Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1982 • 1,398 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1985 • 913 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

PC12 Pheochromocytoma Cultures in Neurobiological Research

1982 • 728 citations

Comparative biochemical properties of normal and activated human ras p21 protein

1984 • 713 citations

Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change

1982 • 706 citations

DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1

1984 • 610 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity

1984 • 539 citations

Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry

1980 • 404 citations

Microinjection of the oncogene form of the human H-ras (t-24) protein results in rapid proliferation of quiescent cells

1984 • 401 citations

Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein

1984 • 379 citations

The Biology and Mechanism of Action of Nerve Growth Factor

1982 • 324 citations

Primary structure of the α-subunit of transducin and its relationship to ras proteins

1985 • 291 citations

Sequence of the Alpha Subunit of Photoreceptor G Protein: Homologies Between Transducin, ras , and Elongation Factors

1985 • 276 citations

Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells.

1981 • 239 citations

Evidence for RNA synthesis-dependent and -independent pathways in stimulation of neurite outgrowth by nerve growth factor

1978 • 224 citations

Cholinergic metabolism and synapse formation by a rat nerve cell line.

1977 • 217 citations

Epidermal growth factor stimulates guanine nucleotide binding activity and phosphorylation of ras oncogene proteins

1984 • 203 citations

Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes

1982 • 179 citations

Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein

1985 • 152 citations

Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus

1982 • 151 citations

Activation of ras genes in human tumors does not affect localization, modification, or nucleotide binding properties of p21

1984 • 144 citations

Purification and Characterization of Human H-ras Proteins Expressed in Escherichia coli

1985 • 101 citations

[48] Fluorescent localization of contractile proteins in tissue culture cells

1982 • 96 citations

Short-latency local actions of nerve growth factor at the growth cone.

1983 • 68 citations

Distribution of flourescently labeled α-actinin in living and fixed fibroblasts

1980 • 56 citations

Purification and characterization of human H-ras proteins expressed in Escherichia coli.

1985 • 53 citations