Regulation of the differentiation of PC12 pheochromocytoma cells.

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Multiple Calcium Channels and Neuronal Function

1987 • 1,336 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo

1951 • 947 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

THE NERVE GROWTH FACTOR: PURIFICATION AS A 30,000-MOLECULAR-WEIGHT PROTEIN

1969 • 920 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1985 • 738 citations

PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM

1960 • 692 citations

Destruction of the sympathetic ganglia in mammals by an antiserum to a nerve-growth protein

1960 • 651 citations

Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells.

1979 • 627 citations

Expression of the beta-nerve growth factor gene correlates with the density of sympathetic innervation in effector organs.

1984 • 519 citations

Dorsal Root Ganglion Neurons Are Destroyed by Exposure in Utero to Maternal Antibody to Nerve Growth Factor

1980 • 500 citations

Nerve growth factor increases choline acetyl-transferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neurons

1985 • 491 citations

Human β-nerve growth factor gene sequence highly homologous to that of mouse

1983 • 486 citations

Choline Acetyltransferase Activity in Striatum of Neonatal Rats Increased by Nerve Growth Factor

1985 • 483 citations

Superinduction of c- fos by Nerve Growth Factor in the Presence of Peripherally Active Benzodiazepines

1985 • 478 citations

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor

1983 • 474 citations

Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids.

1978 • 468 citations

Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

1985 • 458 citations

Th molecular organization of adrenal chromaffin granules

1980 • 455 citations

In Vitro Experiments on the Effects of Mouse Sarcomas 180 and 37 on the Spinal and Sympathetic Ganglia of the Chick Embryo

1997 • 449 citations

Gene Transfer and Molecular Cloning of the Human NGF Receptor

1986 • 447 citations

PRIMARY CULTURES OF DISSOCIATED SYMPATHETIC NEURONS

1973 • 426 citations

Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21

1986 • 421 citations

Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheochromocytoma cells

1977 • 410 citations

Nerve growth factor-induced increase in electrical excitability and acetylcholine sensitivity of a rat pheochromocytoma cell line

1977 • 395 citations

The Isolation of the Mouse Nerve Growth Factor Protein in a High Molecular Weight Form^*

1967 • 372 citations

Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues.

1984 • 359 citations

Induction of the proto-oncogene fos by nerve growth factor.

1985 • 359 citations

Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP.

1987 • 328 citations

K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cells

1988 • 320 citations

Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene

1985 • 306 citations

Nerve growth factor mediates phosphorylation of specific proteins

1980 • 305 citations

Nerve growth factor receptors on PC12 cells: Evidence for two receptor classes with differing cytoskeletal association

1981 • 302 citations

Nerve Growth Factor and Insulin

1972 • 283 citations

PC12 cell mutants that possess low- but not high-affinity nerve growth factor receptors neither respond to nor internalize nerve growth factor.

1986 • 282 citations

Tetanus toxin: a cell surface marker for neurones in culture

1978 • 280 citations

Molecular Cloning of a Gene Sequence Regulated by Nerve Growth Factor

1985 • 279 citations

Alterations in the surface properties of cells responsive to nerve growth factor

1978 • 279 citations

The effect of fibroblast growth factor on PC12 cells

1985 • 270 citations

Implantation of tumors in the hind limb field of the embryonic chick and the developmental response of the lumbosacral nervous system

1948 • 263 citations

Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor

1981 • 262 citations

Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low- to high-affinity states.

1980 • 255 citations

Synthesis, storage and release of acetylcholine by a noradrenergic pheochromocytoma cell line

1977 • 252 citations

Gangliosides enhance neurite outgrowth in PC12 cells

1983 • 249 citations

Nerve growth factor promotes cholinergic development in brain striatal cultures.

1985 • 245 citations

Regulation of tyrosine hydroxylase mRNA by glucocorticoid and cyclic AMP in a rat pheochromocytoma cell line. Isolation of a cDNA clone for tyrosine hydroxylase mRNA.

1983 • 243 citations

Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor.

1979 • 225 citations

Evidence for RNA synthesis-dependent and -independent pathways in stimulation of neurite outgrowth by nerve growth factor

1978 • 224 citations

Nerve growth factor rapidly induces c-fos mRNA in PC12 rat pheochromocytoma cells.

