β-Catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

1997 • 3,847 citations

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

1999 • 3,566 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

1997 • 3,234 citations

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

Identification and characterization of the familial adenomatous polyposis coli gene

1991 • 2,806 citations

Identification of FAP Locus Genes from Chromosome 5q21

1991 • 2,358 citations

APC mutations occur early during colorectal tumorigenesis

1992 • 1,901 citations

XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos

1996 • 1,827 citations

The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.

1989 • 1,393 citations

Association of the APC Gene Product with β-Catenin

1993 • 1,215 citations

Association of the APC Tumor Suppressor Protein with Catenins

1993 • 1,202 citations

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.

1995 • 1,025 citations

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

1998 • 998 citations

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

1994 • 969 citations

Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.

1992 • 562 citations

An HMG-box-containing T-cell factor required for thymocyte differentiation

1995 • 518 citations

The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

1996 • 494 citations

Signal transduction by β-catenin

1995 • 398 citations

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia.

1995 • 304 citations

A truncated beta-catenin disrupts the interaction between E-cadherin and alpha-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines.

1994 • 284 citations

Association between a transmembrane protein tyrosine phosphatase and the cadherin-catenin complex.

1996 • 251 citations

Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis

1993 • 249 citations

Loss of E-Cadherin-Dependent Cell-Cell Adhesion due to Mutation of the β-Catenin Gene in a Human Cancer Cell Line, HSC-39

1995 • 225 citations

Regulated binding of PTP1B-like phosphatase to N-cadherin: control of cadherin-mediated adhesion by dephosphorylation of beta-catenin.

1996 • 221 citations

Microallelotyping defines the sequence and tempo of alleiic losses at tumour suppressor gene loci during colorectal cancer progression

1995 • 195 citations

Extensive Alternative Splicing and Dual Promoter Usage Generate Tcf-1 Protein Isoforms with Differential Transcription Control Properties

1996 • 193 citations

Alteration of beta-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients.

1996 • 174 citations

Reciprocity between membranous and nuclear expression of β-catenin in colorectal tumours

1997 • 116 citations

APC EXPRESSION IN NORMAL HUMAN TISSUES

1997 • 103 citations

The Role of the Adenomatous Polyposis Coli (Apc) Gene in Human Cancers

1993 • 74 citations

CA repeat polymorphism at the D5S299 locus linked to adenomatous polyposis coli (APC)

1991 • 52 citations

CA repeat polymorphism at the D5S82 locus, proximal to adenomatous polyposis coli (APC)

1991 • 51 citations

A CA-repeat polymorphism close to the adenomatous polyposis coli (APC) gene offers improved diagnostic testing for familial APC.

1993 • 50 citations

Wingless‐type frizzled protein receptor signaling and its putative role in human colon cancer

2001 • 45 citations

Allele loss in colorectal cancer at the Cowden disease/Juvenile Polyposis locus on 10q

1997 • 36 citations

A common ancestor of the mammalian transcription factors TCF‐1 and TCF‐1α/LEF‐1 expressed in chicken T cells

1992 • 29 citations

Differential formation of beta-catenin/lymphoid enhancer factor-1 DNA binding complex induced by nitric oxide in mouse colonic epithelial cells differing in adenomatous polyposis coli (Apc) genotype.

2000 • 15 citations

A gene family of HMG box factors with homology to TCF-1

1992 • 4 citations

Deleted Work

1955 • 0 citations