Biochemistry of Interorganelle Transport

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

1980 • 1,808 citations

The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex

1986 • 1,175 citations

BIOSYNTHETIC PROTEIN TRANSPORT AND SORTING BY THE ENDOPLASMIC RETICULUM AND GOLGI

1987 • 985 citations

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

1986 • 896 citations

A ras-like protein is required for a post-Golgi event in yeast secretion

1987 • 894 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

1984 • 689 citations

Microtubules and the endoplasmic reticulum are highly interdependent structures.

1986 • 633 citations

G protein involvement in receptor-effector coupling.

1988 • 618 citations

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

1988 • 592 citations

Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum.

1989 • 581 citations

Do GTPases direct membrane traffic in secretion?

1988 • 540 citations

The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family

1989 • 535 citations

Pre- and post-golgi vacuoles operate in the transport of semliki forest virus membrane glycoproteins to the cell surface

1984 • 523 citations

Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport.

1988 • 519 citations

Phenotypic analysis of temperature-sensitive yeast actin mutants

1985 • 512 citations

Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum

1989 • 499 citations

Translocation and clustering of endosomes and lysosomes depends on microtubules.

1987 • 498 citations

Involvement of GTP-binding “G” proteins in transport through the Golgi stack

1987 • 495 citations

Dynamic behavior of endoplasmic reticulum in living cells

1988 • 471 citations

A new type of coated vesicular carrier that appears not to contain clathrin: Its possible role in protein transport within the Golgi stack

1986 • 462 citations

Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment.

1988 • 434 citations

Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack

1989 • 432 citations

Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack

1988 • 389 citations

The Human Rab Genes Encode a Family of GTP-binding Proteins Related to Yeast YPT1 and SEC4 Products Involved in Secretion

1989 • 387 citations

Receptors compete for adaptors found in plasma membrane coated pits.

1988 • 366 citations

The microtubule-dependent formation of a tubulovesicular network with characteristics of the ER from cultured cell extracts

1988 • 359 citations

Calcium and GTP: essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus.

1989 • 351 citations

Reconstitution of SEC gene product-dependent intercompartmental protein transport

1988 • 332 citations

Semi-intact cells permeable to macromolecules: Use in reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex

1987 • 321 citations

Purification of microsomal signal peptidase as a complex.

1986 • 313 citations

Associations of elements of the Golgi apparatus with microtubules.

1984 • 291 citations

Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein

1989 • 288 citations

Role for adenosine triphosphate in regulating the assembly and transport of vesicular stomatitis virus G protein trimers.

1987 • 286 citations

The ras-related YPT1 gene product in yeast: A GTP-binding protein that might be involved in microtubule organization

1986 • 281 citations

Protein-Mediated Membrane Fusion

1989 • 279 citations

Dissection of a single round of vesicular transport: Sequential intermediates for intercisternal movement in the Golgi stack

1989 • 269 citations

Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport

1989 • 250 citations

Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium

1988 • 243 citations

Mitotic Golgi fragments in HeLa cells and their role in the reassembly pathway.

1989 • 242 citations

A microtubule-binding protein associated with membranes of the Golgi apparatus.

1986 • 234 citations

Sequential intermediates in the pathway of intercompartmental transport in a cell-free system

1984 • 211 citations

Structural and functional properties of ras proteins

1989 • 211 citations

Differential effects of mutations in three domains on folding, quaternary structure, and intracellular transport of vesicular stomatitis virus G protein.

1988 • 210 citations

The dynamic nature of the Golgi complex.

1989 • 210 citations

A Test of Clathrin Function in Protein Secretion and Cell Growth

1985 • 202 citations

Site of addition of N-acetyl-galactosamine to the E1 glycoprotein of mouse hepatitis virus-A59.

1988 • 188 citations

Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells.

1987 • 188 citations

Binding of an N-ethylmaleimide-sensitive fusion protein to Golgi membranes requires both a soluble protein(s) and an integral membrane receptor.

1989 • 184 citations

Protein sorting by selective retention in the endoplasmic reticulum and Golgi stack

1987 • 179 citations

Dissection of Semliki Forest virus glycoprotein delivery from the trans-Golgi network to the cell surface in permeabilized BHK cells.

1988 • 178 citations

Reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex in yeast: the acceptor Golgi compartment is defective in the sec23 mutant.

1988 • 172 citations

Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment.

1988 • 139 citations

Perforated MDCK cells support intracellular transport.

1987 • 129 citations

Yeast Sec23p acts in the cytoplasm to promote protein transport from the endoplasmic reticulum to the Golgi complex in vivo and in vitro.

1989 • 128 citations

Characterization of new mutants in the early part of the yeast secretory pathway isolated by a [3H]mannose suicide selection.

1987 • 127 citations

Control of exocytosis

1987 • 98 citations

In vitro reconstitution of exocytosis from plasma membrane and isolated secretory vesicles.

1985 • 86 citations

Enzymes for Microtubule-dependent Motility

1989 • 82 citations

Transport of the vesicular stomatitis glycoprotein to trans Golgi membranes in a cell-free system.

1987 • 65 citations

Calcium-dependent Regulation of Chromaffin Granule Movement, Membrane Contact, and Fusion during Exocytosis

1982 • 60 citations

A novel prefusion complex formed during protein transport between Golgi cisternae in a cell-free system.

1986 • 49 citations

Components responsible for transport between successive Golgi cisternae are highly conserved in evolution.

1986 • 18 citations

Who will see a nearby supernova?

1989 • 14 citations