Transgenic rabbits with lymphocytic leukemia induced by the c-myc oncogene fused with the immunoglobulin heavy chain enhancer.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1985 • 1,782 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1985 • 1,292 citations

Production of transgenic rabbits, sheep and pigs by microinjection

1985 • 1,063 citations

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1984 • 906 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity

1983 • 702 citations

Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2.

1984 • 529 citations

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

1986 • 441 citations

Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.

1983 • 436 citations

Erythroid-specific expression of human beta-globin genes in transgenic mice.

1985 • 436 citations

Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development

1986 • 427 citations

Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas.

1983 • 330 citations

Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice.

1985 • 242 citations

Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice

1984 • 239 citations

Specific expression of a foreign β-globin gene in erythroid cells of transgenic mice

1985 • 235 citations

Oncogenesis of the Lens in Transgenic Mice

1987 • 202 citations

Molecular cloning of the avian myelocytomatosis virus genome and recovery of infectious virus by transfection of chicken cells

1981 • 181 citations

Developmental regulation of alpha-fetoprotein genes in transgenic mice.

1985 • 154 citations

High expression of cloned immunoglobulin k gene in transgenic mice is restricted to B lymphocytes

1984 • 114 citations

Elastase I Promoter Directs Expression of Human Growth Hormone and SV40 T Antigen Genes to Pancreatic Acinar Cells in Transgenic Mice

1985 • 110 citations

Tissue-specific expression of rat myosin light-chain 2 gene in transgenic mice

1985 • 105 citations

Organization and polymorphism of rabbit immunoglobulin heavy chain genes.

1985 • 77 citations

Immunoglobulin synthesis by neoplastic B lymphocytes: free light chain synthesis as a marker of B cell differentiation.

1980 • 69 citations

The role of rabbit Ia molecules in immune functions as determined with the use of an anti-Ia monoclonal antibody.

1984 • 56 citations

Structural analysis of a rabbit immunoglobulinx2 J-C locus reveals multiple deletions

1983 • 52 citations

Developmental Regulation of α-Fetoprotein Genes in Transgenic Mice

1985 • 49 citations

Lymphosarcoma in the Rabbit: Genetics and Pathology<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1970 • 27 citations

Transformation by Simian Virus 40 of Spleen Cells from a Hyperimmune Rabbit: Evidence for Synthesis of Immunoglobulin by the Transformed Cells

1974 • 26 citations

Lymphosarcoma with lymphoblastic leukemia in a New Zealand white rabbit.

1978 • 19 citations

Lymphoblastic leukaemia in a rabbit: a case report

1980 • 18 citations