Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats.

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

1986 • 2,584 citations

Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.

1978 • 2,254 citations

Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery Occlusion

1981 • 1,420 citations

Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats.

1986 • 1,257 citations

Central nervous systems trauma and strokeI. Biochemical considerations for oxygen radical formation and lipid peroxidation

1989 • 626 citations

Free radicals in cerebral ischemia.

1978 • 589 citations

A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction.

1986 • 588 citations

Central nervous system trauma and strokeII. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation

1989 • 580 citations

Free Radicals and Brain Damage

1993 • 527 citations

Focal Brain Ischemia in the Rat: Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries

1988 • 488 citations

Protection against oxygen toxicity by intravenous injection of liposome-entrapped catalase and superoxide dismutase.

1984 • 478 citations

Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury

1989 • 368 citations

Permeation of the erythrocyte stroma by superoxide radical

1978 • 367 citations

Appearance of superoxide anion radical in cerebral extracellular space during increased prostaglandin synthesis in cats.

1985 • 296 citations

Protective effects of liposome‐entrapped superoxide dismutase on posttraumatic brain edema

1987 • 283 citations

Transient Formation of Superoxide Radicals in Polyunsaturated Fatty Acid‐Induced Brain Swelling

1980 • 267 citations

Liposome-mediated augmentation of superoxide dismutase in endothelial cells prevents oxygen injury.

1983 • 230 citations

Glutathione and Ascorbate During Ischemia and Postischemic Reperfusion in Rat Brain

1980 • 218 citations

Protective effects of combined superoxide dismutase and deferoxamine on recovery of cerebral blood flow and function after cardiac arrest in dogs.

1987 • 141 citations

Chemiluminescence in hypoxic brain--the first report. Correlation between energy metabolism and free radical reaction.

1984 • 103 citations

Induction of Intracellular Superoxide Radical Formation by Arachidonic Acid and by Polyunsaturated Fatty Acids in Primary Astrocytic Cultures

1988 • 91 citations

Liposome-mediated augmentation of brain SOD and catalase inhibits CNS O2 toxicity

1984 • 85 citations

Ischemic cortical lesions after permanent occlusion of individual middle cerebral artery branches in rats.

1988 • 57 citations

Reduction of activities of superoxide dismutase but not of glutathione peroxidase in rat brain regions following decapitation ischemia

1988 • 52 citations

Hypoglycemic Brain Injury: Phospholipids, Free Fatty Acids, and Cyclic Nucleotides in the Cerebellum of the Rat after 30 and 60 Minutes of Severe Insulin-Induced Hypoglycemia

1981 • 38 citations

Initiation and propagation of lipid peroxidation in cerebral infarction models: Experimental studies

1986 • 26 citations

Application of spin-trapping study to rat ischemic brain homogenate incubated with NADPH and Fe-EDTA

1987 • 14 citations

Correlation among lipid peroxidation, brain energy metabolism and brain oedema in cerebral ischaemia

1988 • 9 citations

The Role of Oxygen Radicals in Brain Injury and Edema

2019 • 7 citations