1986 • 220 citations

Cholinergic metabolism and synapse formation by a rat nerve cell line.

1977 • 217 citations

Reversible dissociation of the mouse nerve growth factor protein into different subunits

1968 • 210 citations

alpha-Bungarotoxin binding and cholinergic receptor function on a rat sympathetic nerve line

1977 • 210 citations

Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor.

1983 • 207 citations

Morphologic and cytochemical properties of a clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1978 • 200 citations

Immunological distinction between acetylcholine receptor and the alpha-bungarotoxin-binding component on sympathetic neurons.

1977 • 199 citations

Ethanol regulates calcium channels in clonal neural cells.

1986 • 197 citations

Association of 125I-nerve growth factor with PC12 pheochromocytoma cells. Evidence for internalization via high-affinity receptors only and for long-term regulation by nerve growth factor of both high- and low-affinity receptors.

1984 • 197 citations

Protein kinase C as a component of a nerve growth factor-sensitive phosphorylation system in PC12 cells.

1986 • 197 citations

Nerve growth factor-mediated stimulation of tyrosine hydroxylase activity in a clonal rat pheochromocytoma cell line

1981 • 194 citations

Alteration of cellular adhesion by nerve growth factor.

1977 • 193 citations

Nerve growth factor in the nucleus: interaction with receptors on the nuclear membrane.

1979 • 191 citations

Tumor promoter phorbol myristate acetate inhibits Ca2+ influx through voltage-gated Ca2+ channels in two secretory cell lines, PC12 and RINm5F.

1986 • 178 citations

Regulation of neural cell adhesion molecule expression on cultured mouse Schwann cells by nerve growth factor.

1987 • 177 citations

NGF stimulates incorporation of fucose or glucosamine into an external glycoprotein in cultured rat PC12 pheochromocytoma cells

1978 • 172 citations

Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases.

1986 • 169 citations

Heparin modulation of the neurotropic effects of acidic and basic fibroblast growth factors and nerve growth factor on PC12 cells

1987 • 163 citations

The role of cAMP in nerve growth factor-promoted neurite outgrowth in PC12 cells.

1986 • 161 citations

A single Mr approximately 103,000 125I-beta-nerve growth factor-affinity-labeled species represents both the low and high affinity forms of the nerve growth factor receptor.

1986 • 159 citations

Regulation of microtubule composition and stability during nerve growth factor-promoted neurite outgrowth.

1986 • 154 citations

Sodium and calcium fluxes in a clonal nerve cell line.

1979 • 152 citations

Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells.

1983 • 150 citations

Ca²⁺/calmodulin‐dependent phosphorylation of elongation factor 2

1987 • 150 citations

Activated N‐ras gene induces neuronal differentiation of PC12 rat pheochromocytoma cells

1986 • 149 citations

Rapid, sequential changes in surface morphology of PC12 pheochromocytoma cells in response to nerve growth factor

1979 • 146 citations

?- and ?-receptor control of catecholamine secretion from isolated adrenal medulla cells

1982 • 143 citations

Release of [3H]norepinephrine from a clonal line of pheochromocytoma cells (PC12) by nicotinic cholinergic stimulation

1977 • 141 citations

Mobility, clustering, and transport of nerve growth factor in embryonal sensory cells and in a sympathetic neuronal cell line.

1980 • 140 citations

Nerve growth factor enhances expression of neuron-glia cell adhesion molecule in PC12 cells.

1986 • 139 citations

Identification of a nerve growth factor receptor protein in sympathetic ganglia membranes by affinity labeling.

1981 • 133 citations

Increased phosphorylation of specific nuclear proteins in superior cervical ganglia and PC12 cells in response to nerve growth factor.

1980 • 132 citations

A second messenger required for nerve growth factor biological activity?

1981 • 132 citations

Demonstration of immunochemical identity between the nerve growth factor-inducible large external (NILE) glycoprotein and the cell adhesion molecule L1.

1985 • 131 citations

Calcium-Dependent Nerve Growth Factor-Stimulated Hydrolysis of Phosphoinositides in PC12 Cells

1987 • 127 citations

Nerve growth factor and other agents mediate phosphorylation and activation of tyrosine hydroxylase. A convergence of multiple kinase activities.

