009 • 440 citations

MicroRNA Regulation of DNA Repair Gene Expression in Hypoxic Stress

2009 • 417 citations

MicroRNA-375 Is Downregulated in Gastric Carcinomas and Regulates Cell Survival by Targeting PDK1 and 14-3-3ζ

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E2F3 activity is regulated during the cell cycle and is required for the induction of S phase

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E2f3 is critical for normal cellular proliferation

2000 • 323 citations

MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU

2010 • 292 citations

Genome‐wide microRNA expression profiling in renal cell carcinoma: significant down‐regulation of miR‐141 and miR‐200c

2008 • 272 citations

hsa‐miR‐210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer

2010 • 240 citations

VHL mutations and their correlation with tumour cell proliferation, microvessel density, and patient prognosis in clear cell renal cell carcinoma

2001 • 218 citations

Renal cancer cells lacking hypoxia inducible factor (HIF)-1 expression maintain vascular endothelial growth factor expression through HIF-2

2006 • 153 citations

Carp, a Cardiac Ankyrin-Repeated Protein, and Its New Homologue, Arpp, Are Differentially Expressed in Heart, Skeletal Muscle, and Rhabdomyosarcomas

2002 • 79 citations

High‐resolution analysis of DNA copy number alterations and gene expression in renal clear cell carcinoma

2007 • 77 citations

Inactivation of E2F3 results in centrosome amplification

2003 • 73 citations

Centrosome abnormalities are frequently observed in non‐small‐cell lung cancer and are associated with aneuploidy and cyclin E overexpression

2006 • 68 citations

Analysis of the cellular centrosome in fine-needle aspirations of the breast

2007 • 59 citations

Novel treatments for metastatic renal cell carcinoma

2005 • 53 citations

Telomere shortening and mitotic dysfunction generate cytogenetic heterogeneity in a subgroup of renal cell carcinomas

2004 • 33 citations

Kidney Tumors in Adults

2004 • 11 citations

Centrosome amplification is correlated with ploidy divergence, but not with MYCN amplification, in neuroblastoma tumors

2008 • 6 citations