The effects of N‐ethylmaleimide on extracellularly and intracellularly generated chemiluminescence in neutrophils indicate that the rate of deactivation of NADPH‐oxidase is higher when the oxidase system is localized on the plasma membrane than when it is localized on the phagosomal membrane

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

The importance of free radicals and catalytic metal ions in human diseases

1985 • 939 citations

The neutrophil: Function and clinical disorders

1978 • 670 citations

The O2−-forming NADPH oxidase of the phagocytes: nature, mechanisms of activation and function

1986 • 665 citations

The neutrophil: Function and clinical disorders

1979 • 628 citations

Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation.

1990 • 435 citations

Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages

1984 • 335 citations

The superoxide-forming enzymatic system of phagocytes

1988 • 315 citations

NADPH oxidase of human neutrophils. Subcellular localization and characterization of an arachidonate-activatable superoxide-generating system.

1987 • 266 citations

Chemoattractant-Regulated Mobilization of a Novel Intracellular Compartment in Human Neutrophils

1987 • 256 citations

Intra- and extracellular events in luminol-dependent chemiluminescence of polymorphonuclear leukocytes

1984 • 213 citations

EFFECT OF PHAGOCYTOSIS ON MEMBRANE TRANSPORT OF NONELECTROLYTES

1971 • 190 citations

Diffusion of extracellular hydrogen peroxide into intracellular compartments of human neutrophils. Studies utilizing the inactivation of myeloperoxidase by hydrogen peroxide and azide.

1985 • 152 citations

Luminol- and lucigenin-dependent chemiluminescence of neutrophils: role of degranulation.

1987 • 100 citations

The Inflammatory Reaction

1986 • 100 citations

Analysis of the bimodal chemiluminescence pattern stimulated in human neutrophils by chemotactic factors

1983 • 99 citations

Two distinct mechanisms for stimulation of oxygen-radical production by polymorphonuclear leucocytes

1983 • 98 citations

The inflammatory reaction

1985 • 96 citations

Rapid deactivation of NADPH oxidase in neutrophils: continuous replacement by newly activated enzyme sustains the respiratory burst

1988 • 75 citations

Difference in extracellular radical release after chemotactic factor and calcium ionophore activation of the oxygen radical-generating system in human neutrophils

1987 • 72 citations

The Respiratory Burst Oxidase

1988 • 65 citations

Leukocyte-Induced Tissue Injury

1988 • 52 citations

Activation of the neutrophil respiratory burst by chemoattractants: Regulation of the N-formyl peptide receptor in the plasma membrane

1988 • 43 citations

Analysis of horseradish peroxidase-amplified chemiluminescence produced by human neutrophils reveals a role for the superoxide anion in the light emitting reaction

1988 • 42 citations

Localization of the luminol‐dependent chemiluminescence reaction in human granulocytes

1989 • 38 citations

Threshold responses in production of reactive oxygen metabolites in individual neutrophils detected by flow cytometry and microfluorimetry

1987 • 37 citations

Characteristics of the granulocyte chemiluminescence reaction following an interaction between human neutrophils and Salmonella typhimurium bacteria

1988 • 35 citations

The effects of sulfhydryl inhibitors and cytochalasin on the cytoplasmic and cytoskeletal actin of human neutrophils

1987 • 28 citations

Selective enrichment of NADPH oxidase activity in phagosomes from guinea pig polymorphonuclear leukocytes

1982 • 28 citations

Effects of sulfhydryl reagents on phagocytosis and exocytosis in rabbit polymorphonuclear leukocytes

1980 • 25 citations

Metabolic requirements for maintenance of the chlortetracycline-labeled pool of membrane-bound calcium in human neutrophils

1983 • 13 citations

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