1985 • 124 citations

Selective enzyme induction in a nerve growth factor-responsive pheochromocytoma cell line (PC 12)

1978 • 122 citations

Storage and release of acetylcholine by a clonal cell line.

1977 • 118 citations

Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists.

1985 • 113 citations

EFFECTS OF A NERVE‐GROWTH FACTOR, EMBRYO AGE AND METABOLIC INHIBITORS ON GROWTH OF FIBRES AND ON SYNTHESIS OF RIBONUCLEIC ACID AND PROTEIN IN EMBRYONIC SYMPATHETIC GANGLIA¹

1971 • 111 citations

Induction of ornithine decarboxylase by nerve growth factor dissociated from effects on survival and neurite outgrowth

1978 • 109 citations

The modulation of neurotransmitter synthesis by steroid hormones and insulin

1980 • 109 citations

The effects of nerve growth factor on acetylcholinesterase and its multiple forms in cultures of rat PC12 pheochromocytoma cells: Increased total specific activity and appearance of the 16 S molecular form

1980 • 108 citations

Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell line

1980 • 107 citations

Nerve growth factor-inducible large external (NILE) glycoprotein: studies of a central and peripheral neuronal marker

1983 • 106 citations

Neurite outgrowth and protein synthesis by PC12 cells as a function of substratum and nerve growth factor

1982 • 106 citations

Differential regulation of peptide and catecholamine characters in cultured sympathetic neurons

1985 • 104 citations

Purification of the receptor for nerve growth factor from A875 melanoma cells by affinity chromatography.

1983 • 104 citations

Nerve growth factor has both mitogenic and antimitogenic activity

1982 • 103 citations

Modulation of protein synthesis by nerve growth factor.

1979 • 102 citations

Differential inhibition of nerve growth factor and epidermal growth factor effects on the PC12 pheochromocytoma line.

1984 • 102 citations

Isolation of human nerve growth factor from placental tissue

1978 • 101 citations

The Distribution of Nerve Growth Factor in the Male Sex Organs of Mammals

1980 • 101 citations

The action of nerve growth factor and dibutyryl adenosine cyclic 3':5'- monophosphate on rat pheochromocytoma reveals distinct stages in the mechanisms underlying neurite outgrowth

1981 • 101 citations

Neuritic growth from a new subline of PC12 pheochromocytoma cells: Cyclic AMP mimics the action of nerve growth factor

1987 • 100 citations

Nerve growth factor rapidly induces ornithine decarboxylase mRNA in PC12 rat pheochromocytoma cells.

1985 • 99 citations

Voltage-dependent activation and inactivation of calcium channels in PC12 cells. Correlation with neurotransmitter release.

1987 • 98 citations

The internalization of nerve growth factor by high-affinity receptors on pheochromocytoma PC12 cells.

1987 • 98 citations

Alterations of Lipid Metabolism in Response to Nerve Growth Factor

1982 • 97 citations

Functional acetylcholine receptor in PC12 cells reacts with a monoclonal antibody to brain nicotinic receptors

1987 • 93 citations

Interaction of GM1 ganglioside with PC12 pheochromocytoma cells: Serum‐ and NGF‐dependent effects on neuritic growth (and proliferation)

1984 • 93 citations

Nerve growth factor-induced increase in the cell-free phosphorylation of a nuclear protein in PC12 cells.

1985 • 92 citations

Purification and mechanism of activation of a nerve growth factor-sensitive S6 kinase from PC12 cells.

1987 • 92 citations

The Action of Adenosine Analogs on PC12 Cells

1981 • 91 citations

Early rise of cytosolic Ca²⁺ induced by NGF in PC12 and chromaffin cells

1986 • 89 citations

Cell-free detection and characterization of a novel nerve growth factor-activated protein kinase in PC12 cells.

1987 • 88 citations

Nerve growth factor increases the number of functional Na channels and induces TTX-resistant Na channels in PC12 pheochromocytoma cells

1987 • 88 citations

Regulation of protein kinase activities in PC12 pheochromocytoma cells.

