Virus replication begins in dendritic cells during the transmission of HIV-1 from mature dendritic cells to T cells

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

Genotypic and Phenotypic Characterization of HIV-1 Patients with Primary Infection

1993 • 1,258 citations

Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability

1996 • 1,138 citations

TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor

1997 • 869 citations

Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.

1995 • 756 citations

Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques.

1996 • 705 citations

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood

1996 • 696 citations

Migration and maturation of Langerhans cells in skin transplants and explants.

1990 • 663 citations

Dendritic Cells Exposed to Human Immunodeficiency Virus Type-1 Transmit a Vigorous Cytopathic Infection to CD4 ⁺ T Cells

1992 • 624 citations

In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells

1997 • 560 citations

Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1

1994 • 505 citations

Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission.

1994 • 496 citations

Identification of proliferating dendritic cell precursors in mouse blood.

1992 • 445 citations

CD40 Ligand-Dependent T Cell Activation: Requirement of B7-CD28 Signaling Through CD40

1996 • 421 citations

A Novel Lysosome-Associated Membrane Glycoprotein, DC-LAMP, Induced upon DC Maturation, Is Transiently Expressed in MHC Class II Compartment

1998 • 402 citations

Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: Implications for HIV primary infection

1997 • 398 citations

Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles

1996 • 384 citations

Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.

1994 • 379 citations

Pathway of vesicular stomatitis virus entry leading to infection

1982 • 375 citations

Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A

1997 • 353 citations

CD40-CD40 Ligand: A Multifunctional Receptor-Ligand Pair

1996 • 326 citations

Immature Dendritic Cells Selectively Replicate Macrophagetropic (M-Tropic) Human Immunodeficiency Virus Type 1, while Mature Cells Efficiently Transmit both M- and T-Tropic Virus to T Cells

1998 • 325 citations

Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells.

1994 • 276 citations

A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph.

1996 • 261 citations

Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors

1996 • 245 citations

Migration patterns of dendritic cells in the mouse. Homing to T cell-dependent areas of spleen, and binding within marginal zone.

1988 • 226 citations

Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells.

1995 • 223 citations

Indicator Cell Lines for Detection of Primary Strains of Human and Simian Immunodeficiency Viruses

1997 • 206 citations

HIV-1 Directly Kills CD4+ T Cells by a Fas-independent Mechanism

1998 • 199 citations

Recent advances in the study of dendritic cells and follicular dendritic cells

1995 • 191 citations

Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways.

1997 • 191 citations

Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1.

1995 • 174 citations

HIV-1 Selection by Epidermal Dendritic Cells during Transmission across Human Skin

1998 • 159 citations

The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection

1994 • 128 citations

Both a precursor and a mature population of dendritic cells can bind HIV. However, only the mature population that expresses CD80 can pass infection to unstimulated CD4+ T cells.

1995 • 117 citations

Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia.

1995 • 115 citations

Entry Into Afferent Lymphatics and Maturation In Situ of Migrating Murine Cutaneous Dendritic Cells

1998 • 113 citations

Infection and Apoptotic Cell Death of CD4⁺T Cells during an Immune Response to HIV-1-Pulsed Dendritic Cells

1994 • 95 citations

Mature Dendritic Cells Respond to SDF-1, but not to Several β-Chemokines

1998 • 94 citations

Monocyte-derived cultured dendritic cells are susceptible to human immunodeficiency virus infection and transmit virus to resting T cells in the process of nominal antigen presentation

1995 • 93 citations

Localization of SIV in the genital tract of chronically infected female rhesus macaques.

1992 • 89 citations

Efficient Virus Transmission from Dendritic Cells to CD4+T Cells in Response to Antigen Depends on Close Contact through Adhesion Molecules

1997 • 70 citations

Quantitation by competitive PCR of HIV-1 proviral DNA in epidermal Langerhans cells of HIV-infected patients.

1994 • 63 citations

Expression of Maturation-/Migration-Related Molecules on Human Dendritic Cells from Blood and Skin

1998 • 60 citations

The effect of in vitro human immunodeficiency virus infection on dendritic-cell differentiation and function

1996 • 54 citations

Dendritic Cells Transmit Human Immunodeficiency Virus Type 1 to Monocytes and Monocyte-Derived Macrophages

1998 • 40 citations

Cellular targets of infection and route of viral dissemination following an intravaginal inoculation of SIV into rhesus macaques

1998 • 20 citations

The HIV-1 Life Cycle is Blocked at Two Different Points in Mature Dendritic Cells

1997 • 14 citations

Cited By (0)

No citing papers found in database