Involvement of the vascular endothelial growth factor receptor-1 in murine hepatocellular carcinoma development
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References (41)
The biology of VEGF and its receptors
2003 • 9,272 citations
Angiogenesis in cancer and other diseases
2000 • 8,734 citations
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
1992 • 4,885 citations
Angiogenesis in health and disease
2003 • 4,127 citations
Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
2001 • 1,874 citations
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.
1994 • 1,661 citations
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.
2000 • 1,536 citations
Angiostatin induces and sustains dormancy of human primary tumors in mice
1996 • 1,193 citations
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
1998 • 1,077 citations
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
2002 • 1,066 citations
Tumor angiogenesis: past, present and the near future
2000 • 973 citations
Clinical Application of Antiangiogenic Therapy: Microvessel Density, What It Does and Doesn't Tell Us
2002 • 794 citations
Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors.
1999 • 660 citations
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment
2002 • 638 citations
Hepatocellular carcinoma: Diagnosis and treatment
2002 • 590 citations
Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
1997 • 512 citations
Structure and Function of VEGF/VEGF-receptor System Involved in Angiogenesis.
2001 • 508 citations
Hepatocellular carcinoma
1999 • 453 citations
The Vascular Endothelial Growth Factor Receptor KDR Activates Multiple Signal Transduction Pathways in Porcine Aortic Endothelial Cells
1997 • 436 citations
Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis
2000 • 423 citations
Expression of vascular endothelial growth factor in human hepatocellular carcinoma
1998 • 387 citations
Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis.
2001 • 345 citations
Clinical significance of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor
1996 • 306 citations
The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-γ pathway and partially induces mitotic signals in NIH3T3 fibroblasts
1997 • 305 citations
Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells
2000 • 291 citations
Signaling via Vascular Endothelial Growth Factor Receptors
1999 • 281 citations
Structure and dual function of vascular endothelial growth factor receptor-1 (Flt-1)
2001 • 252 citations
Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma.
1996 • 221 citations
The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor.
2001 • 208 citations
Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells.
1997 • 203 citations
Vascular endothelial growth factor as a marker of tumor endothelium.
1998 • 168 citations
The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells
2001 • 155 citations
Synergistic effect of basic fibroblast growth factor and vascular endothelial growth factor in murine hepatocellular carcinoma
2002 • 149 citations
Importance of orthotopic implantation for human tumors as model systems: relevance to metastasis and invasion
1993 • 127 citations
Mammary carcinoma cells over-expressing tissue inhibitor of metalloproteinases-1show vascular endothelial growth factor expression
1998 • 119 citations
Vascular Endothelial Growth Factor Tightly Regulates In Vivo Development of Murine Hepatocellular Carcinoma Cells
1998 • 102 citations
Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues.
2000 • 97 citations
KDR/Flk-1 is a major regulator of vascular endothelial growth factor-induced tumor development and angiogenesis in murine hepatocellular carcinoma cells
1999 • 93 citations
Suppression of the renin-angiotensin system attenuates vascular endothelial growth factor-mediated tumor development and angiogenesis in murine hepatocellular carcinoma cells
2002 • 60 citations
The vascular endothelial growth factor receptor KDR/Flk-1 is a major regulator of malignant ascites formation in the mouse hepatocellular carcinoma model
2001 • 56 citations
Hepatocellular carcinoma in an orthotopic mouse model metastasizes intrahepatically in cirrhotic but not in normal liver
1999 • 33 citations
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