Intracellular leucine zipper interactions suggest c-Myc hetero-oligomerization.

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

The packing of α-helices: simple coiled-coils

1953 • 1,549 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

Molecular cloning (2nd Ed)

1989 • 1,191 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1988 • 1,006 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Evidence That the Leucine Zipper Is a Coiled Coil

1989 • 869 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.

1988 • 830 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

Leucine Repeats and an Adjacent DNA Binding Domain Mediate the Formation of Functional cFos-cJun Heterodimers

1989 • 676 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

Parallel Association of Fos and Jun Leucine Zippers Juxtaposes DNA Binding Domains

1989 • 607 citations

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

1990 • 584 citations

Activators and targets

1990 • 582 citations

Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro.

1988 • 511 citations

Characterization of junD: a new member of the jun proto-oncogene family.

1989 • 492 citations

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

1990 • 484 citations

Preferential Heterodimer Formation by Isolated Leucine Zippers from Fos and Jun

1989 • 469 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

1988 • 455 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.

1987 • 395 citations

A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein

1990 • 391 citations

Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins

1989 • 358 citations

Transcriptional regulation by dimerization: Two sides to an incestuous relationship

1990 • 343 citations

Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.

1990 • 330 citations

The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.

1989 • 318 citations

Identification of the Human c-myc Protein Nuclear Translocation Signal

1988 • 299 citations

Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.

1988 • 289 citations

Tropomyosin: Crystal structure, polymorphism and molecular interactions

1969 • 281 citations

The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous

1987 • 260 citations

A helix-loop-helix protein related to the immunoglobulin E box-binding proteins.

1990 • 244 citations

Cognate DNA Binding Specificity Retained After Leucine Zipper Exchange Between GCN4 and C/EBP

1989 • 237 citations

Biochemical analysis of transcriptional activation by Jun: Differential activity of c- and v-Jun

1989 • 225 citations

DNA-bound Fos proteins activate transcription in yeast

1988 • 223 citations

Trans splicing involves a novel form of small nuclear ribonucleoprotein particles

1988 • 210 citations

Identification of the human c-myc protein nuclear translocation signal.

1988 • 207 citations

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein

1989 • 198 citations

Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins.

1989 • 164 citations

An Amino-Terminal c-Myc Domain Required for Neoplastic Transformation Activates Transcription

1990 • 153 citations

Oncogenes and the molecular origins of cancer

1991 • 142 citations

Eukaryotic Transcriptional Regulatory Proteins

1989 • 93 citations

Fos and jun cooperate in transcriptional regulation via heterologous activation domains.

1990 • 82 citations

Structure of α-Keratin

1959 • 78 citations

A Helix-Loop-Helix Protein Related to the Immunoglobulin E Box-Binding Proteins

1990 • 78 citations

Analysis of dimerization and DNA binding functions in Fos and Jun by domain-swapping: involvement of residues outside the leucine zipper/basic region.

1990 • 67 citations

The myc Oncogene: Its Role in Transformation and Differentiation

1986 • 64 citations

Transcription factor interactions: selectors of positive or negative regulation from a single DNA element

1990 • 55 citations

Effect of Temperature on, and Reproducibility of, the Charge Transfer to Solvent Spectrum of Aqueous Iodide

1971 • 29 citations

Fos and Jun Cooperate in Transcriptional Regulation via Heterologous Activation Domains

1990 • 21 citations

Characterization and Nuclear Localization of the v- and c-myc Proteins

1986 • 9 citations

7 Nuclear Oncogenes

1989 • 4 citations