Sequence information can be obtained from single DNA molecules

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Initial sequencing and analysis of the human genome

2001 • 23,520 citations

The Sequence of the Human Genome

2001 • 13,500 citations

Fuzzy Nanoassemblies: Toward Layered Polymeric Multicomposites

1997 • 9,767 citations

Methods of Digital Video Microscopy for Colloidal Studies

1996 • 3,534 citations

Fluorescence Spectroscopy of Single Biomolecules

1999 • 2,015 citations

Fluorescence detection in automated DNA sequence analysis

1986 • 1,694 citations

Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution

1995 • 1,029 citations

Rapid nanopore discrimination between single polynucleotide molecules

2000 • 901 citations

Force and Velocity Measured for Single Molecules of RNA Polymerase

1998 • 892 citations

Sequence-specific detection of individual DNA strands using engineered nanopores

2001 • 734 citations

Single-Molecule Fluorescence Resonance Energy Transfer

2001 • 608 citations

Protein Diversity from Alternative Splicing

2000 • 548 citations

Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism

1999 • 515 citations

Single-molecule studies of the effect of template tension on T7 DNA polymerase activity

2000 • 484 citations

Human Whole-Genome Shotgun Sequencing

1997 • 320 citations

Replication by a single DNA polymerase of a stretched single-stranded DNA

2000 • 299 citations

Atomic-scale imaging of DNA using scanning tunnelling microscopy

1990 • 169 citations

Prediction of Gene Function by Genome-Scale Expression Analysis: Prostate Cancer-Associated Genes

1999 • 164 citations

Directly labeled DNA probes using fluorescent nucleotides with different length linkers

1994 • 136 citations

New DNA Sequencing Methods

2001 • 112 citations

Observation by fluorescence microscopy of transcription on single combed DNA

2002 • 97 citations

Fluorescence resonance energy transfer between single fluorophores attached to a coiled-coil protein in aqueous solution

1999 • 96 citations

Single molecule DNA sequencing in submicrometer channels: state of the art and future prospects

2001 • 87 citations

Progress towards single-molecule sequencing: enzymatic synthesis of nucleotide-specifically labeled DNA

2001 • 51 citations

Application of Single Molecule Detection to Dna Sequencing

1997 • 42 citations

Single-Molecule Fluorescence Observed with Mercury Lamp Illumination

1999 • 39 citations

Polyelectrolyte Surface Interface for Single-Molecule Fluorescence Studies of DNA Polymerase

2003 • 31 citations

Single-molecule DNA digestion by lambda-exonuclease

1999 • 31 citations

The Large Fragment of Escherichia coli DNA Polymerase I Can Synthesize DNA Exclusively from Fluorescently Labeled Nucleotides

2001 • 29 citations

Gene Researchers Hunt Bargains, Fixer-Uppers

2002 • 8 citations

Venter's Next Goal: 1000 Human Genomes

2002 • 8 citations

DNA-Sequencing at the single molecule level

2001 • 6 citations