Effect of single amino acid substitutions at the same position on stability of a two-domain protein

The Stability of Globular Protein

1975 • 648 citations

Transfer RNA: Biological Aspects

1981 • 274 citations

Effect of a single amino acid substitution on stability of conformation of a protein

1977 • 127 citations

[46] Chorismate to tryptophan (Escherichia coli)—anthranilate synthetase, PR transferase, PRA isomerase, InGP synthetase, tryptophan synthetase

1970 • 119 citations

An active proteolytic derivative of the .alpha. subunit of tryptophan synthase. Identification of the site of cleavage and characterization of the fragments

1979 • 112 citations

Biochemistry of Thermophily

1978 • 111 citations

Guanidine hydrochloride-induced unfolding of the .alpha. subunit of tryptophan synthase and of the two .alpha. proteolytic fragments: evidence for stepwise unfolding of the two .alpha. domains

1982 • 88 citations

Amino acid replacements of the glutamic acid residue at position 48 in the tryptophan synthetase a protein of Escherichia coli

1968 • 78 citations

Tryptophan Synthetase α Chain Positions Affected by Mutations near the Ends of the Genetic Map of trpA of Escherichia coli

1972 • 58 citations

Comparison of Denaturation by Guanidine Hydrochloride of the Wild Type Tryptophan Synthase α-Subunit of Escherichia coli and Two Mutant Proteins (Glu 49—Met or Gln)

1979 • 53 citations

pH dependence of stability of the wild-type tryptophan synthase α-subunit and two mutant proteins (Glu49 → Met or Gln)

1980 • 45 citations

Amino-Terminally Formylated Tryptophan Synthase α-Subunit Produced by the trp Operon Cloned in a Plasmid Vector

1980 • 32 citations

State of Tyr49 in a Mutant Tryptophan Synthase α-Subunit Substituted at Position 49

1980 • 27 citations