Systems Biology and New Technologies Enable Predictive and Preventative Medicine

Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks

2003 • 41,909 citations

The Hallmarks of Cancer

2000 • 27,569 citations

Nanowire Nanosensors for Highly Sensitive and Selective Detection of Biological and Chemical Species

2001 • 5,712 citations

Systems Biology: A Brief Overview

2002 • 4,071 citations

Molecular imaging in living subjects: seeing fundamental biological processes in a new light

2003 • 2,194 citations

Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network

2001 • 2,058 citations

Translating Biomolecular Recognition into Nanomechanics

2000 • 1,636 citations

A Genomic Regulatory Network for Development

2002 • 1,538 citations

Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors

2003 • 1,422 citations

Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry

2003 • 1,371 citations

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays

2000 • 1,356 citations

Direct Ultrasensitive Electrical Detection of DNA and DNA Sequence Variations Using Nanowire Nanosensors

2003 • 1,297 citations

Control of Pancreas and Liver Gene Expression by HNF Transcription Factors

2004 • 1,293 citations

Molecular Imaging

2001 • 1,248 citations

Positron emission tomography provides molecular imaging of biological processes

2000 • 1,176 citations

Protein Nanoarrays Generated By Dip-Pen Nanolithography

2002 • 1,144 citations

Bioassay of prostate-specific antigen (PSA) using microcantilevers

2001 • 994 citations

Ultrahigh-Density Nanowire Lattices and Circuits

2003 • 879 citations

Serum Proteomic Patterns for Detection of Prostate Cancer

2002 • 758 citations

Biological Networks: The Tinkerer as an Engineer

2003 • 653 citations

Multiple label-free biodetection and quantitative DNA-binding assays on a nanomechanical cantilever array

2002 • 597 citations

An Integrated Microfabricated Cell Sorter

2002 • 511 citations

Sequence information can be obtained from single DNA molecules

2003 • 479 citations

Laser-capture microdissection: opening the microscopic frontier to molecular analysis

1998 • 464 citations

Boosted Decision Tree Analysis of Surface-enhanced Laser Desorption/Ionization Mass Spectral Serum Profiles Discriminates Prostate Cancer from Noncancer Patients

2002 • 438 citations

Label-free protein assay based on a nanomechanical cantilever array

2002 • 408 citations

Microchip Device for Cell Lysis, Multiplex PCR Amplification, and Electrophoretic Sizing

1998 • 404 citations

Molecular Imaging: Looking at Problems, Seeing Solutions

2003 • 382 citations

Microchip Device for Performing Enzyme Assays

1997 • 380 citations

Proteomic Patterns in Biological Fluids: Do They Represent the Future of Cancer Diagnostics?

2003 • 326 citations

Regulatory gene networks and the properties of the developmental process

2003 • 227 citations

Cell–cell interaction in prostate gene regulation and cytodifferentiation

1997 • 199 citations

Molecular imaging of gene therapy for cancer

2004 • 188 citations

Comparison of noninvasive fluorescent and bioluminescent small animal optical imaging

2003 • 157 citations

Laser capture microdissection and proteomics: Possibilities and limitation

2001 • 138 citations

Self-Sorting of White Blood Cells in a Lattice

1997 • 119 citations

Polymerase chain reaction microanalysis of tumors from stained histological slides.

1992 • 73 citations

Gene Expression Signatures, Cancer Cell Evolution and Metastatic Progression

2004 • 35 citations

Systems Approaches Applied to the Study of Saccharomyces cerevisiae and Halobacterium sp.

2003 • 12 citations

Micromachining Technology and Biosensors

1995 • 7 citations

Isolation of high quality mRNA from a discrete cell cycle population identified using a nonvital dye and fluorescence activated sorting

1993 • 7 citations

Class struggle: expression profiling and categorizing cancer

2003 • 6 citations