Interleukin (IL)‐11‐mediated Signal Transductiona

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Oncogenes and signal transduction

1991 • 2,816 citations

Cytokine signal transduction

1994 • 1,358 citations

Signal transduction via the MAP kinases: proceed at your own RSK.

1993 • 1,262 citations

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1993 • 1,223 citations

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

1993 • 1,169 citations

PRIMARY RESPONSE GENES INDUCED BY GROWTH FACTORS AND TUMOR PROMOTERS

1991 • 1,078 citations

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1993 • 988 citations

Association and Activation of Jak-Tyk Kinases by CNTF-LIF-OSM-IL-6 β Receptor Components

1994 • 972 citations

The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor

1992 • 897 citations

Association of Transcription Factor APRF and Protein Kinase Jak1 with the Interleukin-6 Signal Transducer gp130

1994 • 822 citations

The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction

1993 • 766 citations

CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130

1992 • 693 citations

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine.

1990 • 649 citations

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-& gamma; signal transduction pathway

1993 • 548 citations

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

1993 • 516 citations

Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors

1994 • 359 citations

Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter

1993 • 306 citations

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.

1994 • 304 citations

Involvement of IL-6 signal transducer gp130 in IL-11-mediated signal transduction.

1993 • 267 citations

The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase.

1993 • 203 citations

Leukemia Inhibitory Factor and Interleukin-6 Trigger the Same Immediate Early Response, Including Tyrosine Phosphorylation, upon Induction of Myeloid Leukemia Differentiation

1991 • 186 citations

Functional and biochemical association of Hck with the LIF/IL-6 receptor signal transducing subunit gp130 in embryonic stem cells.

1994 • 162 citations

Recombinant human interleukin-11 stimulates megakaryocytopoiesis and increases peripheral platelets in normal and splenectomized mice

1993 • 162 citations

Interleukin-6 signals activating junB and TIS11 gene transcription in a B-cell hybridoma.

1991 • 147 citations

Interleukin-6 signal transducer gp130 mediates oncostatin M signaling.

1992 • 147 citations

Effects of recombinant human interleukin-11 on hematopoietic reconstitution in transplant mice: acceleration of recovery of peripheral blood neutrophils and platelets

1993 • 139 citations

Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells.

1994 • 105 citations

Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation.

1991 • 95 citations

Genomic sequence and chromosomal location of human interleukin-11 gene (IL11)

1992 • 86 citations

Expression and Interactions of the Src Family of Tyrosine Protein Kinases in T Lymphocytes

1991 • 83 citations

Characterization of interleukin-11 receptor and protein tyrosine phosphorylation induced by interleukin-11 in mouse 3T3-L1 cells.

1992 • 69 citations

The SCL gene product is regulated by and differentially regulates cytokine responses during myeloid leukemic cell differentiation.

1993 • 53 citations

Interleukin 11: An overview

1993 • 53 citations

Identification of a 130-kilodalton tyrosine-phosphorylated protein induced by interleukin-11 as JAK2 tyrosine kinase, which associates with gp130 signal transducer.

1994 • 52 citations

Regulation of interleukin (IL)-11 gene expression in IL-1 induced primate bone marrow stromal cells

1994 • 48 citations

Interleukin-11 induces phosphatidic acid formation and activates map kinase in mouse 3T3-L1 cells

1995 • 35 citations

Protein tyrosine phosphorylation and activation of primary response genes by interleukin 11 in B9-TY1 cells.

1993 • 18 citations

Interleukin-11 Mediated Signal Transduction Pathways: Comparison With Those of Interleukin-6

1993 • 5 citations