Molecular evolution of integrins: Genes encoding integrin β subunits from a coral and a sponge

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Crystal structure of the A domain from the a subunit of integrin CR3 (CD11 b/CD18)

1995 • 893 citations

Molecular Phylogeny of the Animal Kingdom

1988 • 743 citations

Amino acid sequence of the human fibronectin receptor.

1987 • 596 citations

Breaking the Integrin Hinge

1996 • 567 citations

Cloning of the $beta; subunit of the leukocyte adhesion proteins: Homology to an extracellular matrix receptor defines a novel supergene family

1987 • 520 citations

Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to “integrin”.

1987 • 466 citations

A β ₃ Integrin Mutation Abolishes Ligand Binding and Alters Divalent Cation-Dependent Conformation

1990 • 418 citations

Folding of the N-terminal, ligand-binding region of integrin α-subunits into a β-propeller domain

1997 • 414 citations

Integrin cytoplasmic interactions and bidirectional transmembrane signalling

1996 • 396 citations

Antibodies to the conserved cytoplasmic domain of the integrin beta 1 subunit react with proteins in vertebrates, invertebrates, and fungi.

1988 • 323 citations

Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin.

1995 • 308 citations

Targeted Mutations in Cell Adhesion Genes: What Have We Learned from Them?

1996 • 295 citations

Identification of amino acid sequences in the integrin beta 1 cytoplasmic domain implicated in cytoskeletal association

1992 • 285 citations

Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by Calcium

1995 • 281 citations

Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells.

1990 • 249 citations

The lethal myospheroid gene of Drosophila encodes a membrane protein homologous to vertebrate integrin beta subunits.

1988 • 235 citations

Integrin activation: the link between ligand binding and signal transduction

1996 • 227 citations

Origin of the Metazoa.

1990 • 216 citations

Characterization of beta pat-3 heterodimers, a family of essential integrin receptors in C. elegans.

1995 • 209 citations

Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.

1990 • 195 citations

Cell-surface regulation of β1-integrin activity on developing retinal neurons

1991 • 191 citations

Regulation of Integrin Affinity States through an NP XY Motif in the β Subunit Cytoplasmic Domain

1995 • 181 citations

Cloning and expression of a divergent integrin subunit beta 8.

1991 • 179 citations

Cloning, primary structure and properties of a novel human integrin beta subunit.

1990 • 170 citations

Ligand Binding to Integrin αIIbβ3 Is Dependent on a MIDAS-like Domain in the β3 Subunit

1996 • 168 citations

RGD-dependent linkage between plant cell wall and plasma membrane: consequences for growth.

1989 • 163 citations

The contribution of the extracellular matrix to gravisensing in characean cells

1992 • 150 citations

Mutation of a ligand binding domain of beta 3 integrin. Integral role of oxygenated residues in alpha IIb beta 3 (GPIIb-IIIa) receptor function.

1994 • 147 citations

A spontaneous mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa) helps define a ligand binding site.

1992 • 144 citations

Mutation of the Cytoplasmic Domain of the Integrin β3 Subunit

1995 • 144 citations

A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques.

1992 • 138 citations

Identification of putative ligand-binding sites of the integrin α4β1 (VLA-4, CD49d/CD29)

1995 • 128 citations

Complete amino acid sequence of an integrin beta subunit (beta 7) identified in leukocytes

1991 • 124 citations

On the origin of Metazoan adhesion receptors: cloning of integrin alpha subunit from the sponge Geodia cydonium

1997 • 122 citations

Enrichment of vitronectin‐ and fibronectin‐like proteins in NaCl‐adapted plant cells and evidence for their involvement in plasma membrane–cell wall adhesion

1993 • 122 citations

A molecular evolutionary framework for eukaryotic model organisms

1994 • 112 citations

Integrin and spectrin homologues, and cytoplasm-wall adhesion in tip growth

1995 • 104 citations

Integrins hold Drosophila together

1993 • 97 citations

A novel, tissue-specific integrin subunit, βν, expressed in the midgut of Drosophila melanogaster

1993 • 96 citations

The Role of Conserved Amino Acid Motifs within the Integrin β3 Cytoplasmic Domain in Triggering Focal Adhesion Kinase Phosphorylation

1997 • 91 citations

Short chain collagens in sponges are encoded by a family of closely related genes.

1991 • 86 citations

Critical Residues for Ligand Binding in an I Domain-like Structure of the Integrin β1 Subunit

1996 • 85 citations

β2 (CD18) Mutations Abolish Ligand Recognition by I Domain Integrins LFA-1 ( αLβ2, CD11a/CD18) and MAC-1 ( αMβ2, CD11b/CD18)

1995 • 83 citations

Inhibition of thigmostimulated cell differentiation with RGD-peptides inUromyces germlings

1996 • 82 citations

Fibronectin-like protein in Porifera: its role in cell aggregation.

1981 • 79 citations

Control of β1 Integrin Function

1996 • 79 citations

A genetic analysis of integrin function: Glanzmann thrombasthenia in vitro

1997 • 74 citations

Polar axis fixation in Fucus zygotes: components of the cytoskeleton and extracellular matrix

1991 • 66 citations

Covisualization by computation optical-sectioning microscopy of integrin and associated proteins at the cell membrane of living onion protoplasts

1996 • 57 citations

Structure/function analysis of the integrin beta 1 subunit by epitope mapping

1993 • 54 citations

Attachment of sponge cells to collagen substrata: Effect of a collagen assembly factor

1985 • 52 citations

Identification and cloning of an integrin β subunit from hemocytes of the freshwater crayfishPacifastacus leniusculus

1997 • 49 citations

Cloning and Characterization of Novel β Integrin Subunits from a Sea Urchin

1997 • 48 citations

Cell-extracellular matrix interactions under in vivo conditions during interstitial cell migration in Hydra vulgaris

1994 • 43 citations

Cloning and sequencing of a Porifera partial cDNA coding for a short‐chain collagen

1990 • 42 citations

A Novel Activating Anti-β1 Integrin Monoclonal Antibody Binds to the Cysteine-rich Repeats in the β1 Chain

1996 • 42 citations

A six‐armed, tenascin‐like protein extracted from the Porifera Oscarella tuberculata (Homosclerophorida)

1993 • 33 citations

The attachment of nematocytes from the primitive invertebrate Hydra to fibronectin is specific and RDG-dependent

1992 • 25 citations

A new alternative transcript encodes a 60 kDa truncated form of integrin β3

1994 • 21 citations

Evidence for Cell Surface Extracellular Matrix Binding Proteins inHydra vulgaris

1994 • 18 citations

A point mutation in the integrin beta 6 subunit abolishes both alpha v beta 6 binding to fibronectin and receptor localization to focal contacts.

1995 • 15 citations

Nucleotide sequence of ub52 from the cnidarian Acropora millepora reveals high evolutionary conservation

1996 • 8 citations