Folding/unfolding kinetics of mutant forms of iso-1-cytochrome c with replacement of proline-71

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues

1975 • 1,108 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

Computer simulation of protein folding

1975 • 1,020 citations

Conformational preferences of amino acids in globular proteins

1978 • 653 citations

Conformation change of cytochrome c

1981 • 559 citations

Algorithms for prediction of α-helical and β-structural regions in globular proteins

1974 • 465 citations

How good are predictions of protein secondary structure?

1983 • 375 citations

Simple alkanethiol groups for temporary blocking of sulfhydryl groups of enzymes

1975 • 311 citations

The Structure and History of an Ancient Protein

1972 • 201 citations

GENETIC ANALYSIS OF STAPHYLOCOCCAL NUCLEASE: IDENTIFICATION OF THREE INTRAGENIC "GLOBAL" SUPPRESSORS OF NUCLEASE-MINUS MUTATIONS

1985 • 189 citations

Evidence for the Existence of Two Functionally Distinct Forms of Cytochrome c Monomer at Alkaline pH

1965 • 167 citations

A quantitative treatment of the kinetics of the folding transition of ribonuclease A

1976 • 167 citations

Site-directed mutagenesis of cytochrome c shows that an invariant Phe is not essential for function

1985 • 151 citations

Thermodynamic stability and point mutations of bacteriophage T4 lysozyme

1984 • 149 citations

Kinetics of unfolding and refolding of proteins

1973 • 145 citations

Amino acid replacements in yeast iso-1-cytochrome c. Comparison with the phylogenetic series and the tertiary structure of related cytochromes c.

1986 • 125 citations

Urea-induced unfolding of the .alpha. subunit of tryptophan synthase: evidence for a multistate process

1981 • 109 citations

Prediction of protein structure from amino acid sequence

1978 • 103 citations

Effects of the phenylalanine-22 .fwdarw. leucine, glutamic acid-49 .fwdarw. methionine, glycine-234 .fwdarw. aspartic acid and glycine-234 .fwdarw. lysine mutations on the folding and stability of the .alpha. subunit of tryptophan synthase from Escherichia coli

1986 • 99 citations

Nature of the fast and slow refolding reactions of iron(III) cytochrome c

1981 • 65 citations

Guanidine hydrochloride induced unfolding of yeast iso-2 cytochrome c

1981 • 62 citations

Effect of a single amino acid substitution on the folding of the .alpha. subunit of tryptophan synthase

1983 • 61 citations

Effect of single amino acid substitutions on the thermal stability of the .alpha. subunit of tryptophan synthase

1980 • 60 citations

Involvement of prolines-114 and -117 in the slow refolding phase of ribonuclease A as determined by isomer-specific proteolysis

1984 • 59 citations

Kinetic analysis of the reversible folding reactions of small proteins: Application to the folding of lysozyme and cytochrome c

1977 • 56 citations

Characterization of the slow steps in the folding of the .alpha. subunit of tryptophan synthase

1981 • 54 citations

Characterization of an early intermediate in the folding of the .alpha. subunit of tryptophan synthase by hydrogen exchange measurement

1985 • 47 citations

Folding of yeast iso-1-AM cytochrome c

1983 • 47 citations

Substitutions of proline 76 in yeast iso-1-cytochrome c. Analysis of residues compatible and incompatible with folding requirements.

1985 • 37 citations

Effect of single amino acid substitutions at the same position on stability of a two-domain protein

1982 • 37 citations

Structural intermediates in folding of yeast iso-2 cytochrome c

1983 • 33 citations

Proline isomerization during refolding of ribonuclease A is accelerated by the presence of folding intermediates

1986 • 32 citations

Calorimetric study of tryptophan synthase α-subunit and two mutant proteins

1982 • 29 citations

Kinetics of the reduction of horse heart ferricytochrome c. Ascorbate reduction in the presence and absence of urea.

1980 • 27 citations

Slow refolding kinetics in yeast iso-2 cytochrome c

1985 • 23 citations

Kinetics of unfolding and folding of horse heart ferricytochrome c with urea.

1981 • 16 citations

A study on the role of evolutionarily invariant leucine 32 of cytochrome c.

1986 • 15 citations

Thermal denaturation of tryptophan synthase alpha-subunit. Comparison of the values of thermodynamic parameters of unfolding obtained from van't Hoff analysis of CD measurement with those from calorimetry.

1984 • 14 citations