A Genomic Regulatory Network for Development

Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty

1971 • 797 citations

Genomic Regulatory Systems: Development and Evolution

2005 • 710 citations

The hardwiring of development: organization and function of genomic regulatory systems

1997 • 704 citations

Nuclear β-catenin is required to specify vegetal cell fates in the sea urchin embryo

1999 • 440 citations

THE MECHANICS OF SEA URCHIN DEVELOPMENT, STUDIED BY OPERATIVE METHODS

1939 • 388 citations

Genomic Regulatory Systems

2001 • 327 citations

Specification of cell fate in the sea urchin embryo: summary and some proposed mechanisms

1998 • 268 citations

THE EARLY RADIATION AND PHYLOGENY OF ECHINODERMS

1984 • 251 citations

Introduction of cloned DNA into sea urchin egg cytoplasm: Replication and persistence during embryogenesis

1985 • 229 citations

Spatial mechanisms of gene regulation in metazoan embryos

1991 • 227 citations

LvNotch signaling mediates secondary mesenchyme specification in the sea urchin embryo

1999 • 209 citations

Cis-regulatory logic in the endo16 gene: switching from a specification to a differentiation mode of control

2001 • 206 citations

A Complete Second Gut Induced by Transplanted Micromeres in the Sea Urchin Embryo

1993 • 183 citations

Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila

1998 • 177 citations

Neuralized functions as an E3 ubiquitin ligase during Drosophila development

2001 • 152 citations

Micromeres are required for normal vegetal plate specification in sea urchin embryos

1995 • 144 citations

A fate map of the vegetal plate of the sea urchin (Lytechinus variegatus) mesenchyme blastula

1996 • 141 citations

Whole mount in situ hybridization shows Endo 16 to be a marker for the vegetal plate territory in sea urchin embryos

1993 • 131 citations

The Role of Brachyury (T) during Gastrulation Movements in the Sea Urchin Lytechinus variegatus

2001 • 127 citations

Identification and localization of a sea urchin Notch homologue: insights into vegetal plate regionalization and Notch receptor regulation

1997 • 127 citations

Animal–Vegetal Axis Patterning Mechanisms in the Early Sea Urchin Embryo

2000 • 122 citations

HpEts, an ets-related transcription factor implicated in primary mesenchyme cell differentiation in the sea urchin embryo

1999 • 112 citations

The role of micromere signaling in Notch activation and mesoderm specification during sea urchin embryogenesis

1999 • 109 citations

A large-scale analysis of mRNAs expressed by primary mesenchyme cells of the sea urchin embryo

2001 • 109 citations

SpKrl: a direct target of β-catenin regulation required for endoderm differentiation in sea urchin embryos

2001 • 100 citations

The allocation of early blastomeres to the ectoderm and endoderm is variable in the sea urchin embryo

1997 • 99 citations

Recovery of Developmentally Defined Gene Sets from High-Density cDNA Macroarrays

2000 • 92 citations

LvNotch signaling plays a dual role in regulating the position of the ectoderm-endoderm boundary in the sea urchin embryo

2001 • 88 citations

SpSoxB1, a maternally encoded transcription factor asymmetrically distributed among early sea urchin blastomeres

1999 • 87 citations

Spatial and temporal information processing in the sea urchin embryo: modular and intramodular organization of the CyIIIa gene cis-regulatory system

1996 • 85 citations

Neuralized functions cell autonomously to regulate Drosophila sense organ development

2000 • 84 citations

Ontogenic activation of a fusion gene introduced into sea urchin eggs.

1987 • 79 citations

Endo16, a lineage-specific protein of the sea urchin embryo, is first expressed just prior to gastrulation

1989 • 78 citations

Two Otx Proteins Generated from Multiple Transcripts of a Single Gene inStrongylocentrotus purpuratus

1997 • 74 citations

Late Specification of Veg1Lineages to Endodermal Fate in the Sea Urchin Embryo

1998 • 70 citations

Evolution of sea urchin retroviral-like (SURL) elements: evidence from 40 echinoid species

1999 • 57 citations

Requirement of SpOtx in Cell Fate Decisions in the Sea Urchin Embryo and Possible Role as a Mediator of β-Catenin Signaling

1999 • 50 citations

A Clonal Analysis of Secondary Mesenchyme Cell Fates in the Sea Urchin Embryo

1993 • 50 citations

A regulatory domain that directs lineage-specific expression of a skeletal matrix protein gene in the sea urchin embryo.

1988 • 50 citations

Transient appearance ofStrongylocentrotus purpuratus Otx in micromere nuclei: Cytoplasmic retention of SpOtx possibly mediated through an α-actinin interaction

1996 • 49 citations

Very early and transient vegetal-plate expression of SpKrox1, a Krüppel/Krox gene from Strongylocentrotus purpuratus

1996 • 44 citations

Endo16, a Large Multidomain Protein Found on the Surface and ECM of Endodermal Cells during Sea Urchin Gastrulation, Binds Calcium

1994 • 43 citations

Toward the Gene Catalogue of Sea Urchin Development: The Construction and Analysis of an Unfertilized Egg cDNA Library Highly Normalized by Oligonucleotide Fingerprinting

1999 • 37 citations

Spfkh1 encodes a transcription factor implicated in gut formation during sea urchin development

1997 • 23 citations

LiCl Perturbs Ectodermal Veg1Lineage Allocations inStrongylocentrotus purpuratusEmbryos

1997 • 14 citations