1986 • 88 citations

Possible muscarinic regulation of catecholamine secretion mediated by cyclic GMP in isolated bovine adrenal chromaffin cells

1981 • 87 citations

Purification, characterization, and partial amino acid sequence of nerve growth factor from cobra venom

1976 • 87 citations

Properties of the nerve growth factor receptor of a clonal line of rat pheochromocytoma (PC12) cells

1979 • 86 citations

Clonal variants of PC12 pheochromocytoma cells with altered response to nerve growth factor

1980 • 85 citations

Nerve growth factor‐mediated selective induction of ornithine decarboxylase in rat pheochromocytoma; a cyclic amp‐independent process

1978 • 85 citations

Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.

1986 • 84 citations

Nerve growth factor-induced reduction in epidermal growth factor responsiveness and epidermal growth factor receptors in PC12 cells: An aspect of cell differentiation

1979 • 84 citations

Protein kinase C mediated regulation of calcium channels in PC-12 pheochromocytoma cells

1986 • 84 citations

Nerve growth factor- and epidermal growth factor-stimulated phosphorylation of a PC12 cytoskeletally associated protein in situ.

1985 • 83 citations

Regulation of acetylcholinesterase activity by nerve growth factor. Role of transcription and dissociation from effects on proliferation and neurite outgrowth.

1981 • 80 citations

SHORT‐TERM REGULATION OF CATECHOLAMINE BIOSYNTHESIS IN A NERVE GROWTH FACTOR RESPONSIVE CLONAL LINE OF RAT PHEOCHROMOCYTOMA CELLS

1978 • 79 citations

Rapid stimulation by nerve growth factor of amino acid uptake by clonal PC12 pheochromocytoma cells.

1979 • 79 citations

Gangliosides stimulate neurite outgrowth and induce tubulin mRNA accumulation in neural cells

1983 • 79 citations

Phosphorylation of nerve growth factor receptor proteins in sympathetic neurons and PC12 cells. In vitro phosphorylation by the cAMP-independent protein kinase FA/GSK-3.

1986 • 78 citations

PC12 adhesion and neurite formation on selected substrates are inhibited by some glycosaminoglycans and a fibronectin-derived tetrapeptide

1986 • 77 citations

Magnesium-dependent attachment and neurite outgrowth by PC12 cells on collagen and laminin substrata

1987 • 77 citations

Nerve growth factor enhances the synthesis, phosphorylation, and metabolic stability of neurofilament proteins in PC12 cells.

1987 • 77 citations

Nerve growth factor-mediated induction of tyrosine hydroxylase and of neurite outgrowth in cultures of bovine adrenal chromaffin cells: Dependence on developmental stage

1982 • 76 citations

Nerve growth factor-induced increase in saxitoxin binding to rat PC12 pheochromocytoma cells

1982 • 75 citations

Co-expression of cytokeratins and neurofilament proteins in a permanent cell line: cultured rat PC12 cells combine neuronal and epithelial features.

1986 • 74 citations

Mechanism of biosynthesis of soluble and membrane-bound forms of dopamine beta-hydroxylase in PC12 pheochromocytoma cells.

1983 • 74 citations

Regulation of muscarinic ligand binding sites by nerve growth factor in PC12 phaeochromocytoma cells

1982 • 74 citations

Changes in the phosphorylation and distribution of vinculin during nerve growth factor induced neurite outgrowth

1987 • 73 citations

Physiological and morphological studies of rat pheochromocytoma cells (PC12) chemically fused and grown in culture.

1980 • 72 citations

Biochemical properties of the nerve growth factor-inducible large external (NILE) glycoprotein

1983 • 72 citations

Relationship between NGF-mediated volume increase and “priming effect” in fast and slow reacting clones of PC12 pheochromocytoma cells

1983 • 70 citations

Short-latency local actions of nerve growth factor at the growth cone.

1983 • 68 citations

Ethanol-induced component of 45Ca2+ uptake in PC12 cells is sensitive to Ca2+ channel modulating drugs

1987 • 67 citations

Pit formation and rapid changes in surface morphology of sympathetic neurons in response to nerve growth factor.

1981 • 67 citations

Activation of muscarinic receptors in PC12 cells. Stimulation of Ca2+ influx and redistribution

1986 • 67 citations

Ca2+ transmembrane fluxes and nerve growth factor action on a clonal cell line of rat phaeochromocytoma

1980 • 66 citations

Chromosomal locations of the human and mouse genes for precursors of epidermal growth factor and the beta subunit of nerve growth factor.

