C-type lectin receptors on dendritic cells and langerhans cells

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

1995 • 2,531 citations

DC-SIGN, a Dendritic Cell–Specific HIV-1-Binding Protein that Enhances trans-Infection of T Cells

2000 • 2,384 citations

Identification of DC-SIGN, a Novel Dendritic Cell–Specific ICAM-3 Receptor that Supports Primary Immune Responses

2000 • 1,665 citations

A new receptor for β-glucans

2001 • 1,498 citations

BDCA-2, BDCA-3, and BDCA-4: Three Markers for Distinct Subsets of Dendritic Cells in Human Peripheral Blood

2000 • 1,282 citations

Identification of a Ten-Amino Acid Proline-Rich SH3 Binding Site

1993 • 1,205 citations

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

1974 • 1,041 citations

The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

1995 • 959 citations

Langerin, a Novel C-Type Lectin Specific to Langerhans Cells, Is an Endocytic Receptor that Induces the Formation of Birbeck Granules

2000 • 934 citations

BDCA-2, a Novel Plasmacytoid Dendritic Cell–specific Type II C-type Lectin, Mediates Antigen Capture and Is a Potent Inhibitor of Interferon α/β Induction

2001 • 749 citations

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

1974 • 694 citations

The Toll receptor family and microbial recognition

2000 • 671 citations

Structural Basis for Selective Recognition of Oligosaccharides by DC-SIGN and DC-SIGNR

2001 • 659 citations

The mannose receptor is a pattern recognition receptor involved in host defense

1998 • 640 citations

The Dendritic Cell-Specific Adhesion Receptor DC-SIGN Internalizes Antigen for Presentation to T Cells

2002 • 613 citations

Local control of the immune response in the liver

2000 • 593 citations

Receptor-mediated pinocytosis of mannose glycoconjugates by macrophages: Characterization and evidence for receptor recycling

1980 • 574 citations

The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments

2000 • 546 citations

DC-SIGN–ICAM-2 interaction mediates dendritic cell trafficking

2000 • 498 citations

A Novel Mechanism of Carbohydrate Recognition by the C-type Lectins DC-SIGN and DC-SIGNR

2001 • 497 citations

Identification of a Novel, Dendritic Cell-associated Molecule, Dectin-1, by Subtractive cDNA Cloning

2000 • 457 citations

Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes.

1992 • 437 citations

Molecular Bases for the Recognition of Tyrosine-based Sorting Signals

1999 • 414 citations

A Novel Lysosome-Associated Membrane Glycoprotein, DC-LAMP, Induced upon DC Maturation, Is Transiently Expressed in MHC Class II Compartment

1998 • 402 citations

The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells

1997 • 397 citations

Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients

2001 • 394 citations

Sequence and expression of a membrane-associated C-type lectin that exhibits CD4-independent binding of human immunodeficiency virus envelope glycoprotein gp120.

1992 • 381 citations

Primary structure of the mannose receptor contains multiple motifs resembling carbohydrate-recognition domains.

1990 • 370 citations

A Dendritic Cell–Specific Intercellular Adhesion Molecule 3–Grabbing Nonintegrin (Dc-Sign)–Related Protein Is Highly Expressed on Human Liver Sinusoidal Endothelial Cells and Promotes HIV-1 Infection

2001 • 351 citations

DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans

2001 • 322 citations

The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface

1999 • 282 citations

Cutting Edge: DC-SIGN; a Related Gene, DC-SIGNR; and CD23 Form a Cluster on 19p13

2000 • 257 citations

APCs Express DCIR, a Novel C-Type Lectin Surface Receptor Containing an Immunoreceptor Tyrosine-Based Inhibitory Motif

1999 • 255 citations

Isolation and Characterization of a Mannan-Binding Protein from Human Serum1

1983 • 235 citations

Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells

2000 • 214 citations

A Novel Phosphotyrosine Motif with a Critical Amino Acid at Position −2 for the SH2 Domain-mediated Activation of the Tyrosine Phosphatase SHP-1

1997 • 199 citations

Cloning of a Second Dendritic Cell-associated C-type Lectin (Dectin-2) and Its Alternatively Spliced Isoforms

2000 • 165 citations

The Cysteine-Rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates a and B and Sulfated Oligosaccharides of Blood Group Lewisa and Lewisx Types in Addition to the Sulfated N-Glycans of Lutropin

2000 • 164 citations

Carbohydrate-mediated recognition systems in innate immunity

2000 • 161 citations

Expression of multilectin receptors and comparative FITC–dextran uptake by human dendritic cells

2000 • 158 citations

Divergent functions of lectin‐like receptors on NK cells

1997 • 135 citations

C-Type lectin-like domains in Caenorhabditis elegans: predictions from the complete genome sequence

1999 • 133 citations

The role of dendritic cells in the innate immune system

2000 • 117 citations

C-Type Lectins and Sialyl Lewis X Oligosaccharides

1999 • 116 citations

Immature Human Dendritic Cells Express Asialoglycoprotein Receptor Isoforms for Efficient Receptor-Mediated Endocytosis

2001 • 116 citations

Extensive Repertoire of Membrane-bound and Soluble Dendritic Cell-specific ICAM-3-grabbing Nonintegrin 1 (DC-SIGN1) and DC-SIGN2 Isoforms

2001 • 106 citations

Identification of a human homologue of the dendritic cell-associated C-type lectin-1, dectin-1

2001 • 102 citations

Secretion of TNF-α by alveolar macrophages in response to Candida albicans mannan

1994 • 101 citations

cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells

1998 • 66 citations

Dermal Microvascular Endothelial Cells Express the 180-kDa Macrophage Mannose Receptor In Situ and In Vitro

2000 • 62 citations

Structure of the gene coding for the human early lymphocyte activation antigen CD69: A C‐type lectin receptor evolutionarily related with the gene families of natural killer cell‐specific receptors

1994 • 60 citations

Human dendritic cells shed a functional, soluble form of the mannose receptor

1999 • 59 citations

New structural insights into lectin-type proteins of the immune system

2001 • 55 citations

CD69, An Early Activation Antigen on Lymphocytes, Is Constitutively Expressed by Human Epidermal Langerhans Cells

1992 • 47 citations

The interaction of a lung surfactant protein (SP-A) with macrophages is mannose dependent.

1989 • 42 citations

Cloning and Characterization of a Novel ITIM Containing Lectin-like Immunoreceptor LLIR and Its Two Transmembrane Region Deletion Variants

2001 • 36 citations

Differentially induced expression of C-type lectins in activated lymphocytes

2001 • 24 citations

The ins and outs of getting in: structures and signals that enhance BCR or Fc receptor-mediated antigen presentation

2000 • 12 citations

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