Neurosecretory control of aging in Caenorhabditis elegans

THE GENETICS OF CAENORHABDITIS ELEGANS

1974 • 14,589 citations

A C. elegans mutant that lives twice as long as wild type

1993 • 3,250 citations

daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

1997 • 2,174 citations

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1997 • 1,905 citations

daf-16 : An HNF-3/forkhead Family Member That Can Function to Double the Life-Span of Caenorhabditis elegans

1997 • 1,468 citations

The genetics of caloric restriction in Caenorhabditis elegans

1998 • 918 citations

The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans

1975 • 881 citations

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

1996 • 870 citations

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

1998 • 680 citations

The Caenorhabditis elegans dauer larva: Developmental effects of pheromone, food, and temperature

1984 • 594 citations

Genes that regulate both development and longevity in Caenorhabditis elegans.

1995 • 579 citations

Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin

1993 • 551 citations

A genetic selection for Caenorhabditis elegans synaptic transmission mutants.

1996 • 449 citations

The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans.

1995 • 442 citations

daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans.

1994 • 375 citations

Cell Nonautonomy of C. elegans daf-2 Function in the Regulation of Diapause and Life Span

1998 • 362 citations

Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans.

1992 • 348 citations

The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine

1998 • 323 citations

Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants.

1998 • 266 citations

Evidence for parallel processing of sensory information controlling dauer formation in Caenorhabditis elegans.

1993 • 262 citations

A novel 145 kd brain cytosolic protein reconstitutes Ca2+-regulated secretion in permeable neuroendocrine cells

1992 • 261 citations

Synaptic Transmission Deficits inCaenorhabditis elegansSynaptobrevin Mutants

1998 • 235 citations

The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development.

1994 • 228 citations

TheCaenorhabditis elegans unc-64Locus Encodes a Syntaxin That Interacts Genetically with Synaptobrevin

1998 • 223 citations

A pheromone-induced developmental switch in Caenorhabditis elegans: Temperature-sensitive mutants reveal a wild-type temperature-dependent process.

1984 • 210 citations

Novel Ca2+-binding Protein (CAPS) Related to UNC-31 Required for Ca2+-activated Exocytosis

1997 • 178 citations

aex-3 Encodes a Novel Regulator of Presynaptic Activity in C. elegans

1997 • 156 citations

The Caenorhabditis elegans unc-31 gene affects multiple nervous system-controlled functions.

1993 • 137 citations

Functional Properties of the unc-64 Gene Encoding aCaenorhabditis elegans Syntaxin

1998 • 77 citations