The Adaptor Complex 2 Directly Interacts with the α1b-Adrenergic Receptor and Plays a Role in Receptor Endocytosis

Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling.

2001 • 1,794 citations

β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

1996 • 1,329 citations

Interaction of Tyrosine-Based Sorting Signals with Clathrin-Associated Proteins

1995 • 955 citations

Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization

1996 • 938 citations

The β ₂ -adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

1999 • 615 citations

Molecular Architecture and Functional Model of the Endocytic AP2 Complex

2002 • 601 citations

A Structural Explanation for the Recognition of Tyrosine-Based Endocytotic Signals

1998 • 582 citations

Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.

1988 • 566 citations

Adaptor-related proteins

2001 • 531 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Regulation of G Protein-Coupled Receptor Kinases and Arrestins During Receptor Desensitization

2003 • 440 citations

Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site

1998 • 310 citations

Arresting developments in heptahelical receptor signaling and regulation

2002 • 225 citations

AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells

2002 • 211 citations

Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.

1987 • 206 citations

Differential Roles of Arrestin-2 Interaction with Clathrin and Adaptor Protein 2 in G Protein-coupled Receptor Trafficking

2002 • 189 citations

Delineation of the Oligomerization, AP-2 Binding, and Synprint Binding Region of the C2B Domain of Synaptotagmin

1998 • 180 citations

Effect of Different G Protein-coupled Receptor Kinases on Phosphorylation and Desensitization of the α1B-Adrenergic Receptor

1996 • 175 citations

Epidermal Growth Factor Receptor Interaction with Clathrin Adaptors Is Mediated by the Tyr974-containing Internalization Motif

1996 • 167 citations

Polarized trafficking and surface expression of the AQP4 water channel are coordinated by serial and regulated interactions with different clathrin-adaptor complexes

2001 • 158 citations

β-Arrestin/AP-2 Interaction in G Protein-coupled Receptor Internalization

2002 • 143 citations

Dual interaction of synaptotagmin with micro2- and alpha-adaptin facilitates clathrin-coated pit nucleation

2000 • 132 citations

Truncation of the receptor carboxyl terminus impairs agonist-dependent phosphorylation and desensitization of the alpha 1B-adrenergic receptor.

1994 • 132 citations

Characterization of the Phosphorylation Sites Involved in G Protein-coupled Receptor Kinase- and Protein Kinase C-mediated Desensitization of the α1B-Adrenergic Receptor

1997 • 123 citations

Clathrin coat construction in endocytosis

2000 • 116 citations

Medium Chains of Adaptor Complexes AP-1 and AP-2 Recognize Leucine-based Sorting Signals from the Invariant Chain

1998 • 104 citations

Agonist Regulation of α1B-Adrenergic Receptor Subcellular Distribution and Function

1995 • 95 citations

Constitutively ActiveAlpha-1b Adrenergic Receptor Mutants Display Different Phosphorylation and Internalization Features

1999 • 73 citations

μ2 Binding Directs the Cystic Fibrosis Transmembrane Conductance Regulator to the Clathrin-mediated Endocytic Pathway

2001 • 49 citations

Co- and Posttranslational Modification of the α_1B-Adrenergic Receptor: Effects on Receptor Expression and Function

2002 • 16 citations