Endothelial-pericyte interactions in angiogenesis

Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis

1996 • 2,844 citations

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

1997 • 2,136 citations

Polymeric system for dual growth factor delivery

2001 • 1,721 citations

Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

1999 • 1,618 citations

Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors

2000 • 1,372 citations

Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

1999 • 1,248 citations

A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF

1998 • 1,239 citations

Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

2000 • 1,138 citations

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.

1994 • 1,123 citations

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

2002 • 1,088 citations

Lack of Pericytes Leads to Endothelial Hyperplasia and Abnormal Vascular Morphogenesis

2001 • 1,067 citations

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

1995 • 1,020 citations

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

1994 • 984 citations

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

1989 • 914 citations

Defective Angiogenesis in Mice Lacking Endoglin

1999 • 851 citations

Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

2000 • 823 citations

Vascular Dysmorphogenesis Caused by an Activating Mutation in the Receptor Tyrosine Kinase TIE2

1996 • 779 citations

Role of tissue factor in embryonic blood vessel development

1996 • 693 citations

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

1999 • 681 citations

TGF-β Receptor Type II Deficiency Results in Defects of Yolk Sac Hematopoiesis and Vasculogenesis

1996 • 651 citations

Pericytes and the Pathogenesis of Diabetic Retinopathy

2002 • 621 citations

Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells.

1987 • 607 citations

The pericyte—A review

1986 • 563 citations

NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis

2001 • 554 citations

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

2001 • 549 citations

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

2002 • 492 citations

Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system.

1990 • 449 citations

Pericytes: Cell Biology and Pathology

2001 • 442 citations

Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5

1999 • 394 citations

Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy

2002 • 389 citations

Heterogeneity of microvascular pericytes for smooth muscle type alpha-actin.

1991 • 385 citations

Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy

2002 • 378 citations

Pericyte involvement in capillary sprouting during angiogenesis in situ

1992 • 373 citations

The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis

1997 • 365 citations

Developmental roles of platelet‐derived growth factors

2001 • 365 citations

Paracrine PDGF-B/PDGF-Rβ signaling controls mesangial cell development in kidney glomeruli

1998 • 359 citations

Endothelial Cells Modulate the Proliferation of Mural Cell Precursors via Platelet-Derived Growth Factor-BB and Heterotypic Cell Contact

1999 • 338 citations

Embryonic Endothelial Cells Transdifferentiate Into Mesenchymal Cells Expressing Smooth Muscle Actins In Vivo and In Vitro

1997 • 330 citations

Angiogenesis in the Corpus Luteum

2000 • 303 citations

Role of the CNS microvascular pericyte in the blood-brain barrier

1998 • 301 citations

Neural Crest Cell Contribution to the Developing Circulatory System

1998 • 289 citations

Developmental Biology of the Vascular Smooth Muscle Cell: Building a Multilayered Vessel Wall

1999 • 288 citations

Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells

2002 • 279 citations

Development of the mouse retinal vasculature: angiogenesis versus vasculogenesis.

2002 • 271 citations

Diversity Within Pericytes

2000 • 271 citations

Microvascular pericytes: a review of their morphological and functional characteristics.

1991 • 261 citations

Combinatorial effects ofFlk1andTal1on vascular and hematopoietic development in the mouse

2003 • 251 citations

Pericytes as a Supplementary Source of Osteoblasts in Periosteal Osteogenesis

1992 • 250 citations

Stable Expression of Angiopoietin-1 and Other Markers by Cultured Pericytes: Phenotypic Similarities to a Subpopulation of Cells in Maturing Vessels During Later Stages of Angiogenesis In Vivo

2002 • 241 citations

Tumor Vessel Development and Maturation Impose Limits on the Effectiveness of Anti-Vascular Therapy

2003 • 240 citations

Smooth muscle cells and fibroblasts of the coronary arteries derive from epithelial-mesenchymal transformation of the epicardium

1999 • 239 citations

N‐cadherin mediates pericytic‐endothelial interaction during brain angiogenesis in the chicken

2000 • 233 citations

Transcription Profiling of Platelet-Derived Growth Factor-B-Deficient Mouse Embryos Identifies RGS5 as a Novel Marker for Pericytes and Vascular Smooth Muscle Cells

2003 • 230 citations

The versatility of microvascular pericytes: from mesenchyme to smooth muscle?

1993 • 210 citations

TIE1 and TIE2 Receptor Tyrosine Kinases Inversely Regulate Embryonic Angiogenesis by the Mechanism of Intussusceptive Microvascular Growth

1998 • 209 citations

Recent advances in pericyte biology--implications for health and disease.

1991 • 203 citations

Pericyte‐specific expression ofRgs5:implications for PDGF and EDG receptor signaling during vascular maturation

2003 • 197 citations

Analysis of Mural Cell Recruitment to Tumor Vessels

2002 • 181 citations

Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms.

2001 • 165 citations

Pericytes as collagen-producing cells in excessive dermal scarring.

1996 • 157 citations

The Two PDGF Receptors Maintain Conserved Signaling In Vivo despite Divergent Embryological Functions

2001 • 147 citations

Pericyte endothelial gap junctions in human cerebral capillaries

1984 • 143 citations

Pericyte-endothelial relationships in cardiac and skeletal muscle capillaries

1979 • 141 citations

Morphogenesis of the First Blood Vessels

1998 • 138 citations

Fibronectin in the microvasculature: localization in the pericyte-endothelial interstitium

1983 • 137 citations

Role of central nervous system microvascular pericytes in activation of antigen-primed splenic T-lymphocytes

1999 • 135 citations

Control of progenitor cell number by mitogen supply and demand

2001 • 134 citations

PDGFB Regulates the Development of the Labyrinthine Layer of the Mouse Fetal Placenta

1999 • 124 citations

Gene Expression during Vascular Pericyte Differentiation

1999 • 120 citations

Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages

1998 • 117 citations

Angiogenesis in the Bovine Corpus Luteum: An Immunocytochemical and Ultrastructural Study*

1999 • 95 citations

Capillary growth: a two-cell system.

1992 • 85 citations

Retention of PDGFR-β function in mice in the absence of phosphatidylinositol 3′-kinase and phospholipase Cγ signaling pathways

2000 • 76 citations

Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice

2001 • 75 citations

A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells

2001 • 60 citations

Angiogenesis in wound healing and tumor metastasis.

1993 • 56 citations

Analysis of relationships between pericytes and gas exchange capillaries in neonatal and mature bovine lungs

1983 • 48 citations

Morphogenesis of the Branchial Vascular Sector

2002 • 44 citations

Neuron-Specific Ablation of PDGF-B Is Compatible with Normal Central Nervous System Development and Astroglial Response to Injury

2003 • 39 citations

cGMP-dependent protein kinase is present in high concentrations in contractile cells of the kidney vasculature.

1986 • 38 citations

PDGF-induced coupling of function with metabolism in microvascular pericytes of the retina.

2001 • 22 citations

[Ultrastructural differences between the choriocapillaries and retinal capillaries on the human eye].

1969 • 7 citations