Lesion selectivity in blockage of lambda exonuclease by DNA damage

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1982 • 1,398 citations

The molecular origin of DNA-drug specificity in netropsin and distamycin.

1985 • 800 citations

Reevaluation of interaction of cis-dichloro(ethylenediamine)platinum(II) with DNA

1986 • 450 citations

DNA structural variations in the E. coli tyrT promoter

1984 • 448 citations

An Exonuclease Induced by Bacteriophage λ

1967 • 346 citations

Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II)

1983 • 329 citations

Structure of DNase I at 2.0 Å resolution suggests a mechanism for binding to and cutting DNA

1986 • 327 citations

Structures of benzo(a)pyrene–nucleic acid adducts formed in human and bovine bronchial explants

1977 • 299 citations

Binding of cis - and trans -Dichlorodiammineplatinum(II) to DNA: Evidence for Unwinding and Shortening of the Double Helix

1979 • 254 citations

Thymine dimers bend DNA.

1988 • 172 citations

The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove.

1988 • 166 citations

DNA binding and mutation spectra of the carcinogen N-2-aminofluorene in Escherichia coli

1985 • 146 citations

Use of exonuclease III to determine the site of stable lesions in defined sequences of DNA: the cyclobutane pyrimidine dimer and cis and trans dichlorodiammine platinum II examples

1981 • 144 citations

Proposed structure of the anthramycin–DNA adduct

1979 • 121 citations

Sequence context effects on 8-methoxypsoralen photobinding to defined DNA fragments

1987 • 117 citations

Regulation of λ exonuclease

1966 • 111 citations

Bovine pancreatic deoxyribonuclease A. Isolation of cyanogen bromide peptides; complete covalent structure of the polypeptide chain.

1992 • 107 citations

T4 DNA polymerase (3′–5′) exonuclease, an enzyme for the detection and quantitation of stable DNA lesions: the ultraviolet light example

1985 • 104 citations

Carcinogen-induced alteration of DNA structure.

1981 • 104 citations

Determination of pyrimidine dimer unwinding angle by measurement of DNA electrophoretic mobility

1982 • 96 citations

DNA binding spectrum of the carcinogen N-acetoxy-N-2-acetylaminofluorene significantly differs from the mutation spectrum

1984 • 96 citations

Sequence specificity in photoreaction of various psoralen derivatives with DNA: role in biological activity

1988 • 86 citations

Minor products from the reaction of (+) and (−) benzo[a]-pyrene-anti-diolepoxide with DNA

1981 • 80 citations

Spectrum of cisplatin-induced mutations in Escherichia coli.

1987 • 76 citations

Gene size differentially affects the binding of yeast transcription factor tau to two intragenic regions.

1987 • 75 citations

Mechanism of DNA strand breakage by piperidine at sites of N7-alkylguanines

1986 • 72 citations

GC-rich regions in genomes as targets for DNA alkylation

1988 • 66 citations

The N2-guanine adduct but not the C8-guanine of N6-adenine adducts formed by 4-nitroquinoline 1-oxide blocks the 3'-5' exonuclease action of T4 DNA polymerase

1990 • 53 citations

Characterization of the ternary complexes formed in the reaction of cis-diamminedichloro platinum (II), ethidium bromide and nucleic acids

1987 • 50 citations

Structure of the anthramycin-d(ATGCAT)2 adduct from one- and two-dimensional proton NMR experiments in solution

1985 • 36 citations

The reaction of anthramycin with DNA

1974 • 30 citations

Cross-linking and relaxation of supercoiled DNA by psoralen and light

1978 • 24 citations

Detection of neocarzinostatin chromophore-deoxyribose adducts as exonuclease-resistant sites in defined-sequence DNA

1985 • 24 citations

High resolution psoralen mapping reveals an altered DNA helical structure in the SV40 regulatory region

1988 • 18 citations

Secondary structure of phage T2 DNA.

1972 • 7 citations