1985 • 65 citations

Binding of nerve growth factor to its receptor

1987 • 65 citations

Neuritogenic and metabolic effects of individual gangliosides and their interaction with nerve growth factor in cultures of neuroblastoma and pheochromocytoma

1986 • 65 citations

Interaction of calmodulin inhibitors and protein kinase C inhibitors with voltage-dependent calcium channels

1987 • 65 citations

Nicotine stimulates secretion of both catecholamines and acetylcholinesterase from cultured adrenal chromaffin cells

1983 • 61 citations

Induction of neurite outgrowth in the IMR‐32 human neuroblastoma cell line by nerve growth factor

1981 • 61 citations

Slow EPSP and the depolarizing action of noradrenaline on sympathetic preganglionic neurons

1987 • 60 citations

Cellular localization of the molecular forms of acetylcholinesterase in rat pheochromocytoma PC12 cells treated with nerve growth factor

1981 • 59 citations

Two types of transglutaminase in the PC12 pheochromocytoma cell line. Stimulation by sodium butyrate.

1987 • 59 citations

Tumor promoter modulation of epidermal growth factor‐ and nerve growth factor‐induced adhesion and growth factor binding of PC‐12 pheochromocytoma cells

1980 • 58 citations

Effects of ethanol on 45Ca2+ uptake in synaptosomes and in PC12 cells

1987 • 58 citations

Nerve growth factor-mediated induction of choline acetyltransferase in PC12 cells: evaluation of the site of action of nerve growth factor and the involvement of lysosomal degradation products of nerve growth factor

1984 • 57 citations

Extracellular matrix derived from astrocytes stimulates neuritic outgrowth from PC12 cells in vitro

1987 • 57 citations

The Induction of Ornithine Decarboxylase by Nerve Growth Factor and Epidermal Growth Factor in PC 12 Cells

1981 • 54 citations

Relationship between activation and phosphorylation of tyrosine hydroxylase by 56 mm K+ in PC12 cells in culture.

1984 • 54 citations

Long-term, heterologous down-regulation of the epidermal growth factor receptor in PC12 cells by nerve growth factor.

1987 • 54 citations

The protein kinase C activator phorbol‐12‐myristate‐13‐acetate enhances cyclic AMP accumulation in pheochromocytoma cells

1986 • 54 citations

Activation of muscarinic receptors in PC12 cells. Correlation between cytosolic Ca2+ rise and phosphoinositide hydrolysis

1986 • 53 citations

Nuclear localization of a lactic dehydrogenase with single-stranded DNA-binding properties

1985 • 53 citations

Synapsin I in PC12 cells. I. Characterization of the phosphoprotein and effect of chronic NGF treatment

1987 • 52 citations

Morphological properties and membrane channels of the growth cones induced in PC12 cells by nerve growth factor

1985 • 52 citations

Two receptor classes for epidermal growth factor on pheochromocytoma cells, distinguishable by temperature, lectins, and tumor promoters

1985 • 51 citations

Nerve growth factor enhances the level of the protein kinase C substrate B-50 in pheochromocytoma PC12 cells

1986 • 48 citations

Nerve growth factor—Recent developments and perspectives

1976 • 48 citations

Regulation of tyrosine hydroxylase phosphorylation in PC12 pheochromocytoma cells by elevated K+ and nerve growth factor. Evidence for different mechanisms of action.

1985 • 48 citations

Partial purification and characterization of a nerve growth factor-sensitive kinase and its substrate from PC12 cells.

1985 • 47 citations

Inhibition of calcium flux and calcium channel antagonist binding in the PC12 neural cell line by phorbol esters and protein kinase C

1986 • 47 citations

Content and release of neurotensin in PC12 pheochromocytoma cell cultures: modulation by dexamethasone and nerve growth factor

1982 • 46 citations

Rapid Activation of Tyrosine Hydroxylase in Response to Nerve Growth Factor

1984 • 46 citations

The heterogeneity of nerve growth factor receptors.

