Redox Control of Neuronal Damage during Brain Ischemia after Middle Cerebral Artery Occlusion in the Rat: Immunohistochemical and Hybridization Studies of Thioredoxin

Reversible middle cerebral artery occlusion without craniectomy in rats.

1989 • 6,875 citations

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

THIOREDOXIN

1985 • 1,885 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Distinct effects of thioredoxin and antioxidants onthe activation of transcription factors NF-kappa B and AP-1.

1994 • 694 citations

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.

1991 • 591 citations

Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.

1994 • 571 citations

Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats.

1992 • 467 citations

Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats.

1990 • 266 citations

Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide

1994 • 252 citations

Changes in Amino Acid Neurotransmitters and Cerebral Blood Flow in the Ischemic Penumbral Region following Middle Cerebral Artery Occlusion in the Rat: Correlation with Histopathology

1993 • 220 citations

Free radical generation during brief period of cerebral ischemia may trigger delayed neuronal death

1990 • 216 citations

Nitric Oxide Donors Increase Blood Flow and Reduce Brain Damage in Focal Ischemia: Evidence That Nitric Oxide is Beneficial in the Early Stages of Cerebral Ischemia

1994 • 206 citations

Redox control of resistance to cis-diamminedichloroplatinum (II) (CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity.

1996 • 203 citations

Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor-dependent cytotoxicity on U937 cells.

1991 • 201 citations

Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemia

1993 • 181 citations

Protective effect of α-tocopherol on ischemic neuronal damage in the gerbil hippocampus

1990 • 180 citations

Reactive oxygen-reducing and protein-refolding activities of adult t cell leukemia-derived factor /human thioredoxin

1992 • 176 citations

N-Acetylcysteine-promoted Survival of PC12 Cells Is Glutathione-independent but Transcription-dependent

1995 • 174 citations

Regional Expression of Heat Shock Protein-70 mRNA and c-Fos mRNA following Focal Ischemia in Rat Brain

1992 • 171 citations

Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation

1992 • 166 citations

Global Cerebral Ischemia in the Rat: Online Monitoring of Oxygen Free Radical Production Using Chemiluminescence in vivo

1995 • 158 citations

Induction of c-Fos, junB, c-Jun, and hsp70 mRNA in Cortex, Thalamus, Basal Ganglia, and Hippocampus following Middle Cerebral Artery Occlusion

1994 • 150 citations

Expression and growth-promoting effect of adult t-cell leukemia-derived factor a human thioredoxin homologue in hepatocellular carcinoma

1992 • 145 citations

The predicted amino acid sequence of human thioredoxin is identical to that of the autocrine growth factor human adult T-cell derived factor (ADF): Thioredoxin mRNA is elevated in some human tumors

1994 • 141 citations

Human thioredoxin/adult T cell leukemia-derived factor activates the enhancer binding protein of human immunodeficiency virus type 1 by thiol redox control mechanism

1992 • 138 citations

Immunohistochemical Localization of Superoxide Dismutase in the Hippocampus following Ischemia in a Gerbil Model of Ischemic Tolerance

1995 • 129 citations

Neurotrophic factors: An evolutionary perspective

1994 • 121 citations

Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells

1995 • 115 citations

Thiol-mediated redox regulation of lymphocyte proliferation. Possible involvement of adult T cell leukemia-derived factor and glutathione in transferrin receptor expression.

1994 • 114 citations

Lipid peroxidation in focal cerebral ischemia

1989 • 100 citations

Neuroprotection by glial cells through adult T cell leukemia-derived factor/human thioredoxin (ADF/TRX)

1994 • 93 citations

IL-2 receptor(p55)/Tac-inducing factor. Purification and characterization of adult T cell leukemia-derived factor.

1988 • 90 citations

Thioredoxin increases the proliferation of human B-cell lines through a protein kinase C-dependent mechanism.

1994 • 77 citations

Distributions of Heat Shock Protein-70 mRNAs and Heat Shock Cognate Protein-70 mRNAs after Transient Global Ischemia in Gerbil Brain

1992 • 76 citations

The thioredoxin/thioredoxin reductase redox system and control of cell growth.

1994 • 76 citations

Localization of thioredoxin in the rat brain and functional implications

1995 • 74 citations

Ischemia Induces the Expression of the Platelet-Derived Growth Factor-B Chain in Neurons and Brain Macrophages in vivo

1994 • 73 citations

Expression of glial fibrillary acidic protein in areas of focal cerebral ischemia accompanies neuronal expression of 72-kDa heat shock protein

1995 • 70 citations

Tirilazad Mesylate Protects Vitamins C and E in Brain Ischemia‐Reperfusion Injury

1992 • 67 citations

Oxidative stress induces adult T cell leukemia derived factor/thioredoxin in the rat retina.

1994 • 67 citations

Astroglial expression of ATL-derived factor, a human thioredoxin homologue, in the gerbil brain after transient global ischemia

1993 • 64 citations

Acidosis-Induced Ischemic Brain Damage: Are Free Radicals Involved?

1991 • 55 citations

Reduction of activities of superoxide dismutase but not of glutathione peroxidase in rat brain regions following decapitation ischemia

1988 • 52 citations

An immunohistochemical study of copper/zinc superoxide dismutase and manganese superoxide dismutase following focal cerebral ischemia in the rat

1994 • 48 citations

Global elevation of brain superoxide dismutase activity following forebrain ischemia in rat

1991 • 44 citations

α-Tocopherol and ubiquinones in rat brain subjected to decapitation ischemia

1983 • 43 citations

SOD‐1 Transgenic Mice as a Model for Studies of Neuroprotection in Stroke and Brain Trauma^a

1994 • 40 citations

Thioredoxin from Activated Macrophages as a Trophic Factor for Central Cholinergic Neurons in Vitro

1993 • 36 citations

Expression of c-fos and inducible hsp-70 mRNA following a transient episode of focal ischemia that had non-lethal effects on the rat brain

1995 • 34 citations

Effects of α-tocopherol on lipid peroxidation and mitochondrial reduction of tetraphenyl tetrazolium in the rat brain

1994 • 20 citations

Adult T-cell leukaemia-derived factor/thioredoxin expression on the HTLV-I transformed T-cell lines: heterogeneous expression in ALT-2 cells.

1992 • 14 citations