The age and evolution of non-LTR retrotransposable elements

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1997 • 38,984 citations

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

1997 • 2,256 citations

A molecular timescale for vertebrate evolution

1998 • 1,945 citations

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

1992 • 1,887 citations

The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc

1996 • 1,857 citations

The evolutionary dynamics of repetitive DNA in eukaryotes

1994 • 1,584 citations

Origin and evolution of retroelements based upon their reverse transcriptase sequences.

1990 • 1,351 citations

Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition

1993 • 1,129 citations

Human L1 Retrotransposon Encodes a Conserved Endonuclease Required for Retrotransposition

1996 • 1,093 citations

NONVIRAL RETROPOSONS: GENES, PSEUDOGENES, AND TRANSPOSABLE ELEMENTS GENERATED BY THE REVERSE FLOW OF GENETIC INFORMATION

1986 • 1,032 citations

High Frequency Retrotransposition in Cultured Mammalian Cells

1996 • 989 citations

Molecular archaeology of the Escherichia coli genome

1998 • 937 citations

The origin of interspersed repeats in the human genome

1996 • 595 citations

Origins and Evolutionary Relationships of Retroviruses

1989 • 581 citations

Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons

1997 • 546 citations

Intron phylogeny: a new hypothesis

1991 • 361 citations

Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNA.

1996 • 338 citations

Intron phylogeny: a new hypothesis

1991 • 278 citations

An env-like protein encoded by a Drosophila retroelement: evidence that gypsy is an infectious retrovirus.

1994 • 265 citations

Horizontal transmission, vertical inactivation, and stochastic loss of mariner-like transposable elements.

1995 • 262 citations

SINEs and LINEs share common 3′ sequences: a review

1997 • 259 citations

"Five Easy Pieces"

1991 • 255 citations

Transposable elements controlling I-R hybrid dysgenesis in D. melanogaster are similar to mammalian LINEs

1986 • 239 citations

MODERN THOUGHTS ON AN ANCYENT MARINERE: Function, Evolution, Regulation

1997 • 224 citations

Similarity of reverse transcriptase-like sequences of viruses, transposable elements, and mitochondrial introns.

1988 • 194 citations

LATERAL TRANSFER IN NATURAL POPULATIONS OF EUKARYOTES

1993 • 171 citations

In vitro properties of the first ORF protein from mouse LINE-1 support its role in ribonucleoprotein particle formation during retrotransposition

1997 • 158 citations

Amino acid sequence motif of group I intron endonucleases is conserved in open reading frames of group II introns

1994 • 146 citations

Characterization of a Non-long Terminal Repeat Retrotransposon cDNA (L1Tc) from : Homology of the First ORF with the Ape Family of DNA Repair Enzymes

1995 • 139 citations

The site-specific ribosomal insertion element type II of Bombyx mori (R2Bm) contains the coding sequence for a reverse transcriptase-like enzyme.

1987 • 134 citations

Unusual horizontal transfer of a long interspersed nuclear element between distant vertebrate classes

1998 • 132 citations

A phylogenetic perspective on P transposable element evolution in Drosophila

1997 • 129 citations

Evolution of retroposons by acquisition or deletion of retrovirus-like genes.

1991 • 129 citations

The site-specific ribosomal DNA insertion element R1Bm belongs to a class of non-long-terminal-repeat retrotransposons.

1988 • 128 citations

Potential Retroviruses in Plants: Tat1 Is Related to a Group of Arabidopsis thaliana Ty3/gypsy Retrotransposons That Encode Envelope-Like Proteins

1998 • 128 citations

Relationships between transposable elements based upon the integrase-transposase domains: Is there a common ancestor?

1996 • 119 citations

Studies on p40, the leucine zipper motif-containing protein encoded by the first open reading frame of an active human LINE-1 transposable element.

1992 • 115 citations

The RTE class of non-LTR retrotransposons is widely distributed in animals and is the origin of many SINEs

1998 • 113 citations

The Drosophila mobile element jockey belongs to LINEs and contains coding sequences homologous to some retroviral proteins

1988 • 111 citations

Self‐splicing group I and group II introns encode homologous (putative) DNA endonucleases of a new family

1994 • 111 citations

Evidence for horizontal transmission of the mobile element jockey between distant Drosophila species.

1990 • 101 citations

Determining and dating recent rodent speciation events by using L1 (LINE-1) retrotransposons

1998 • 99 citations

Retrotransposon R1Bm endonuclease cleaves the target sequence

1998 • 97 citations

Vertical transmission of the retrotransposable elements R1 and R2 during the evolution of the Drosophila melanogaster species subgroup.

