The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer

High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier

1989 • 2,140 citations

Mammalian Ras interacts directly with the serine/threonine kinase raf

1993 • 1,983 citations

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest.

1991 • 1,489 citations

Coiled coils: new structures and new functions

1996 • 1,196 citations

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

1998 • 1,101 citations

rab5 controls early endosome fusion in vitro

1991 • 1,090 citations

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

1994 • 948 citations

EEA1, an Early Endosome-Associated Protein.

1995 • 706 citations

A Novel Rab5 GDP/GTP Exchange Factor Complexed to Rabaptin-5 Links Nucleotide Exchange to Effector Recruitment and Function

1997 • 586 citations

Phosphatidylinositol(3)-Phosphate Signaling Mediated by Specific Binding to RING FYVE Domains

1998 • 497 citations

Endosomal Localization of the Autoantigen EEA1 Is Mediated by a Zinc-binding FYVE Finger

1996 • 480 citations

Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins

1998 • 370 citations

Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin

1996 • 290 citations

Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.

1995 • 262 citations

Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.

1995 • 255 citations

Assembly of the ER to Golgi SNARE complex requires Uso1p.

1996 • 203 citations

p115 is a general vesicular transport factor related to the yeast endoplasmic reticulum to Golgi transport factor Uso1p.

1995 • 199 citations

Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro.

1996 • 156 citations

Regulatory Role for GTP-Binding Proteins in Endocytosis

1989 • 138 citations

Phosphatidylinositol 3-kinase activity is required for early endosome fusion

1995 • 119 citations

Evidence for a Symmetrical Requirement for Rab5-GTP in in Vitro Endosome-Endosome Fusion

1998 • 75 citations

Cleavage of Rabaptin-5 blocks endosome fusion during apoptosis

1997 • 73 citations

Purification and characterization of yeast RNA polymerase II general initiation factor g

1992 • 57 citations