The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove.

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

DNA bending at adenine · thymine tracts

1986 • 1,032 citations

Cisplatin

1984 • 942 citations

Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA

1985 • 436 citations

Energetics of DNA twisting

1983 • 410 citations

The Mechanism of Action of Antitumor Platinum Compounds

1979 • 408 citations

X-Ray Structure of the Major Adduct of the Anticancer Drug Cisplatin with DNA: cis -[Pt(NH ₃ ) ₂ {d(pGpG)}]

1985 • 403 citations

Curved DNA: design, synthesis, and circularization.

1986 • 303 citations

Binding of cis - and trans -Dichlorodiammineplatinum(II) to DNA: Evidence for Unwinding and Shortening of the Double Helix

1979 • 254 citations

DNA bend direction by phase sensitive detection

1987 • 252 citations

Calibration of DNA curvature and a unified description of sequence-directed bending.

1988 • 251 citations

Conformational analysis of the adductcis[Pt(NH₃)₂{d(GpG)}]⁺in aqueous solution. A high field (500–300 MHz) nuclear magnetic resonance investigation

1982 • 125 citations

Bending and flexibility of kinetoplast DNA

1986 • 125 citations

Cis-diamminedichloroplatinum(II) Induced Distortion of a Single and Double Stranded Deoxydecanucleosidenona-phosphate Studied by Nuclear Magnetic Resonance

1985 • 75 citations

Molecular mechanics modeling of oligonucleotide adducts of the antitumor drug cis‐diamminedichloroplatinum(II)

1987 • 61 citations

Unwinding of supercoiled DNA by cis- and trans-diamminedichloroplatinum(II): influence of the torsional strain on DNA unwinding

1985 • 46 citations

Cis- and trans-diamminedichloroplatinum(II) binding produces different tertiary structural changes on SV40 DNA

1982 • 35 citations