The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

A C. elegans mutant that lives twice as long as wild type

1993 • 3,250 citations

daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

1997 • 2,174 citations

Signalling through the lipid products of phosphoinositide-3-OH kinase

1997 • 1,314 citations

Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

1993 • 1,269 citations

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

1993 • 884 citations

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

1996 • 870 citations

Aging and resistance to oxidative damage in Caenorhabditis elegans.

1993 • 720 citations

A transcriptional partner for MAD proteins in TGF-β signalling

1996 • 699 citations

Genes that regulate both development and longevity in Caenorhabditis elegans.

1995 • 579 citations

Control of C. elegans Larval Development by Neuronal Expression of a TGF-β Homolog

1996 • 516 citations

Interacting genes in nematode dauer larva formation

1981 • 504 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally.

1990 • 466 citations

Genetic and Environmental Regulation of Dauer Larva Development

1997 • 446 citations

The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans.

1995 • 442 citations

A Pheromone Influences Larval Development in the Nematode Caenorhabditis elegans

1982 • 404 citations

daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans.

1994 • 375 citations

The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development

1993 • 368 citations

Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans.

1992 • 348 citations

The PAX3-FKHR Fusion Protein Created by the t(2;13) Translocation in Alveolar Rhabdomyosarcomas Is A More Potent Transcriptional Activator than PAX3

1995 • 304 citations

daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase

1990 • 293 citations

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

1997 • 247 citations

Hepatic Nuclear Factor 3- and Hormone-Regulated Expression of the Phosphoenolpyruvate Carboxykinase and Insulin-Like Growth Factor-Binding Protein 1 Genes

1995 • 226 citations

In vivo treatment with antibody against IGF-1 receptor suppresses growth of human rhabdomyosarcoma and down-regulates p34cdc2.

1994 • 186 citations

Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma.

1994 • 170 citations

lin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulval development.

1993 • 167 citations

Overexpression of a Constitutively Active Form of Phosphatidylinositol 3-Kinase Is Sufficient to Promote Glut 4 Translocation in Adipocytes

1996 • 158 citations

DNA recognition site analysis of Xenopus wingedhelix proteins

1995 • 86 citations

A case of alveolar rhabdomyosarcoma with a chromosomal translocation, t(2; 13) (q37; q14)

1990 • 11 citations