Immunohistochemical analysis of integrin αvβ3 expression on tumor‐associated vessels of human carcinomas

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1994 • 2,293 citations

Definition of Two Angiogenic Pathways by Distinct α _v Integrins

1995 • 1,333 citations

The role of angiogenesis in tumor growth.

1992 • 1,267 citations

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

1995 • 840 citations

Relation of neovascularisation to metastasis of non-small-cell lung cancer

1992 • 780 citations

Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor.

1987 • 574 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma. A quantitative histologic study.

1988 • 538 citations

Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool.

1995 • 441 citations

Intratumoral microvessel density and L53 protein: Correlation with metastasis in head‐and‐neck squamous‐cell carcinoma

1993 • 314 citations

Integrins as dynamic regulators of vascular function

1994 • 289 citations

Monoclonal antibody PAL-E specific for endothelium.

1985 • 251 citations

Extracellular matrix and cell shape: Potential control points for inhibition of angiogenesis

1991 • 247 citations

Tumor angiogenesis as a predictor of recurrence in gastric carcinoma.

1995 • 241 citations

Differential expression of markers for endothelial cells, pericytes, and basal lamina in the microvasculature of tumors and granulation tissue.

1991 • 222 citations

Cytokine networks in solid human tumors: regulation of angiogenesis

1994 • 209 citations

Expression and Modulation of the Vitronectin Receptor on Human Dermal Microvascular Endothelial Cells

1992 • 70 citations

In situ expression of ?1, ?3 and ?4 integrin subunits in non-neoplastic endothelium and vascular tumours

1994 • 30 citations