1995 • 91 citations

SLACS retrotransposon fromTrypanosoma brucei gambienseis similar to mammalian LINEs

1990 • 88 citations

Sequence relationship of retrotransposable elements R1 and R2 within and between divergent insect species.

1993 • 84 citations

So, what about the molecular clock hypothesis?

1993 • 84 citations

Retrohoming: cDNA-Mediated Mobility of Group II Introns Requires a Catalytic RNA

1996 • 81 citations

Multiple Mariner Transposons in Flatworms and Hydras Are Related to Those of Insects

1997 • 76 citations

An analysis of replacement and synonymous changes in the rodent L1 repeat family.

1986 • 71 citations

A rapidly rearranging retrotransposon within the miniexon gene locus of Crithidia fasciculata.

1990 • 70 citations

R4, a non-LTR retrotransponson specific to the large subunit rRNA genes of nematodes

1995 • 68 citations

Nonviral Retroposons: Genes, Pseudogenes, and Transposable Elements Generated by the Reverse Flow of Genetic Information

1986 • 66 citations

A retrotransposon of the non-long terminal repeat class from the human blood fluke Schistosoma mansoni. Similarities to the chicken-repeat-1- like elements of vertebrates

1997 • 59 citations

Evolution of sea urchin retroviral-like (SURL) elements: evidence from 40 echinoid species

1999 • 57 citations

A LINE-like transposable element in Drosophila, the I factor, encodes a protein with properties similar to those of retroviral nucleocapsids

1997 • 57 citations

Analysis of the 5′ Junctions of R2 Insertions With the 28S Gene: Implications for Non-LTR Retrotransposition

1996 • 57 citations

Tadl-1, an active LINE-like element of Neurospora crassa

1994 • 55 citations

Evidence that Chicken CR1 Elements Represent a Novel Family of Retroposons

1989 • 52 citations

Evolutionary dynamics of Ty1-copia group retrotransposons in grass shown by reverse transcriptase domain analysis

1999 • 51 citations

The Site-Specific Ribosomal DNA Insertion Element R1Bm Belongs to a Class of Non-Long-Terminal-Repeat Retrotransposons

1988 • 50 citations

Rte‐1, a retrotransposon‐like element in Caenorhabditis elegans

1996 • 48 citations

2.2 å resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains)

1994 • 46 citations

Evolutionary stability of the R1 retrotransposable element in the genus Drosophila.

1995 • 41 citations

A single lineage of r2 retrotransposable elements is an active, evolutionarily stable component of the Drosophila rDNA locus

1997 • 41 citations

R1 and R2 retrotransposable elements of Drosophila evolve at rates similar to those of nuclear genes.

1995 • 39 citations

L1 (LINE-1) retrotransposable elements provide a "fossil" record of the phylogenetic history of murid rodents.

1995 • 35 citations

Evidence that chicken CR1 elements represent a novel family of retroposons.

1989 • 35 citations

Evolutionary Relationships Among the Members of an Ancient Class of Non-LTR Retrotransposons Found in the Nematode Caenorhabditis elegans

1998 • 28 citations

Phylogeny, rates of evolution, and patterns of codon usage among sea urchin retroviral-like elements, with implications for the recognition of horizontal transfer.

1995 • 27 citations

Evolution of R1 and R2 in the rDNA units of the genus Drosophila

1997 • 27 citations

Structural, genomic, and phylogenetic analysis of Lian, a novel family of non-LTR retrotransposons in the yellow fever mosquito, Aedes aegypti

1998 • 25 citations

bilbo, a non-LTR retrotransposon of Drosophila subobscura: a clue to the evolution of LINE-like elements in Drosophila

1997 • 22 citations

A non-LTR retrotransposon from the Hawaiian Drosophila: the LOA element

1992 • 21 citations

Molecular Evolution of Two Lineages of L1 (LINE-1) Retrotransposons in the California Mouse, Peromyscus californicus

1998 • 19 citations

Relationships Between Transposable Elements Based Upon the Integrase-Transposase Domains: Is There a Common Ancestor?

1996 • 12 citations

Lateral Transfer in Natural Populations of Eukaryotes

1993 • 9 citations

Identification of a 5′ truncated non-LTR-retrotransposon, YAKPs1 from the variegated cutworm, Peridroma saucia, using PCR

1996 • 7 citations