1979 • 45 citations

Neuropeptide Y (NPY) in pc12 phaeochromocytoma cultures: Responses to dexamethasone and nerve growth factor

1984 • 45 citations

Rapid effects of nerve growth factor on the Na+,K+-pump in rat pheochromocytoma cells

1981 • 44 citations

Synapsin I in PC12 cells. II. Evidence for regulation by NGF of phosphorylation at a novel site

1987 • 44 citations

N6-Substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors

1986 • 44 citations

Enkephalin and substance p modulate synaptic properties of chick ciliary ganglion neurons in cell culture

1986 • 43 citations

Nerve growth factor induces specific enkephalin binding sites in a nerve cell line.

1982 • 43 citations

.beta. Nerve growth factor binding to PC12 cells. Association kinetics and cooperative interactions

1986 • 43 citations

Properties of the apamin-sensitive Ca2+-activated K+ channel in PC12 pheochromocytoma cells which hyper-produce the apamin receptor.

1986 • 42 citations

Cooperative regulation of neurotensin content in PC12 pheochromocytoma cell cultures: effects of nerve growth factor, dexamethasone, and activators of adenylate cyclase

1986 • 41 citations

Conversion of nerve growth factor-receptor complexes to a slowly dissociating, Triton X-100 insoluble state by anti nerve growth factor antibodies

1983 • 40 citations

Effects of 12‐0‐tetradecanoylphorbol‐13‐acetate (TPA) on rat pheochromocytoma (PC12) cells: Interactions with epidermal growth factor and nerve growth factor

1982 • 39 citations

Cell surface Thy-1-cross-reactive glycoprotein in cultured PC12 cells: modulation by nerve growth factor and association with the cytoskeleton

1985 • 39 citations

Nerve growth factor-mediated induction of tyrosine hydroxylase in a clonal pheochromocytoma cell line.

1978 • 38 citations

Epidermal growth factor receptor expression during morphological differentiation of pheochromocytoma cells, induced by nerve growth factor or dibutyryl cyclic AMP

1987 • 38 citations

Characterization of Adenosine Receptors in the PC 12 Pheochromocytoma Cell Line Using Radioligand Binding: Evidence for A‐2 Selectivity

1987 • 38 citations

Differentiation of PC12 pheochromocytoma cells by sodium butyrate

1987 • 38 citations

Regulation of Nerve Growth Factor Action on Nsp100 Phosphorylation in PC12h Cells by Calcium

1986 • 37 citations

Isolation and partial amino acid sequence analysis of nerve growth factor from the guinea pig prostate

1981 • 36 citations

Characterization of antisera raised against cultured rat sympathetic neurons

1980 • 36 citations

PC12 Variants Deficient in Catecholamine Transport

1986 • 35 citations

Regulation of acetylcholinesterase by nerve growth factor in the pheochromocytoma PC12 cell line

1980 • 34 citations

Regulation of the multiple forms of dopamine beta-hydroxylase by nerve growth factor, dexamethasone, and dibutyryl cyclic AMP in the PC12 pheochromocytoma cell line.

1983 • 33 citations

The cultured chromaffin cell: a model for the study of biology and pharmacology of paraneurones

1982 • 32 citations

Decreased levels of nerve growth factor receptor on dexamethasone‐treated PC12 cells

1988 • 32 citations

The effect of nerve growth factor on undifferentiated glioma cells

1980 • 32 citations

Somatostatin-like immunoreactivity is expressed in neural crest cultures

1984 • 32 citations

Increased Levels of Neuron‐Specific Enolase in PC 12 Pheochromocytoma Cells as a Result of Nerve Growth Factor Treatment

1982 • 32 citations

PC12 neurite regeneration and long-term maintenance in the absence of exogenous nerve growth factor in response to contact with Schwann cells

1985 • 31 citations

Epinephrine synthesis in the PC12 pheochromocytoma cell line

1986 • 30 citations

Probable Identity of NILE Glycoprotein and the High‐Molecular‐Weight Component of L1 Antigen

1986 • 29 citations

Atypical Distribution of Asymmetric Acetylcholinesterase in Mutant PC12 Pheochromocytoma Cells Lacking a Cell Surface Heparan Sulfate Proteoglycan

1985 • 28 citations

Synthesis and content of a DNA-binding protein with lactic dehydrogenase activity are reduced by nerve growth factor in the neoplastic cell line PC12

1985 • 27 citations

Characterization of substance P and somatostatin receptors on adrenal chromaffin cells using structural analogues

1982 • 27 citations

Phospholipases elevate cyclic AMP levels and promote neurite extension in a clonal nerve cell line.

