An AG→GG transition at a splice site in the myelin proteolipid protein gene in jimpy mice results in the removal of an exon

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Mutant Mice (Quaking and Jimpy) with Deficient Myelination in the Central Nervous System

1964 • 607 citations

Nucleotide sequences of two mRNAs for rat brain myelin proteolipid protein

1985 • 345 citations

Maturation of human white matter myelin. Fractionation of the myelin membrane proteins

1968 • 343 citations

Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice

1985 • 331 citations

Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin.

1987 • 300 citations

Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing.

1986 • 219 citations

Assignment of the Gene for Myelin Proteolipid Protein to the X Chromosome: Implications for X-Linked Myelin Disorders

1985 • 213 citations

Myelin deficient mice: Expression of myelin basic protein and generation of mice with varying levels of myelin

1987 • 194 citations

Individual exons encode the integral membrane domains of human myelin proteolipid protein.

1986 • 177 citations

Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse.

1987 • 174 citations

THE PROTEIN COMPOSITION OF ISOLATED MYELIN¹

1970 • 141 citations

Expression of Myelin Proteolipid Protein and Basic Protein in Normal and Dysmyelinating Mutant Mice

1986 • 93 citations

A neurological mutation (msd) of the mouse causing a deficiency of myelin synthesis

1970 • 87 citations

Characterization of Myelin Proteolipid mRNAs in Normal and Jimpy Mice

1986 • 80 citations

The gene encoding for the major brain proteolipid (PLP) maps on the q-22 band of the human X chromosome

1986 • 74 citations

Myelin proteolipid protein (PLP and DM-20) transcripts are deleted in jimpy mutant mice.

1986 • 71 citations

Characterization of myelin proteolipid mRNAs in normal and jimpy mice.

1986 • 69 citations

The genes for myelin

1987 • 29 citations