c-erbB-2 expression in benign and malignant breast disease

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene

1985 • 1,804 citations

The neu oncogene encodes an epidermal growth factor receptor-related protein

1986 • 1,131 citations

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185

1986 • 1,020 citations

erb B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 Cells

1987 • 1,015 citations

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms.

1987 • 619 citations

Sevenless , a Cell-Specific Homeotic Gene of Drosophila , Encodes a Putative Transmembrane Receptor with a Tyrosine Kinase Domain

1987 • 421 citations

OVEREXPRESSION OF THE c-erbB-2 ONCOPROTEIN IN HUMAN BREAST CARCINOMAS: IMMUNOHISTOLOGICAL ASSESSMENT CORRELATES WITH GENE AMPLIFICATION

1987 • 409 citations

Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis.

1987 • 360 citations

Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene.

1987 • 335 citations

Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila

1987 • 279 citations

Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas

1982 • 251 citations

Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen.

1986 • 231 citations

Association of multiple copies of the c-erbB-2 oncogene with spread of breast cancer.

1987 • 214 citations

Expression of the c‐erbB‐2 protein in normal and transformed cells

1987 • 197 citations

Cellular localisation of human epidermal growth factor receptor

1984 • 173 citations

Monoclonal antibodies identify a cell-surface antigen associated with an activated cellular oncogene

1984 • 158 citations

In situ intraduct carcinoma of the breast: A long term follow-up study

1975 • 98 citations

Amplification of the neu (c-erbB-2) Oncogene in Human Mammmary Tumors is Relatively Frequent and is Often Accompanied by Amplification of the Linked c-erbA Oncogene

1987 • 74 citations

Immunohistochemical localization of c-erbB-2 in human breast carcinomas

1987 • 74 citations