Mechanisms Involved in Calcium‐Dependent Exocytosisa

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

1980 • 1,808 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

Constitutive and Regulated Secretion of Proteins

1987 • 1,021 citations

Protein Kinase C Contains a Pseudosubstrate Prototope in Its Regulatory Domain

1987 • 1,020 citations

Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.

1982 • 1,010 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.

1985 • 636 citations

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

1988 • 592 citations

Do GTPases direct membrane traffic in secretion?

1988 • 540 citations

Capacitance measurements reveal stepwise fusion events in degranulating mast cells

1984 • 506 citations

Calcium-dependence of catecholamine release from bovine adrenal medullary cells after exposure to intense electric fields

1982 • 500 citations

Involvement of GTP-binding “G” proteins in transport through the Golgi stack

1987 • 495 citations

rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.

1990 • 486 citations

Molecular Pharmacology of Botulinum Toxin and Tetanus Toxin

1986 • 469 citations

Aggregation of chromaffin granules by calpactin at micromolar levels of calcium

1988 • 443 citations

A simple method for the isolation of adrenal chromaffin granules on a large scale

1967 • 439 citations

Calcium and GTP: essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus.

1989 • 351 citations

A role for calpactin in calcium-dependent exocytosis in adrenal chromaffin cells

1989 • 321 citations

Calcium-dependent exocytosis in bovine adrenal medullary cells with leaky plasma membranes

1978 • 315 citations

Binding of myosin I to membrane lipids

1989 • 287 citations

Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes

1990 • 284 citations

Simultaneous electrical and optical measurements show that membrane fusion precedes secretory granule swelling during exocytosis of beige mouse mast cells.

1987 • 280 citations

Phospholipid-dependent Ca2+ binding by the 36-kDa tyrosine kinase substrate (calpactin) and its 33-kDa core.

1986 • 269 citations

The phorbol ester TPA increases the affinity of exocytosis for calcium in ‘leaky’ adrenal medullary cells

1983 • 269 citations

Exocytosis

1990 • 260 citations

Final steps in exocytosis observed in a cell with giant secretory granules.

1987 • 255 citations

Gelsolin: Calcium‐ and polyphosphoinositide‐regulated actin‐ modulating protein

1987 • 228 citations

Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP

1990 • 227 citations

MgATP-independent and MgATP-dependent Exocytosis

1989 • 209 citations

Gelsolin-Polyphosphoinositide Interaction

1989 • 200 citations

Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells

1986 • 183 citations

Conformational change and localization of calpactin I complex involved in exocytosis as revealed by quick-freeze, deep-etch electron microscopy and immunocytochemistry.

1990 • 179 citations

Biochemistry of Interorganelle Transport

1989 • 176 citations

Effects of phorbol ester on catecholamine secretion and protein phosphorylation in adrenal medullary cell cultures.

1985 • 170 citations

Presence of three pertussis toxin substrates and G_oα immunoreactivity in both plasma and granule membranes of chromaffin cells

1987 • 138 citations

Association of actin and myosin with secretory granule membranes

1975 • 137 citations

Effects of phorbol esters, diglyceride, and cholinergic agonists on the subcellular distribution of protein kinase C in intact or digitonin-permeabilized adrenal chromaffin cells.

1986 • 134 citations

Isolated Light Chains of Botulinum Neurotoxins Inhibit Exocytosis

1989 • 132 citations

Cholinergic Stimulation of Inositol Phosphate Formation in Bovine Adrenal Chromaffin Cells: Distinct Nicotinic and Muscarinic Mechanisms

1987 • 132 citations

Guanine nucleotide effects on catecholamine secretion from digitonin-permeabilized adrenal chromaffin cells.

1986 • 131 citations

The tetanus toxin light chain inhibits exocytosis

1989 • 129 citations

Redistribution of synaptophysin and synapsin I during alpha-latrotoxin-induced release of neurotransmitter at the neuromuscular junction.

