The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

ABC Transporters: From Microorganisms to Man

1992 • 3,956 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia

1965 • 1,213 citations

Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

1993 • 1,175 citations

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

1994 • 850 citations

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

1994 • 777 citations

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1994 • 621 citations

ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

1994 • 435 citations

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

1992 • 407 citations

The Leukotriene LTD4 Receptor Antagonist Mk571 Specifically Modulates MRP Associated Multidrug Resistance

1995 • 402 citations

A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein.

1994 • 364 citations

Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines

1994 • 315 citations

The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein.

1993 • 297 citations

Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies.

1994 • 284 citations

Binding protein-dependent transport systems

1990 • 272 citations

DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing

1992 • 161 citations

P-glycoprotein as multidrug transporter: a critical review of current multidrug resistant cell lines

1992 • 157 citations

Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein

1993 • 147 citations

Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell.

1995 • 145 citations

A 190-Kilodalton Protein Overexpressed in Non-P-Glycoprotein-Containing Multidrug-Resistant Cells and Its Relationship to the MRP Gene

1994 • 143 citations

P-glycoproteins: mediators of multidrug resistance

1993 • 143 citations

Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells

1994 • 113 citations

RNA isolation: a mini-prep method

1988 • 93 citations

Buthionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulation

1995 • 85 citations

Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a member of ATP-binding cassette transporters

1992 • 82 citations

Drug resistance mechanisms and MRP expression in response to epirubicin treatment in a human leukaemia cell line

1995 • 68 citations

Analysis of MRP gene expression and function in HL60 cells isolated for resistance to adriamycin.

1994 • 60 citations

The role of glutathione biosynthesis in heavy metal resistance in the fission yeastSchizosaccharomyces pombe

1994 • 55 citations

MRP gene overexpression in a human doxorubicin-resistant SCLC cell line: Alterations in cellular pharmacokinetics and in pattern of cross-resistance

1995 • 42 citations

Characterization of a Novel Schizosaccharomyces pombe Multidrug Resistance Transporter Conferring Brefeldin A Resistance

1995 • 32 citations

Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells

1995 • 8 citations

The role of glutathione biosynthesis in heavy metal resistance in the fission yeast Schizosaccharomyces pombe

1994 • 6 citations

MRP gene overexpression in a human doxorubicin-resistant SCLC cell line: Alterations in cellular pharmacokinetics and in pattern of cross-resistance

1995 • 1 citations