IGF-I, GH, and Sex Steroid Effects in Normal Mammary Gland Development

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

1995 • 1,834 citations

Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice.

1959 • 985 citations

Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development

1999 • 551 citations

A paracrine role for the epithelial progesterone receptor in mammary gland development

1998 • 452 citations

GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

1993 • 399 citations

An atlas of mouse mammary gland development.

2000 • 398 citations

The Mammary gland : development, regulation, and function

1987 • 396 citations

Amphiregulin is an essential mediator of estrogen receptor α function in mammary gland development

2007 • 301 citations

Endocrine Control of Mammary-Gland Development and Function in the C3H/He Crgl Mouse<xref ref-type="fn" rid="FN1">2</xref>

1958 • 281 citations

The hormonal control of mammary growth and lactation.

1958 • 267 citations

Postnatal Development of the Rodent Mammary Gland

1987 • 266 citations

Insulin-Like Growth Factor I Is Essential for Terminal End Bud Formation and Ductal Morphogenesis during Mammary Development1

1999 • 226 citations

The mammary gland

1991 • 216 citations

Hypophyseal Growth Hormone, Nature and Actions

1955 • 208 citations

ISOLATION AND PROPERTIES OF THE ANTERIOR HYPOPHYSEAL GROWTH HORMONE

1945 • 205 citations

Key stages in mammary gland development: The mammary end bud as a motile organ

2005 • 204 citations

Development of the Human Mammary Gland

1987 • 199 citations

Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice.

1990 • 196 citations

The Ames Dwarf Gene Is Required for Pit-1 Gene Activation

1995 • 174 citations

TGF-β1-induced inhibition of mouse mammary ductal growth: Developmental specificity and characterization

1989 • 174 citations

IGF-I: an essential factor in terminal end bud formation and ductal morphogenesis.

2000 • 171 citations

Postnatal mammary gland morphogenesis

2001 • 165 citations

Growth Hormone and Insulin-Like Growth Factor-I in the Transition from Normal Mammary Development to Preneoplastic Mammary Lesions

2008 • 150 citations

Activation and function of the epidermal growth factor receptor and erbB-2 during mammary gland morphogenesis.

1998 • 145 citations

Targeted Disruption of the IGF-I Receptor Gene Decreases Cellular Proliferation in Mammary Terminal End Buds

2001 • 129 citations

Evidence That the Mammary Fat Pad Mediates the Action of Growth Hormone in Mammary Gland Development

1998 • 119 citations

Intact and amino-terminally shortened forms of insulin-like growth factor I induce mammary gland differentiation and development.

1992 • 114 citations

The hormone of the ovarian follicle; its localization and action in test animals, and additional points bearing upon the internal secretion of the ovary

1924 • 112 citations

Evidence that the growth hormone receptor mediates differentiation and development of the mammary gland.

1993 • 110 citations

Alveolar and Lactogenic Differentiation

2006 • 106 citations

NON-LACTOGENIC EFFECTS OF GROWTH HORMONE ON GROWTH AND INSULIN-LIKE GROWTH FACTOR-I MESSENGER RIBONUCLEIC ACID OF RAT MAMMARY GLAND

1990 • 105 citations

A comparison of the biological activity of the recombinant intact and truncated insulin-like growth factor 1 (IGF-1)

1989 • 101 citations

The hypophyseal growth hormone, nature and actions

1955 • 96 citations

Mammary Gland Branching Morphogenesis Is Diminished in Mice with a Deficiency of Insulin-like Growth Factor-I (IGF-I), But Not in Mice with a Liver-Specific Deletion of IGF-I

2004 • 89 citations

Progesterone Stimulates Mammary Gland Ductal Morphogenesis by Synergizing with and Enhancing Insulin-Like Growth Factor-I Action

2004 • 88 citations

The Insulin-Like Growth Factors (IGF) and IGF Type I Receptor during Postnatal Growth of the Murine Mammary Gland: Sites of Messenger Ribonucleic Acid Expression and Potential Functions**This work was supported, in part, by NIH Grant DK-48103 (to T.L.W.)

