Anergy induced by thymic medullary epithelium

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

The Role of the T Cell Receptor in Positive and Negative Selection of Developing T Cells

1990 • 589 citations

T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views.

1980 • 574 citations

Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction

1991 • 523 citations

Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance

1990 • 380 citations

Self-Nonself Discrimination by T Cells

1990 • 331 citations

The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigens.

1983 • 280 citations

Identity of cells that imprint H–2-restricted T-cell specificity in the thymus

1986 • 267 citations

Thymic Epithelium Tolerizes for Histocompatibility Antigens

1990 • 179 citations

Tolerance Induced by Thymic Epithelial Grafts in Birds

1987 • 167 citations

Thymocytes appear to ignore class I major histocompatibility complex antigens expressed on thymus epithelial cells

1984 • 158 citations

An unusual lineage of alpha/beta T cells that contains autoreactive cells.

1991 • 152 citations

Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities.

1990 • 146 citations

STUDIES OF THE ROLE OF THE THYMIC ENVIRONMENT IN THE INDUCTION OF TOLERANCE TO MHC ANTIGENS

1985 • 127 citations

Tolerance in Transgenic Mice Expressing Major Histocompatibility Molecules Extrathymically on Pancreatic Cells

1990 • 117 citations

Non‐Deletional Mechanisms of Peripheral and Central Tolerance: Studies with Transgenic Mice with Tissue‐Specific Expression of a Foreign MHC Class I Antigen

1991 • 107 citations

Selective loss of HLA-A or HLA-B antigen expression in colon carcinoma.

1989 • 101 citations

T and B cell Tolerance and Responses to Viral Antigens in Transgenic Mice: Implications for the Pathogenesis of Autoimmune versus Immunopathological Disease

1991 • 97 citations

Enhancer elements directing cell-type-specific expression of cytokeratin genes and changes of the epithelial cytoskeleton by transfections of hybrid cytokeratin genes.

1989 • 97 citations

Immune responses of thymusf/ymphocyte embryonic chimeras: studies on tolerance and major histocompatibility complex restriction in Xenopus

1985 • 90 citations

Cytolytic T cells recognize the two amino-terminal domains of H-2 K antigens in tandem in influenza A infected cells

1984 • 82 citations

Tolerogenicity of thymic epithelium

1990 • 74 citations

Monoclonal antibodies against an H-2Kb-specific cytotoxic T cell clone detect several clone-specific molecules.

1986 • 61 citations

A Transgenic Approach to the Study of Peripheral T‐Cell Tolerance

1991 • 54 citations

Evidence for CD8-independent T cell maturation in transgenic mice.

1990 • 53 citations

Split tolerance induced by chick embryo thymic epithelium allografted to embryonic recipients.

1986 • 37 citations

Thymic epithelium tolerizes chickens to embryonic grafts of quail bursa of Fabricius

1989 • 33 citations

COMPARISON OF ALLOGENEIC AND XENOGENEIC DETERMINANTS ON THE H-2Kk MOLECULE

1983 • 27 citations

IMPAIRED REJECTION OF MINOR-HISTOCOMPATIBILITYANTIGEN–DISPARATE SKIN GRAFTS AND ACQUISITION OF TOLERANCE TO THYMUS DONOR ANTIGENS IN ALLOTHYMUS-IMPLANTED, THYMECTOMIZED XENOPUS

1986 • 18 citations

Induction of T cell differentiation in early-thymectomized Xenopus by grafting adult thymuses from either MHC-matched or from partially or totally MHC-mismatched donors.

1984 • 13 citations

Clonal elimination of self reactive V_β6⁺ T cells induced by H-2 products expressed on thymic radio-resistant components

1992 • 12 citations