Nuclear trafficking of FGFR1: A role for the transmembrane domain

Analysis of membrane and surface protein sequences with the hydrophobic moment plot

1984 • 2,234 citations

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

1995 • 1,601 citations

Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia

1994 • 1,273 citations

The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol

1996 • 1,083 citations

Nuclear localization of EGF receptor and its potential new role as a transcription factor

2001 • 1,049 citations

γ-Secretase Cleavage and Nuclear Localization of ErbB-4 Receptor Tyrosine Kinase

2001 • 848 citations

Signal Sequence Recognition and Protein Targeting to the Endoplasmic Reticulum Membrane

1994 • 821 citations

A protein-conducting channel in the endoplasmic reticulum

1991 • 613 citations

Structural Basis for FGF Receptor Dimerization and Activation

1999 • 597 citations

Nuclear matrix: isolation and characterization of a framework structure from rat liver nuclei

1977 • 596 citations

FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern.

1991 • 541 citations

Fibroblast Growth Factors as Multifunctional Signaling Factors

1998 • 489 citations

Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3.

1991 • 415 citations

Nuclear and cytoplasmic localization of different basic fibroblast growth factor species

1990 • 332 citations

Protein Translocation: Tunnel Vision

1998 • 312 citations

A comprehensive analysis of the distribution of FGF-2 and FGFR1 in the rat brain

1995 • 260 citations

Fibroblast Growth Factor Receptors from Liver Vary in Three Structural Domains

1991 • 227 citations

Importin β–Mediated Nuclear Import of Fibroblast Growth Factor Receptor

2001 • 226 citations

Nuclear Translocation of fibroblast growth factor (FGF) receptors in response to FGF-2.

1996 • 222 citations

Pre-mRNA splicing and the nuclear matrix.

1987 • 220 citations

Biochemistry, 2nd edition

1983 • 218 citations

Novel Aspects of Degradation of T Cell Receptor Subunits from the Endoplasmic Reticulum (ER) in T Cells: Importance of Oligosaccharide Processing, Ubiquitination, and Proteasome-dependent Removal from ER Membranes

1998 • 218 citations

Multiple Forms of bFGF: Differential Nuclear and Cell Surface Localization

1991 • 210 citations

Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein

1998 • 206 citations

Proteins: Structures and Molecular Properties

1985 • 198 citations

Nuclear Cytoplasmic Shuttling by Thyroid Hormone Receptors

2001 • 149 citations

Surfing the Sec61 channel: bidirectional protein translocation across the ER membrane

1999 • 147 citations

Nuclear accumulation of FGF-2 is associated with proliferation of human astrocytes and glioma cells

1997 • 146 citations

Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells.

1994 • 133 citations

Nuclear accumulation of fibroblast growth factor receptors in human glial cells-association with cell proliferation

1997 • 125 citations

Nuclear accumulation of fibroblast growth factor receptors is regulated by multiple signals in adrenal medullary cells.

1996 • 114 citations

cAMP‐induced differentiation of human neuronal progenitor cells is mediated by nuclear fibroblast growth factor receptor‐1 (FGFR1)

2003 • 107 citations

Growth factor regulation of cell growth and proliferation in the nervous system

1997 • 98 citations

Novel Nuclear Signaling Pathway Mediates Activation of Fibroblast Growth Factor-2 Gene by Type 1 and Type 2 Angiotensin II Receptors

2001 • 96 citations

Signal sequence recognition and protein targeting

1999 • 95 citations

Integrative nuclear FGFR1 signaling (INFS) pathway mediates activation of the tyrosine hydroxylase gene by angiotensin II, depolarization and protein kinase C

2002 • 93 citations

Involvement of Heat Shock Protein 90 in the Degradation of Mutant Insulin Receptors by the Proteasome

1998 • 92 citations

High affinity immunoreactive FGF receptors in the extracellular matrix of vascular endothelial cells--implications for the modulation of FGF-2.

1995 • 89 citations

Nuclear localization of functional FGF receptor 1 in human astrocytes suggests a novel mechanism for growth factor action

1996 • 84 citations

Translocation of TCRα Chains into the Lumen of the Endoplasmic Reticulum and Their Degradation

1993 • 75 citations

Pre-mRNA Splicing and the Nuclear Matrix

1987 • 75 citations

Fibroblast Growth Factor (FGF) Soluble Receptor 1 Acts as a Natural Inhibitor of FGF2 Neurotrophic Activity during Retinal Degeneration

1998 • 58 citations

Quantitative measurements of released amines from individual exocytosis events

1997 • 56 citations

Promoter regions involved in density-dependent regulation of basic fibroblast growth factor gene expression in human astrocytic cells.

1996 • 51 citations

Bone morphogenetic protein‐7 stimulates initial dendritic growth in sympathetic neurons through an intracellular fibroblast growth factor signaling pathway

2001 • 50 citations

Localization and regulation of basic fibroblast growth factor (FGF-2) and FGF receptor-1 in rat superior cervical ganglion after axotomy

1999 • 33 citations

Prediction of Protein Helices with a Derivative of the Strip-of-Helix Hydrophobicity Algorithm

1989 • 22 citations

New joint prediction algorithm (Q7-JASEP) improves the prediction of protein secondary structure

1991 • 19 citations