1999 • 86 citations

The role of mammary stroma in modulating the proliferative response to ovarian hormones in the normal mammary gland.

1998 • 83 citations

Growth Hormone and Prolactin Synthesis in Normal and Homozygous Snell and Ames Dwarf Mice*

1981 • 83 citations

The insulin-like growth factors (IGFs) and IGF binding proteins in postnatal development of murine mammary glands.

2000 • 82 citations

The role of TGF-β in patterning and growth of the mammary ductal tree

1996 • 81 citations

Insulin-like growth factor binding proteins: IGF-dependent and -independent effects in the mammary gland.

2000 • 73 citations

Genetic Manipulation of the IGF-I Axis to Regulate Mammary Gland Development and Function

2002 • 64 citations

Requirement for IGF-I in Epidermal Growth Factor-Mediated Cell Cycle Progression of Mammary Epithelial Cells

2002 • 54 citations

Epithelial-Specific and Stage-Specific Functions of Insulin-Like Growth Factor-I during Postnatal Mammary Development

2006 • 54 citations

Does an IGF-binding protein (IGFBP) present in involuting rat mammary gland regulate apoptosis?

1995 • 48 citations

Isolation of Pituitary Follicle-Stimulating Hormone (FSH)

1949 • 47 citations

Developmental and Hormonal Signals Dramatically Alter the Localization and Abundance of Insulin Receptor Substrate Proteins in the Mammary Gland

2003 • 47 citations

Mammary Gland Development in the Hypophysectomized Albino Rat.

1936 • 43 citations

Primate mammary development. Effects of hypophysectomy, prolactin inhibition, and growth hormone administration.

1985 • 41 citations

Influence of Hypothalamus and Ovary on Pituitary Function in Transgenic Mice Expressing the Bovine Growth Hormone Gene and in Growth Hormone-Deficient Ames Dwarf Mice1

1996 • 39 citations

SOM230 Inhibits Insulin-Like Growth Factor-I Action in Mammary Gland Development by Pituitary Independent Mechanism: Mediated through Somatostatin Subtype Receptor 3?

2005 • 39 citations

Growth Factor Regulation of Cell Cycle Progression in Mammary Epithelial Cells

2004 • 39 citations

Estrogen-triggered delays in mammary gland gene expression during the estrous cycle: evidence for a novel timing system

2006 • 38 citations

Programmed cell death in the terminal endbud.

1999 • 38 citations

The Transforming Growth Factors Beta in Development and Functional Differentiation of the Mouse Mammary Gland

2001 • 37 citations

The effect of GH on estrogen receptor expression in the rat mammary gland

1999 • 37 citations

Mammary Growth in Hypophysectomized Male Mice Receiving Estrogen and Prolactin.

1941 • 31 citations

Effects of Estrone and Progesterone on Male Rabbit Mammary Glands. I. Varying Doses of Progesterone

1941 • 28 citations

Some characteristics of the preneoplastic hyperplastic alveolar nodules of C3H/Crgl mice.

1961 • 25 citations

Progesterone stimulates DNA synthesis and lobulo-alveolar development in mammary glands in ovariectomized mice

1999 • 22 citations

Non-Effect of Estrogenic Hormones on Mammary Gland of Hypophysectomized Guinea Pig.

1936 • 19 citations

Endocrine control of mammary glands in C3H mice.

1956 • 17 citations

FAILURE OF STEROID HORMONES TO INDUCE MAMMARY GROWTH IN HYPOPHYSECTOMI2ED RATS

1942 • 16 citations

Growth and adrenocorticotropic hormones of anterior pituitary.

1950 • 12 citations

Isolated deficiency of immunocytochemically detected somatostatin in Snell dwarf, but not in “little,” mice

1987 • 9 citations

The effect of the ovarian hormones theelin and corporin upon the growth of the mammary gland of the rabbit

1932 • 7 citations