Proline isomerization during refolding of ribonuclease A is accelerated by the presence of folding intermediates

Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues

1975 • 1,108 citations

Acid catalysis of the formation of the slow-folding species of RNase A: Evidence that the reaction is proline isomerization

1978 • 229 citations

Role of proline isomerization in folding of ribonuclease A at low temperatures

1979 • 161 citations

Mechanism of folding of ribonuclease A. Slow refolding is a sequential reaction via structural intermediates

1983 • 158 citations

Both the Fast and Slow Refolding Reactions of Ribonuclease A Yield Native Enzyme

1973 • 157 citations

Effect of proline residues on protein folding

1981 • 155 citations

Test of the extended two-state model for the kinetic intermediates observed in the folding transition of ribonuclease A

1978 • 137 citations

Unfolding and refolding of the constant fragment of the immunoglobulin light chain

1982 • 124 citations

Kinetic study of protein unfolding and refolding using urea gradient electrophoresis

1980 • 121 citations

A Native‐Like Intermediate on the Ribonuclease A Folding Pathway

1981 • 118 citations

Isomerization of proline-93 during the unfolding and refolding of ribonuclease A

1983 • 73 citations

Nature of the fast and slow refolding reactions of iron(III) cytochrome c

1981 • 65 citations

Identification and characterization of the direct folding process of hen egg-white lysozyme

1982 • 65 citations

Possible implications of many proline residues for the kinetics of protein unfolding and refolding

1978 • 63 citations

Involvement of prolines-114 and -117 in the slow refolding phase of ribonuclease A as determined by isomer-specific proteolysis

1984 • 59 citations

The role of proline residues in the folding kinetics of the bovine pancreatic trypsin inhibitor derivative RCAM(14–38)

1981 • 48 citations

Mechanism for the unfolding and refolding of ribonuclease A. Simulations using a simple model with no structural intermediates

1983 • 43 citations

Fast- and slow-refolding forms of unfolded ribonuclease A differ in tyrosine fluorescence

1982 • 36 citations

Kinetics and mechanism of the refolding of denatured ribonuclease A

1985 • 34 citations

Protection of amide protons in folding intermediates of ribonuclease A measured by pH pulse exchange curves

1985 • 27 citations