DNA binding by the Myc oncoproteins

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1985 • 1,782 citations

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

1982 • 1,746 citations

Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc

1991 • 1,650 citations

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

1982 • 1,424 citations

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

1983 • 1,407 citations

Facilitated Target Location in Biological Systems

1989 • 1,011 citations

Sequence-Specific DNA Binding by the c-Myc Protein

1990 • 893 citations

Transposition and amplification of oncogene-related sequences in human neuroblastomas

1983 • 711 citations

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

1985 • 652 citations

Methylation-Sensitive Sequence-Specific DNA Binding by the c-Myc Basic Region

1991 • 596 citations

The MYC protein activates transcription of the alpha-prothymosin gene.

1991 • 589 citations

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

1990 • 584 citations

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

1991 • 576 citations

New light on Myc and Myb. Part II. Myb.

1990 • 487 citations

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

1990 • 484 citations

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

1988 • 481 citations

Myc and Max proteins possess distinct transcriptional activities

1992 • 478 citations

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max

1992 • 458 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

Myc and Max associate in vivo.

1992 • 428 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

Dominant negative MYC blocks transformation by ABL oncogenes

1992 • 410 citations

Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy

1990 • 340 citations

Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.

1990 • 330 citations

New light on Myc and Myb. Part I. Myc.

1990 • 325 citations

Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains.

1990 • 316 citations

Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation.

1988 • 314 citations

Identification of the Human c-myc Protein Nuclear Translocation Signal

1988 • 299 citations

Fos-Jun heterodimers and jun homodimers bend DNA in opposite orientations: Implications for transcription factor cooperativity

1991 • 296 citations

Myc oncoproteins are phosphorylated by casein kinase II.

1989 • 287 citations

Max: functional domains and interaction with c-Myc.

1992 • 280 citations

SPXX, a frequent sequence motif in gene regulatory proteins

1989 • 276 citations

myc Family Oncogenes in the Development of Normal and Neoplastic Cells

1991 • 245 citations

SPKK, a new nucleic acid-binding unit of protein found in histone.

1989 • 237 citations

A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression.

1991 • 231 citations

Casein kinase II inhibits the DNA-binding activity of Max homodimers but not Myc/Max heterodimers.

1992 • 230 citations

Identification of the human c-myc protein nuclear translocation signal.

1988 • 207 citations

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein

1989 • 198 citations

Determination of the c-MYC DNA-binding site.

1991 • 181 citations

Discrimination between related DNA sites by a single amino acid residue of Myc-related basic-helix-loop-helix proteins.

1992 • 171 citations

Molecular Characterization of Helix-Loop-Helix Peptides

1992 • 166 citations

Function of the c‐Myc oncoprotein

1992 • 163 citations

Intracellular leucine zipper interactions suggest c-Myc hetero-oligomerization.

1991 • 161 citations

The RNA of avian acute leukemia virus MC29.

1977 • 154 citations

Synthetic DNA bending sequences increase the rate of in vitro transcription initiation at the Escherichia coli lac promoter

1991 • 148 citations

The N-Myc oncoprotein is associated in vivo with the phosphoprotein Max(p20/22) in human neuroblastoma cells.

1991 • 148 citations

The leucine zipper of TFE3 dictates helix-loop-helix dimerization specificity.

1991 • 129 citations

Augmented expression of normal c-myc is sufficient for cotransformation of rat embryo cells with a mutant ras gene.

1985 • 117 citations

Catabolite activator protein-induced DNA bending in transcription initiation

1991 • 88 citations

Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity.

1987 • 78 citations

Initiation of transcription by RNA polymerase II

1989 • 68 citations

Myc meets its max

1991 • 66 citations

Transgenic rabbits with lymphocytic leukemia induced by the c-myc oncogene fused with the immunoglobulin heavy chain enhancer.

1988 • 65 citations

DNA binding activities of c-Myc purified from eukaryotic cells.

1992 • 57 citations

Opposite orientations of DNA bending by c-Myc and Max.

1992 • 53 citations

Are myc proteins transcription factors?

1990 • 45 citations

DNA-binding domain of human c-Myc produced in Escherichia coli.

1989 • 40 citations

First non-vertebrate member of the myc gene family is seasonally expressed in an invertebrate testis.

1992 • 32 citations

Deleted Work

1955 • 0 citations