A Critical Role for Tapasin in the Assembly and Function of Multimeric MHC Class I-TAP Complexes

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

1990 • 918 citations

Roles for Calreticulin and a Novel Glycoprotein, Tapasin, in the Interaction of MHC Class I Molecules with TAP

1996 • 697 citations

Codon usage patterns inEscherichia coli, Bacillus subtilis, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Drosophila melanogasterandHomo sapiens; a review of the considerable within-species diversity

1988 • 584 citations

T–cell mediated rejection of gene–modified HIV–specific cytotoxic T lymphocytes in HIV–infected patients

1996 • 581 citations

Proteolysis, proteasomes and antigen presentation

1992 • 576 citations

HLA-A2.1-Associated Peptides from a Mutant Cell Line: A Second Pathway of Antigen Presentation

1992 • 522 citations

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

1992 • 502 citations

Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus.

1994 • 447 citations

MHC class l/β2-microglobulin complexes associate with TAP transporters before peptide binding

1994 • 356 citations

Interaction of MHC Class I Molecules with the Transporter Associated with Antigen Processing

1994 • 300 citations

A sequential model for peptide binding and transport by the transporters associated with antigen processing

1994 • 290 citations

The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation

1997 • 274 citations

Membrane protein association by potential intrarnembrane charge pairs

1991 • 239 citations

Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules

1992 • 215 citations

HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules

1996 • 206 citations

Functional expression and purification of the ABC transporter complex associated with antigen processing (TAP) in insect cells

1994 • 201 citations

Dependence of Peptide Binding by MHC Class I Molecules on Their Interaction with TAP

1995 • 189 citations

The peptide-binding motif for the human transporter associated with antigen processing.

1995 • 186 citations

Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing.

1996 • 174 citations

Structural requirements of a membrane-spanning domain for protein anchoring and cell surface transport

1985 • 173 citations

Species-specific differences in chaperone interaction of human and mouse major histocompatibility complex class I molecules.

1995 • 157 citations

Characteristics of peptide and major histocompatibility complex class I/beta 2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2).

1994 • 150 citations

Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum.

1996 • 146 citations

Novel allele-specific, post-translational reduction in HLA class I surface expression in a mutant human B cell line.

1994 • 136 citations

Prominence of beta 2-microglobulin, class I heavy chain conformation, and tapasin in the interactions of class I heavy chain with calreticulin and the transporter associated with antigen processing.

1997 • 132 citations

Supply and transport of peptides presented by class I MHC molecules

1995 • 91 citations

Deglucosylation of N-linked glycans is an important step in the dissociation of calreticulin–class I–TAP complexes

1996 • 81 citations

The human homologue of the mouse t-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region.

1987 • 74 citations

Characteristics of peptide and class I/b2m binding to the transporters associated with antigen processing (TAP. 1 and TAP. 2)

1994 • 59 citations

Fine mapping of the human MHC class II region within chromosome band 6p21 and evaluation of probe ordering using interphase fluorescence in situ hybridization

1993 • 55 citations

[30] Significance of protein sequence similarities

1990 • 49 citations

An epitope common to HLA class I and class II antigens, Ig light chains, and ? 2-microglobulin

1987 • 38 citations

Localization of the Human CRF2 Receptor to 7p21–p15 by Radiation Hybrid Mapping and FISH Analysis

1997 • 34 citations