ARA,a Novel ABC Transporter, Is Located at 16p13.1, Is Deleted in inv(16) Leukemias, and Is Shown To Be Expressed in Primitive Hematopoietic Precursors

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

1997 • 889 citations

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

1994 • 777 citations

Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia

1993 • 760 citations

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

1994 • 635 citations

Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAJ) gene in liver

1997 • 269 citations

Mapping the whole human genome by fingerprinting yeast artificial chromosomes

1992 • 161 citations

Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell.

1995 • 145 citations

Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1.

1996 • 106 citations

Deletion of gene for multidrug resistance in acute myeloid leukaemia with inversion in chromosome 16: prognostic implications

1994 • 105 citations

An integrated physical map of human chromosome 16.

1995 • 94 citations

Molecular characterization of 16p deletions associated with inversion 16 defines the critical fusion for leukemogenesis

1995 • 91 citations

Reassessment of two apparent deletions of chromosome 16p to an ins(11;16) and a t(1;16) by chromosome painting.

1990 • 87 citations

Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance‐associated protein

1996 • 75 citations

The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line

1996 • 64 citations

Integration of Transcript and Genetic Maps of Chromosome 16 at Near-1-Mb Resolution: Demonstration of a “Hot Spot” for Recombination at 16p12

1995 • 45 citations

Cloning the breakpoint cluster region of the inv(16) in acute nonlymphocytic leukemia M4 Eo

1993 • 45 citations

The biological significance of the multidrug resistance gene MRP in inversion 16 leukemias

1996 • 16 citations