An Intronic Downstream Enhancer Promotes 3′ Splice Site Usage of a Neural Cell-specific Exon

Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things

1998 • 1,121 citations

Exon Recognition in Vertebrate Splicing

1995 • 1,067 citations

Disruption of Splicing Regulated by a CUG-Binding Protein in Myotonic Dystrophy

1998 • 800 citations

SR proteins and splicing control.

1996 • 668 citations

ALTERNATIVE SPLICING OF PRE-mRNA: Developmental Consequences and Mechanisms of Regulation

1998 • 644 citations

Cloning and domain structure of the mammalian splicing factor U2AF

1992 • 566 citations

Split genes and RNA splicing

1994 • 562 citations

Distinct Binding Specificities and Functions of Higher Eukaryotic Polypyrimidine Tract-Binding Proteins

1995 • 537 citations

Nova-1 Regulates Neuron-Specific Alternative Splicing and Is Essential for Neuronal Viability

2000 • 415 citations

The role of exon sequences in splice site selection.

1993 • 367 citations

A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription.

1991 • 344 citations

Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing.

1991 • 338 citations

Binding of the Drosophila Sex-lethal gene product to the alternative splice site of transformer primary transcript

1990 • 333 citations

A reappraisal of non-consensus mRNA splice sites

1991 • 324 citations

A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.

1997 • 324 citations

The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA

1993 • 309 citations

A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.

1993 • 300 citations

The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.

1996 • 286 citations

Initial splice-site recognition and pairing during pre-mRNA splicing

1996 • 281 citations

U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction.

1997 • 277 citations

hnRNP H Is a Component of a Splicing Enhancer Complex That Activates a c-srcAlternative Exon in Neuronal Cells

1999 • 247 citations

U1 snRNP targets an essential splicing factor, U2AF65, to the 3' splice site by a network of interactions spanning the exon.

1992 • 225 citations

Selection of splice sites in pre-mRNAs with short internal exons.

1991 • 224 citations

The Polypyrimidine Tract Binding Protein Binds Upstream of Neural Cell-Specific c-src Exon N1 To Repress the Splicing of the Intron Downstream

1997 • 214 citations

Chicken nonmuscle myosin heavy chains: differential expression of two mRNAs and evidence for two different polypeptides.

1991 • 211 citations

Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit.

1992 • 203 citations

The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event.

1995 • 194 citations

Control of Alternative Splicing by the Differential Binding of U1 Small Nuclear Ribonucleoprotein Particle

1991 • 191 citations

Activation of c-src neuron-specific splicing by an unusual RNA element in vivo and in vitro

1992 • 171 citations

Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA.

1992 • 157 citations

Synergistic interactions between two distinct elements of a regulated splicing enhancer.

1995 • 156 citations

Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element.

1994 • 150 citations

Does steric interference between splice sites block the splicing of a short c-src neuron-specific exon in non-neuronal cells?

1991 • 146 citations

AT-AC Pre-mRNA Splicing Mechanisms and Conservation of Minor Introns in Voltage-Gated Ion Channel Genes

1999 • 145 citations

A Complex Intronic Splicing Enhancer from the c-src Pre-mRNA Activates Inclusion of a Heterologous Exon

1997 • 133 citations

The SR splicing factors ASF/SF2 and SC35 have antagonistic effects on intronic enhancer-dependent splicing of the beta -tropomyosin alternative exon 6A

1997 • 124 citations

Evidence for inserted sequences in the head region of nonmuscle myosin specific to the nervous system. Cloning of the cDNA encoding the myosin heavy chain-B isoform of vertebrate nonmuscle myosin.

1992 • 121 citations

An intronic (A/U)GGG repeat enhances the splicing of an alternative intron of the chicken β-tropomyosin pre-mRNA

1995 • 116 citations

A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA

1997 • 111 citations

Alternative Splicing of the Fibronectin EIIIB Exon Depends on Specific TGCATG Repeats

1998 • 105 citations

A sequence compilation and comparison of exons that are alternatively spliced in neurons

1994 • 105 citations

Precise branch point mapping and quantification of splicing intermediates

1997 • 90 citations

Cooperation of Pre-mRNA Sequence Elements in Splice Site Selection

1992 • 90 citations

Multiple Interdependent Sequence Elements Control Splicing of a Fibroblast Growth Factor Receptor 2 Alternative Exon

1997 • 86 citations

Neuronal Cell Expression of Inserted Isoforms of Vertebrate Nonmuscle Myosin Heavy Chain II-B

1995 • 74 citations

Neuron-specific Alternative Splicing of Nonmuscle Myosin II Heavy Chain-B Pre-mRNA Requires a Cis-acting Intron Sequence

1996 • 72 citations

Baculovirus Expression of Chicken Nonmuscle Heavy Meromyosin II-B

1996 • 70 citations

Alternative splicing in the neural cell adhesion molecule pre-mRNA: regulation of exon 18 skipping depends on the 5'-splice site.

1991 • 69 citations

The Developmental Consequences of Alternate Splicing in Sex Determination and Differentiation inDrosophila

1995 • 54 citations

Control of alternative pre-mRNA splicing by distributed pentameric repeats

1997 • 53 citations

Muscle-Specific Splicing of a Heterologous Exon Mediated by a Single Muscle-Specific Splicing Enhancer from the Cardiac Troponin T Gene

1998 • 51 citations

Gene dosage affects the cardiac and brain phenotype in nonmuscle myosin II-B–depleted mice

2000 • 44 citations

Regulation of the neuron-specific exon of clathrin light chain B

1999 • 35 citations

RNA lariat debranching enzyme as tool for analyzing RNA structure

1990 • 20 citations

Analysis of YAC clones by pulsed-field gel electrophoresis: Physical mapping of Cu/Zn superoxide dismutase gene locus

1990 • 19 citations

Splice-Junction Elements and Intronic Sequences Regulate Alternative Splicing of the Drosophila Myosin Heavy Chain Gene Transcript

1997 • 15 citations