1990 • 122 citations

Ca2+ influx causes rapid translocation of protein kinase C to membranes. Studies of the effects of secretagogues in adrenal chromaffin cells.

1988 • 115 citations

Requirement for GTP hydrolysis in the formation of secretory vesicles

1990 • 108 citations

Guanine nucleotides and Ca‐dependent exocytosis

1985 • 102 citations

Chromaffin granule membrane–F-actin interactions are calcium sensitive

1982 • 97 citations

Inhibition of exocytosis in bovine adrenal medullary cells by botulinum toxin type D

1985 • 96 citations

Distinct sites of action of clostridial neurotoxins revealed by double-poisoning of mouse motor nerve terminals

1987 • 95 citations

Phosphatidylinositol kinase. A component of the chromaffin-granule membrane

1973 • 91 citations

Evidence implicating protein kinase C in exocytosis from electropermeabilized bovine chromaffin cells

1988 • 89 citations

Activation of protein kinase C is not required for exocytosis from bovine adrenal chromaffin cells. The effects of protein kinase C(19-31), Ca/CaM kinase II(291-317), and staurosporine.

1990 • 87 citations

Microinjection of calmodulin antibodies into cultured chromaffin cells blocks catecholamine release in response to stimulation

1985 • 84 citations

Effects of Tetanus Toxin on Catecholamine Release from Intact and Digitonin‐Permeabilized Chromaffin Cells

1988 • 83 citations

Characterization of protein kinase C and its role in catecholamine secretion from bovine adrenal-medullary cells

1985 • 80 citations

Characterization of the solubilized and reconstituted ATP-dependent vesicular glutamate uptake system

1989 • 72 citations

Low molecular mass GTP‐binding proteins of adrenal chromaffin cells are present on the secretory granule

1989 • 71 citations

Isolated Light Chain of Tetanus Toxin Inhibits Exocytosis: Studies in Digitonin‐Permeabilized Cells

1989 • 61 citations

Protien phosphorylation and the dependence on Ca2+ and GTP-γ-S for exocytosis from permeabilised mast cells

1989 • 59 citations

A reassessment of Guanine Nucleotide Effects on Catecholamine Secretion from Permeabilized Adrenal Chromaffin cells

1989 • 58 citations

Reductive chain separation of botulinum A toxin — a prerequisite to its inhibitory action on exocytosis in chromaffin cells

1989 • 58 citations

Calpactins: Calcium‐regulated membrane‐skeletal proteins

1987 • 48 citations

Association of actin with chromaffin granule membranes and the effect of cytochalasin B on the polarity of actin filament elongation

1981 • 47 citations

The stimulatory effect of calpactin (annexin II) on calcium-dependent exocytosis in chromaffin cells: Requirement for both the N-terminal and core domains of p36 and ATP

1990 • 45 citations

Botulinum toxin‐induced ADP‐ribosylation and inhibition of exocytosis are unrelated events

1988 • 45 citations

Calcium- and guanine-nucleotide-dependent exocytosis in permeabilized rat mast cells. Modulation by protein kinase C

1990 • 39 citations

ATP-dependent and ATP-independent pathways of exocytosis revealed by interchanging glutamate and chloride as the major anion in permeabilized mast cells.

1990 • 39 citations

Stimulation of Ca2+-independent catecholamine secretion from digitonin-permeabilized bovine adrenal chromaffin cells by guanine nucleotide analogues. Relationship to arachidonate release

1990 • 39 citations

Low molecular weight GTP-binding proteins are associated with neuronal organelles involved in rapid axonal transport and exocytosis

1989 • 30 citations

Identification of an actively phosphorylated component of adrenal medulla chromaffin granules

1971 • 30 citations

ATPASE AND PHOSPHATIDYLINOSITOL KINASE ACTIVITIES OF ADRENAL CHROMAFFIN VESICLES

1975 • 28 citations

Hydrolysis‐Resistant GTP Analogs Stimulate Catecholamine Release from Digitonin‐Permeabilized PC12 Cells

1990 • 23 citations