von Willebrand factor in factor VIII concentrates protects against neutralization by factor VIII antibodies of haemophilia A patients

The Life Cycle of Coagulation Factor VIII in View of Its Structure and Function

1998 • 421 citations

The Inhibitor Antibody Response Is More Complex in Hemophilia A Patients Than in Most Nonhemophiliacs With Factor VIII Autoantibodies

1997 • 180 citations

A human antibody directed to the factor VIII C1 domain inhibits factor VIII cofactor activity and binding to von Willebrand factor

2000 • 125 citations

The Half-life of Infused Factor VIII Is Shorter in Hemophiliac Patients with Blood Group 0 than in those with Blood Group A

2000 • 115 citations

Inter‐individual variation in half‐life of infused recombinant factor VIII is related to pre‐infusion von Willebrand factor antigen levels

1995 • 104 citations

Factor VIII Inhibitor Antibodies with C2 Domain Specificity Are Less inhibitory to Factor VIII Complexed with von Willebrand Factor

1996 • 96 citations

Common inhibitory effects of human anti‐C2 domain inhibitor alloantibodies on factor VIII binding to von Willebrand factor

1995 • 69 citations

Variation in factor VIII inhibitor reactivity with different commercial factor VIII preparations

1996 • 63 citations

Immunoblot analysis shows changes in factor VIII inhibitor chain specificity in factor VIII inhibitor patients over time

1988 • 47 citations

Epitope specificity and functional characterization of factor VIII inhibitors

1995 • 24 citations

Structure and function of Factor VIII

1995 • 20 citations

Variable inactivation of human factor VIII from different sources by human factor VIII inhibitors

2008 • 15 citations

Effect of von Willebrand Factor and Its Proteolytic Fragments on Kinetics of Interaction between the Light and Heavy Chains of Human Factor VIII

1999 • 14 citations