Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II)

DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity.

1979 • 402 citations

Isolation of the hydrocarbon-deoxyribonucleoside products from the DNA of mouse embryo cells treated in culture with 7-methylbenz(a)anthracene-3H.

1973 • 181 citations

Detection and quantification of adducts formed upon interaction of diamminedichloroplatinum (II) with DNA, by anion-exchange chromatography after enzymatic degradation

1982 • 150 citations

Use of exonuclease III to determine the site of stable lesions in defined sequences of DNA: the cyclobutane pyrimidine dimer and cis and trans dichlorodiammine platinum II examples

1981 • 144 citations

Inhibition of the BamHI cleavage and unwinding of pBR322 deoxyribonucleic acid by the antitumor drug cis-dichlorodiammineplatinum(II)

1981 • 138 citations

Thiourea Reverses Cross-Links and Restores Biological Activity in DNA Treated with Dichlorodiaminoplatinum(II)

1979 • 96 citations

cis-Diamminedichloroplatinum(II) binds in a unique manner to oligo(dG).oligo(dC) sequences in DNA - a new assay using exonuclease III

1981 • 90 citations

Separation and characterization of products resulting from the reaction of cis-diamminedichloroplatinum(II) with deoxyribonucleosides

1982 • 77 citations

The reaction of 14C-labelled platinum ethylenediamine dichloride with nucleic acid constituents

1973 • 73 citations

Quantitative aspects of the formation and loss of DNA interstrand crosslinks in Chinese hamster cells following treatment with cis-diamminedichloroplatinum(II) (cisplatin) II. Comparison of results from alkaline elution, DNA renaturation and DNA sedimentation studies

1981 • 70 citations

The significance of DNA cross-linking to cis-diamminedichloroplatinum(II)-induced cytotoxicity in sensitive and resistant lines of murine leukemia L1210 cells

1982 • 69 citations

Effect of thiourea on survival and DNA cross-link formation in cells treated with platinum(II) complexes, L-phenylalanine mustard, and bis(2-chloroethyl)methylamine.

1979 • 66 citations

Intrastrand crosslinking of the guanines of the deoxytrinucleotide d(G-C-G) via cis-diammineplatinum dichloride

1982 • 59 citations

Quantitative aspects of the formation and loss of DNA interstrand crosslinks in Chinese hamster cells following treatment with cis-diamminedichloroplatinum(II) (cisplatin) I. Proportion of DNA-platinum reactions involved in DNA crosslinking

1981 • 58 citations

Renaturation effects of cis and trans platinum II and IV compounds on calf thymus deoxyribonucleic acid

1975 • 55 citations

Platinum-DNA crosslinking: platinum antitumor drug interactions with native lambda bacteriophage DNA studied using a restriction endonuclease

1978 • 54 citations

Studies on the resistance of a murine leukemia L1210 cell line to cis-diamminedichloroplatinium(II)

1981 • 44 citations

The nature of inactivating lesions produced by platinum (II) complexes in phage λ DNA

1980 • 42 citations

Comparison of the interaction of cis- and trans-diamminedichloroplatinum(II) with DNA by a simple filter binding assay

1982 • 29 citations

Preferential Interstrand Cross-Linking of DNA Rich in Guanine and Cytosine by cis-Dichlorodiammineplatinum(II)

1979 • 27 citations

Formation and removal of benzo(a)pyrene adducts of DNA in hamster tracheal epithelial cells.

1981 • 26 citations