Back to search

Involvement of the vascular endothelial growth factor receptor-1 in murine hepatocellular carcinoma development

Data up to Jan 2025

Published2004
Citations27
References41

Total Citations Per Year

Abstract

References (41)

The biology of VEGF and its receptors

2003 • 9,272 citations

Angiogenesis in cancer and other diseases

2000 • 8,734 citations

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

Angiogenesis in health and disease

2003 • 4,127 citations

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

2001 • 1,874 citations

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

1994 • 1,661 citations

Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.

2000 • 1,536 citations

Angiostatin induces and sustains dormancy of human primary tumors in mice

1996 • 1,193 citations

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

1998 • 1,077 citations

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

2002 • 1,066 citations

Tumor angiogenesis: past, present and the near future

2000 • 973 citations

Clinical Application of Antiangiogenic Therapy: Microvessel Density, What It Does and Doesn't Tell Us

2002 • 794 citations

Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors.

1999 • 660 citations

Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment

2002 • 638 citations

Hepatocellular carcinoma: Diagnosis and treatment

2002 • 590 citations

Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

1997 • 512 citations

Structure and Function of VEGF/VEGF-receptor System Involved in Angiogenesis.

2001 • 508 citations

Hepatocellular carcinoma

1999 • 453 citations

The Vascular Endothelial Growth Factor Receptor KDR Activates Multiple Signal Transduction Pathways in Porcine Aortic Endothelial Cells

1997 • 436 citations

Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis

2000 • 423 citations

Expression of vascular endothelial growth factor in human hepatocellular carcinoma

1998 • 387 citations

Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis.

2001 • 345 citations

Clinical significance of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor

1996 • 306 citations

The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-γ pathway and partially induces mitotic signals in NIH3T3 fibroblasts

1997 • 305 citations

Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells

2000 • 291 citations

Signaling via Vascular Endothelial Growth Factor Receptors

1999 • 281 citations

Structure and dual function of vascular endothelial growth factor receptor-1 (Flt-1)

2001 • 252 citations

Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma.

1996 • 221 citations

The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor.

2001 • 208 citations

Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells.

1997 • 203 citations

Vascular endothelial growth factor as a marker of tumor endothelium.

1998 • 168 citations

The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells

2001 • 155 citations

Synergistic effect of basic fibroblast growth factor and vascular endothelial growth factor in murine hepatocellular carcinoma

2002 • 149 citations

Importance of orthotopic implantation for human tumors as model systems: relevance to metastasis and invasion

1993 • 127 citations

Mammary carcinoma cells over-expressing tissue inhibitor of metalloproteinases-1show vascular endothelial growth factor expression

1998 • 119 citations

Vascular Endothelial Growth Factor Tightly Regulates In Vivo Development of Murine Hepatocellular Carcinoma Cells

1998 • 102 citations

Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues.

2000 • 97 citations

KDR/Flk-1 is a major regulator of vascular endothelial growth factor-induced tumor development and angiogenesis in murine hepatocellular carcinoma cells

1999 • 93 citations

Suppression of the renin-angiotensin system attenuates vascular endothelial growth factor-mediated tumor development and angiogenesis in murine hepatocellular carcinoma cells

2002 • 60 citations

The vascular endothelial growth factor receptor KDR/Flk-1 is a major regulator of malignant ascites formation in the mouse hepatocellular carcinoma model

2001 • 56 citations

Hepatocellular carcinoma in an orthotopic mouse model metastasizes intrahepatically in cirrhotic but not in normal liver

1999 • 33 citations

Cited By (0)

No citing papers found in database

Involvement of the vascular endothelial growth factor receptor-1 in murine hepatocellular… (2004) – Journal of Hepatology | Metascience Observatory Explorer