Parallel modulation of catecholamine activation of adenylate cyclase and formation of the high-affinity agonist.cntdot.receptor complex in turkey erythrocyte membranes by temperature and cis-vaccenic acid

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

1980 • 1,579 citations

Lateral diffusion of rhodopsin in the photoreceptor membrane

1974 • 658 citations

Mathematical theory of complex ligand-binding systems at equilibrium: Some methods for parameter fitting

1972 • 615 citations

A quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data.

1980 • 545 citations

Relationship between the beta-adrenergic receptor and adenylate cyclase.

1977 • 497 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 487 citations

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

1978 • 480 citations

GTP-binding proteins in membranes and the control of adenylate cyclase activity.

1977 • 456 citations

Rotational and Translational Diffusion in Membranes

1974 • 443 citations

Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.

1978 • 372 citations

Mode of coupling between the β-adrenergic receptor and adenylate cyclase in turkey erythrocytes

1978 • 347 citations

Fundamental difference between the molecular interactions of agonists and antagonists with the β-adrenergic receptor

1979 • 259 citations

Identification of adenylate cyclase-coupled beta-adrenergic receptors in frog erythrocytes with (minus)-[3-H] alprenolol.

1975 • 248 citations

Agonist-promoted coupling of the beta-adrenergic receptor with the guanine nucleotide regulatory protein of the adenylate cyclase system.

1980 • 229 citations

Slowly reversible binding of catecholamine to a nucleotide-sensitive state of the beta-adrenergic receptor.

1977 • 228 citations

Hydrodynamic properties of the beta-adrenergic receptor and adenylate cyclase from wild type and varient S49 lymphoma cells.

1977 • 216 citations

Mode of coupling between hormone receptors and adenylate cyclase elucidated by modulation of membrane fluidity

1978 • 202 citations

Adenylate cyclase activation by the .beta.-adrenergic receptors as a diffusion-controlled process

1979 • 199 citations

Fatty acids as modulators of membrane functions: catecholamine-activated adenylate cyclase of the turkey erythrocyte.

1975 • 187 citations

The Role of Acidic Phospholipids in Glucagon Action on Rat Liver Adenylate Cyclase

1973 • 182 citations

Resolution of beta-adrenergic receptor binding and adenylate cyclase activity by gel exclusion chromatography.

1977 • 156 citations

Agonist-specific effects of guanine nucleotides on alpha-adrenergic receptors in human platelets.

1979 • 155 citations

A high affinity agonist . beta-adrenergic receptor complex is an intermediate for catecholamine stimulation of adenylate cyclase in turkey and frog erythrocyte membranes.

1980 • 152 citations

Structure and processing of yeast precursor tRNAs containing intervening sequences

1978 • 149 citations

Guanine nucleotide‐controlled interactions between components of adenylate cyclase

1979 • 144 citations

Antibodies against chromosomal HMG proteins stain the cytoplasm of mammalian cells

1979 • 139 citations

Agonist-induced increase in apparent β-adrenergic receptor size

1978 • 138 citations

Cyclic AMP metabolism in cholesterol-rich platelets.

1977 • 128 citations

Uncoupling of Catecholamine Activation of Pigeon Erythrocyte Membrane Adenylate Cyclase by Filipin

1974 • 124 citations

Beta-Adrenergic receptor interactions. Direct comparison of receptor interaction and biological activity.

1976 • 124 citations

Modulation of the .beta.-receptor adenylate cyclase interactions in cultured Chang liver cells by phospholipid enrichment

1979 • 101 citations

Effect of liposomes containing cholesterol on adenylate cyclase activity of cultured mammalian fibroblasts

1978 • 83 citations

Multiple effects of guanosine triphosphate on beta adrenergic receptors and adenylate cyclase activity in rat heart, lung and brain.

1979 • 64 citations

Temperature-dependent changes in binding to beta-adrenergic receptors of intact S49 lymphoma cells. Implications for the state of the receptor that activates adenylate cyclase under physiological conditions.

1979 • 54 citations

Agonist-specific alterations in receptor binding affinity associated with solubilization of turkey erythrocyte membrane beta adrenergic receptors.

1978 • 46 citations