2.2 å resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains)

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1992 • 3,863 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

1992 • 1,887 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Identification of four conserved motifs among the RNA-dependent polymerase encoding elements.

1989 • 1,195 citations

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.

1993 • 1,097 citations

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

1985 • 855 citations

Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A

1990 • 622 citations

Crystal structure at 1.7 Å of the bovine papillomavirus-1 E2 DMA-binding domain bound to its DNA target

1992 • 344 citations

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.

1994 • 329 citations

Histogram matching as a new density modification technique for phase refinement and extension of protein molecules

1990 • 163 citations

Crystal structure of the ribosomal protein S6 from Thermus thermophilus.

1994 • 147 citations

Crystal structure of the ribosomal protein S6 from Thermus thermophilus.

1994 • 137 citations

Review of HIV-1 reverse transcriptase three-dimensional structure: Implications for drug design

1993 • 131 citations

Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase

1993 • 118 citations

Knocking-Out Concentrations of HIV-1-Specific Inhibitors Completely Suppress HIV-1 Infection and Prevent the Emergence of Drug-Resistant Virus

1993 • 67 citations

Bent crystal, bent multilayer optics on a multipole wiggler line for an x-ray diffractometer with an imaging plate detector

1992 • 60 citations