DC-SIGN promotes exogenous MHC-I–restricted HIV-1 antigen presentation

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

1995 • 2,531 citations

DC-SIGN, a Dendritic Cell–Specific HIV-1-Binding Protein that Enhances trans-Infection of T Cells

2000 • 2,384 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

Efficient Targeting of Protein Antigen to the Dendritic Cell Receptor DEC-205 in the Steady State Leads to Antigen Presentation on Major Histocompatibility Complex Class I Products and Peripheral CD8+ T Cell Tolerance

2002 • 1,296 citations

Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

1998 • 990 citations

The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

1995 • 959 citations

Epoxomicin, a potent and selective proteasome inhibitor, exhibitsin vivoantiinflammatory activity

1999 • 914 citations

DC-SIGN (CD209) Mediates Dengue Virus Infection of Human Dendritic Cells

2003 • 854 citations

C-type lectin receptors on dendritic cells and langerhans cells

2002 • 824 citations

BDCA-2, a Novel Plasmacytoid Dendritic Cell–specific Type II C-type Lectin, Mediates Antigen Capture and Is a Potent Inhibitor of Interferon α/β Induction

2001 • 749 citations

Recruitment of HIV and Its Receptors to Dendritic Cell-T Cell Junctions

2003 • 692 citations

Structural Basis for Selective Recognition of Oligosaccharides by DC-SIGN and DC-SIGNR

2001 • 659 citations

DC-SIGN Is the Major Mycobacterium tuberculosis Receptor on Human Dendritic Cells

2002 • 620 citations

Antigen processing by the proteasome

2001 • 620 citations

The Dendritic Cell-Specific Adhesion Receptor DC-SIGN Internalizes Antigen for Presentation to T Cells

2002 • 613 citations

Diversity of receptors binding HIV on dendritic cell subsets

2002 • 515 citations

DC-SIGN-Mediated Internalization of HIV Is Required for Trans-Enhancement of T Cell Infection

2002 • 513 citations

Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1

1994 • 505 citations

Dendritic‐cell‐specific ICAM3‐grabbing non‐integrin is essential for the productive infection of human dendritic cells by mosquito‐cell‐derived dengue viruses

2003 • 495 citations

Hepatitis C Virus Glycoproteins Interact with DC-SIGN and DC-SIGNR

2003 • 382 citations

Epitopes of the CD4 Antigen and HIV Infection

1986 • 379 citations

The C‐type lectin DC‐SIGN (CD209) is an antigen‐uptake receptor for Candida albicans on dendritic cells

2003 • 365 citations

DC-SIGN and L-SIGN Are High Affinity Binding Receptors for Hepatitis C Virus Glycoprotein E2

2003 • 363 citations

Human Cytomegalovirus Binding to DC-SIGN Is Required for Dendritic Cell Infection and Target Cell trans-Infection

2002 • 358 citations

Immature Dendritic Cells Selectively Replicate Macrophagetropic (M-Tropic) Human Immunodeficiency Virus Type 1, while Mature Cells Efficiently Transmit both M- and T-Tropic Virus to T Cells

1998 • 325 citations

Mannose receptor‐mediated uptake of antigens strongly enhances HLA class II‐restricted antigen presentation by cultured dendritic cells

1997 • 324 citations

Human Immunodeficiency Virus Type 1 Entry into Macrophages Mediated by Macropinocytosis

2001 • 278 citations

Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell

1995 • 266 citations

Expression of DC-SIGN by Dendritic Cells of Intestinal and Genital Mucosae in Humans and Rhesus Macaques

2002 • 256 citations

Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation

1992 • 250 citations

Therapeutic dendritic-cell vaccine for simian AIDS

2002 • 239 citations

Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1.

1994 • 221 citations

Cytosolic Gag p24 as an Index of Productive Entry of Human Immunodeficiency Virus Type 1

1998 • 206 citations

HIV-1 Nef-Induced Upregulation of DC-SIGN in Dendritic Cells Promotes Lymphocyte Clustering and Viral Spread

2002 • 189 citations

cisExpression of DC-SIGN Allows for More Efficient Entry of Human and Simian Immunodeficiency Viruses via CD4 and a Coreceptor

2001 • 179 citations

MHC-I–restricted presentation of HIV-1 virion antigens without viral replication

2001 • 153 citations

Virus replication begins in dendritic cells during the transmission of HIV-1 from mature dendritic cells to T cells

1999 • 122 citations

Activation of HIV-1 specific CD4 and CD8 T cells by human dendritic cells: roles for cross-presentation and non-infectious HIV-1 virus

2002 • 118 citations

Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: a candidate SIV vaccine.

1998 • 115 citations

Alternative pathways for processing exogenous and endogenous antigens that can generate peptides for MHC class I‐restricted presentation

1999 • 106 citations

Broadly cross-reactive HIV-specific cytotoxic T-lymphocytes in highly-exposed persistently seronegative donors

1999 • 105 citations

Serotyping of HIV Type 1 Infections: Definition, Relationship to Viral Genetic Subtypes, and Assay Evaluation

1998 • 102 citations

Quantitative Expression and Virus Transmission Analysis of DC-SIGN on Monocyte-Derived Dendritic Cells

2002 • 101 citations

A fatal attraction: Mycobacterium tuberculosis and HIV-1 target DC-SIGN to escape immune surveillance

2003 • 100 citations

Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN

2002 • 99 citations

Cell type-dependent retention and transmission of HIV-1 by DC-SIGN

2003 • 86 citations

Nef Is Required for Efficient HIV-1 Replication in Cocultures of Dendritic Cells and Lymphocytes

2001 • 69 citations

Induction of Anti-Human Immunodeficiency Virus Type 1 (HIV-1) CD8⁺and CD4⁺T-Cell Reactivity by Dendritic Cells Loaded with HIV-1 X4-Infected Apoptotic Cells

2002 • 53 citations

Inhibition of Human Immunodeficiency Virus Type 1 Env-Mediated Fusion by DC-SIGN

2003 • 41 citations

Monocyte-derived dendritic cells: development of a cellular processor for clinical applications

1998 • 33 citations

Dendritic Cells as A Conduit to Improve HIV Vaccines

2003 • 21 citations

Deleted Work

1955 • 0 citations

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