1984 • 27 citations

Clonal Variants of PC12 Pheochromocytoma Cells with Defects in cAMP-Dependent Protein Kinases Induce Ornithine Decarboxylase in Response to Nerve Growth Factor but not to Adenosine Agonists

1985 • 27 citations

Comparison of pheochromocytes with ganglion cells and neuroblasts grown in vitro.An electron microscopic and histochemical study

1971 • 25 citations

Pharmacological profile of adenosine A2 receptor in PC12 cells

1986 • 25 citations

Peripheral-type benzodiazepines influence ornithine decarboxylase levels and neurite outgrowth in PC12 cells.

1985 • 24 citations

Nerve growth factor influences sodium ion extrusion from chick embryonic dorsal root ganglionic neurons

1979 • 23 citations

Control of Thy‐1 Glycoprotein Expression in Cultures of PC12 Cells

1987 • 20 citations

TETANUS TOXIN - CELL-SURFACE MARKER FOR NEURONS IN CULTURE

1978 • 20 citations

Nerve growth factor does not activate Na⁺/H⁺ exchange in PC12 pheochromocytoma cells

1985 • 20 citations

Adenosine-dependent activation of tyrosine hydroxylase is defective in adenosine kinase-deficient PC12 cells.

1984 • 18 citations

Two types of potassium channels in the PC12 cell line

1981 • 16 citations

<b>PLASTICITY OF PHEOCHROMOCYTOMA (PC12) CELLS DEMONSTRATED BY NERVE GROWTH FACTOR OR GLUCOCORTICOID TREATMENT: A CATECHOLAMINE FLUORESCENCE AND ELECTRON MICROSCOPIC </b><b>INVESTIGATION </b>

1981 • 16 citations

Nerve growth factor potentiates the agonist-stimulated accumulation of inositol phosphates in PC-12 pheochromocytoma cells

1987 • 16 citations

Monensin depletes PC12 pheochromocytoma cells of catecholamines and of chromaffin-type granules

1982 • 15 citations

Inactivation of 45Ca2+ uptake by prior depolarization of PC12 cells

1985 • 15 citations

Structural Features of the Nerve Growth Factor Inducible Large External Glycoprotein of PC12 Pheochromocytoma Cells and Brain

1983 • 14 citations

Changes in the Expression of β and Actins During Differentiation of PC 12 Cells

1986 • 14 citations

The effect of nerve growth factor on the development of sodium channels in PC12 cells

1986 • 14 citations

NIF (neurite-inducing factor): a novel peptide inducing neurite formation in PC12 cells

1986 • 14 citations

A possible involvement of cytoplasmic Ca2+ in sodium dependency of neurite outgrowth of rat pheochromocytoma PC12 cells

1983 • 12 citations

Glucocorticoid stimulation of dopamine production in PC12 cells on extracellular matrix and plastic

1987 • 12 citations

Calcium-dependent activation of glycogen phosphorylase in rat pheochromocytoma PC12 cells by nerve growth factor

1986 • 11 citations

A clonal rat pheochromocytoma cell line possesses synthesizing ability of γ-aminobutyric acid together with catecholamine and acetylcholine

1980 • 10 citations

Nerve Growth Factor and Gangliosides Stimulate the Release of Glycoproteins from PC 12 Pheochromocytoma Cells

1986 • 10 citations

Nerve growth factor inhibits the synthesis of a single-stranded DNA binding protein in pheochromocytoma cells (clone PC12).

1984 • 10 citations

Simultaneous visualization of the binding of nerve growth factor and epidermal growth factor to single rat pheochromocytoma (PC12) cells through indirect immunohistofluorescence

1982 • 7 citations

Mutants of PC12 cells with altered cyclic AMP responses.

1984 • 5 citations

Partial purification and characterization of a nerve growth factor-sensitive kinase and its substrate from PC12 cells

1985 • 3 citations

Mutants of PC12 Cells with Altered Cyclic AMP Responses

1984 • 2 citations