Phagocytosis following Translocation of the Neutrophil b‐Cytochrome from the Specific Granule to the Plasma Membrane is Associated with an Increased Leakage of Reactive Oxygen Species

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

1983 • 1,808 citations

Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.

1983 • 938 citations

The O2−-forming NADPH oxidase of the phagocytes: nature, mechanisms of activation and function

1986 • 665 citations

H2O2 release from human granulocytes during phagocytosis. I. Documentation, quantitation, and some regulating factors.

1975 • 653 citations

H2O2 Release from Human Granulocytes during Phagocytosis

1977 • 586 citations

Laboratory Manual of Neutrophil Function

1986 • 443 citations

A quantitative fluorimetric assay for the determination of oxidant production by polymorphonuclear leukocytes: Its use in the simultaneous fluorimetric assay of cellular activation processes

1984 • 322 citations

The superoxide-forming enzymatic system of phagocytes

1988 • 315 citations

The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease.

1989 • 286 citations

NADPH oxidase of human neutrophils. Subcellular localization and characterization of an arachidonate-activatable superoxide-generating system.

1987 • 266 citations

Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils.

1986 • 246 citations

The Human Neutrophil Respiratory Burst Oxidase

1990 • 225 citations

Subcellular localization of the human neutrophil NADPH oxidase. b-Cytochrome and associated flavoprotein.

1984 • 187 citations

Identification of a highly mobilizable subset of human neutrophil intracellular vesicles that contains tetranectin and latent alkaline phosphatase.

1990 • 157 citations

Diffusion of extracellular hydrogen peroxide into intracellular compartments of human neutrophils. Studies utilizing the inactivation of myeloperoxidase by hydrogen peroxide and azide.

1985 • 152 citations

Ultrastructural localization of cytochrome b in the membranes of resting and phagocytosing human granulocytes.

1990 • 145 citations

Analytical Subcellular Fractionation of Human Granulocytes with Reference to the Localization of Vitamin B12-Binding Proteins

1975 • 140 citations

Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor

1992 • 134 citations

Differences in the ingestion mechanisms of IgG and C3b particles in phagocytosis by neutrophils.

1982 • 129 citations

Cytosolic components of the respiratory burst oxidase: resolution of four components, two of which are missing in complementing types of chronic granulomatous disease.

1989 • 123 citations

Difference in extracellular radical release after chemotactic factor and calcium ionophore activation of the oxygen radical-generating system in human neutrophils

1987 • 72 citations

Extracellular release of reactive oxygen species from human neutrophils upon interaction with Escherichia coli strains causing renal scarring

1991 • 66 citations

Dual granule localization of the dormant NADPH oxidase and cytochrome b₅₅₉ in human neutrophils

1989 • 65 citations

Neutrophil killing of two type 1 fimbria-bearing Escherichia coli strains: dependence on respiratory burst activation

1990 • 54 citations

Leukocyte-Induced Tissue Injury

1988 • 52 citations

Mixed Enzyme‐Linked Immunosorbent Assay (MELISA) for HLA Class I Antigen: a Plasma Membrane Marker

1990 • 45 citations

Mechanisms in Neutrophil Priming: Characterization of the Oxidative Response Induced by Formylmethionyl‐Leucyl‐Phenylalanine in Human Exudated Cells

1991 • 38 citations

Characteristics of the granulocyte chemiluminescence reaction following an interaction between human neutrophils and Salmonella typhimurium bacteria

1988 • 35 citations

Difference in hydrogen peroxide release between human neutrophils and neutrophil cytoplasts following calcium ionophore activation. A role of the subcellular granule in activation of the NADPH-oxidase in human neutrophils?

1989 • 33 citations

Intracellular production of reactive oxygen species in human neutrophils following activation by the soluble stimuli FMLP, dioctanoylglycerol and ionomycin

1991 • 27 citations

The Calcium Ionophore Ionomycin can Prime, but not Activate, the Reactive Oxygen Generating System in Differentiated HL-60 Cells

1989 • 26 citations

The Neutrophil: Function and Clinical Disorders

1980 • 13 citations

The effects of N‐ethylmaleimide on extracellularly and intracellularly generated chemiluminescence in neutrophils indicate that the rate of deactivation of NADPH‐oxidase is higher when the oxidase system is localized on the plasma membrane than when it is localized on the phagosomal membrane

1991 • 10 citations

Degranulation in human neutrophils primes the cells for subsequent responsiveness to the chemoattractant N-formylmethionylleucylphenylalanine but does not increase the sensitivity of the NADPH-oxidase to an intracellular calcium rise

1990 • 9 citations