Sevenless , a Cell-Specific Homeotic Gene of Drosophila , Encodes a Putative Transmembrane Receptor with a Tyrosine Kinase Domain

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

The embryonic cell lineage of the nematode Caenorhabditis elegans

1983 • 4,070 citations

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Transposition of Cloned P Elements into Drosophila Germ Line Chromosomes

1982 • 1,560 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

Development of the Drosophila retina, a neurocrystalline lattice

1976 • 1,028 citations

Nucleotide sequence of rous sarcoma virus

1983 • 901 citations

Pattern Regulation in Epimorphic Fields

1976 • 871 citations

Lambdoid phages that simplify the recovery of in vitro recombinants

1977 • 779 citations

Immunological method for mapping genes on Drosophila polytene chromosomes.

1982 • 772 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7-deazaguanosine triphosphate in place of dGTP

1986 • 717 citations

Chapter 6 Positional Information and Pattern Formation

1971 • 663 citations

The lin-12 locus specifies cell fates in caenorhabditis elegans

1983 • 598 citations

CSF‐1—A mononuclear phagocyte lineage‐specific hemopoietic growth factor

1983 • 536 citations

Neuronal differentiation in the Drosophila ommatidium

1987 • 532 citations

Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro

1978 • 448 citations

HOMEOTIC GENES AND THE HOMEOBOX

1986 • 442 citations

Genetic dissection of the photoreceptor system in the compound eye of Drosophila melanogaster

1976 • 395 citations

An improved in situ hybridization method for the detection of cellular RNAs in Drosophila tissue sections and its application for localizing transcripts of the homeotic Antennapedia gene complex

1983 • 381 citations

Cell Recognition During Neuronal Development

1984 • 381 citations

lin-12, a nematode homeotic gene, is homologous to a set of mammalian proteins that includes epidermal growth factor

1985 • 369 citations

Decapentaplegic: A gene complex affecting morphogenesis in Drosophila melanogaster

1982 • 345 citations

Direct evidence that oncogenic tyrosine kinases and cyclic AMP-dependent protein kinase have homologous ATP-binding sites

1984 • 345 citations

Microdissection and cloning of DNA from a specific region of Drosophila melanogaster polytene chromosomes

1981 • 341 citations

Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.

1982 • 287 citations

A transposable P vector that confers selectable G418 resistance to Drosophila larvae

1985 • 286 citations

Chromosomal Deficiencies and the Embryonic Development of Drosophila Melanogaster

1937 • 235 citations

Asymmetry and directionality in production of new cell types during clonal growth: the switching pattern of homothallic yeast

1979 • 206 citations

The Drosophila EGF receptor gene homolog: Conservation of both hormone binding and kinase domains

1985 • 202 citations

The nucleotide sequence and the tissue-specific expression of Drosophila c-src

1985 • 201 citations

Sevenless : A Cell-Specific Homeotic Mutation of the Drosophila Eye

1986 • 197 citations

Affinity labeling of cAMP-dependent protein kinase with p-fluorosulfonylbenzoyl adenosine. Covalent modification of lysine 71.

1981 • 191 citations

Genetics of the nervous system inDrosophila

1982 • 178 citations

Cell lineage in the developing retina of Drosophila

1979 • 169 citations

The cellular dynamics of pattern formation in the eye of Drosophila

1985 • 166 citations

Molecular characterization and expression of sevenless, a gene involved in neuronal pattern formation in the Drosophila eye

1987 • 161 citations

Spatial Programming of Gene Expression in Early Drosophila Embryogenesis

1986 • 157 citations

THE GENETIC CONTROL OF CELL LINEAGE DURING NEMATODE DEVELOPMENT

1984 • 130 citations

Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody.

1986 • 123 citations

SHORTVEIN, A NEW COMPONENT OF THE DECAPENTAPLEGIC GENE COMPLEX IN DROSOPHILA MELANOGASTER

1985 • 114 citations

Compound eye of dipterans: Anatomical basis for integration — An electron microscope study

1966 • 107 citations

Alternative 5′ exons and tissue-specific expression of the Drosophila EGF receptor homolog transcripts

1986 • 106 citations

Proto-oncogene c-ros codes for a molecule with structural features common to those of growth factor receptors and displays tissue specific and developmentally regulated expression.

1986 • 100 citations

cell clones and pattern formation: Studies onsevenless, a mutant ofDrosophila melanogaster

1979 • 77 citations

Fine cytogenetical analysis of the band 10A1-2 and the adjoining regions in the Drosophila melanogaster X chromosome

1981 • 51 citations

Fine cytogenetical analysis of the band 10a1-2 and the adjoining regions in the Drosophila melanogaster X chromosome

1981 • 29 citations

Master Regulatory Loci in Yeast and Lambda

1985 • 27 citations

Introductory Comments

1985 • 9 citations