Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis

Caspases: Enemies Within

1998 • 6,923 citations

Caspases: the executioners of apoptosis

1997 • 4,674 citations

Apoptosis, oncosis, and necrosis. An overview of cell death.

1995 • 3,325 citations

Current protocols in immunology

1992 • 1,464 citations

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

1999 • 887 citations

Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor

1998 • 887 citations

Distinct Caspase Cascades Are Initiated in Receptor-mediated and Chemical-induced Apoptosis

1999 • 829 citations

Biochemical Characteristics of Caspases-3, -6, -7, and -8

1997 • 536 citations

The Molecular Effects of Acrolein

2000 • 514 citations

Intracellular ATP, a switch in the decision between apoptosis and necrosis

1998 • 353 citations

Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-κB

2001 • 316 citations

High performance liquid chromatography: a rapid isocratic method for determination of creatine compounds and adenine nucleotides in myocardial tissue

1986 • 294 citations

Current Status of Acrolein as a Lipid Peroxidation Product

1999 • 288 citations

Cell death induced by topoisomerase-targeted drugs: more questions than answers

1998 • 280 citations

A critical review of the literature on acrolein toxicity

1985 • 277 citations

The Nomenclature of Cell Death: Recommendations of an ad hoc Committee of the Society of Toxicologic Pathologists

1999 • 236 citations

Constitutive production of a unique lymphokine (IL 3) by the WEHI-3 cell line.

1982 • 227 citations

Inhibition of caspase activity induces a switch from apoptosis to necrosis

1998 • 189 citations

Distinct Pathways for Stimulation of Cytochrome cRelease by Etoposide

2000 • 155 citations

The chemistry of the metabolites of cyclophosphamide.

1999 • 154 citations

The Chemistry of the Metabolites of Cyclophosphamide

1999 • 146 citations

The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.

2000 • 133 citations

Inhibition of neutrophil apoptosis by acrolein: a mechanism of tobacco-related lung disease?

2001 • 109 citations

The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP

1999 • 92 citations

Acrolein Causes Inhibitor κB-independent Decreases in Nuclear Factor κB Activation in Human Lung Adenocarcinoma (A549) Cells

1999 • 91 citations

Detection and quantification of live, apoptotic, and necrotic human peripheral lymphocytes by single-laser flow cytometry

1995 • 79 citations

Poly(ADP-Ribose) Polymerase Inhibition in Oxidant-Stressed Endothelial Cells Prevents Oncosis and Permits Caspase Activation and Apoptosis

1999 • 75 citations

Binding of Annexin V to Membrane Products of Lipid Peroxidation

2001 • 69 citations

TNFα-Induced IEC-6 Cell Apoptosis Requires Activation of ICE Caspases whereas Complete Inhibition of the Caspase Cascade Leads to Necrotic Cell Death

1999 • 68 citations

Relationships between cell density, glutathione and proliferation of A549 human lung adenocarcinoma cells treated with acrolein

1997 • 62 citations

Apoptosis in hematopoietic cells (FL5.12) caused by interleukin-3 withdrawal: relationship to caspase activity and the loss of glutathione

1999 • 58 citations

Involvement of caspases in 4-hydroxy-alkenal–induced apoptosis in human leukemic cells

2001 • 52 citations

Acrolein cytotoxicity and glutathione depletion in n-3 fatty acid sensitive- and resistant human tumor cells.

1999 • 36 citations

4-Hydroxynonenal, an end-product of lipid peroxidation, induces apoptosis in human leukemic T- and B-cell lines

2000 • 32 citations

Bcl-xLOverexpression Restricts Heat-Induced Apoptosis and Influences hsp70, bcl-2, and Bax Protein Levels in FL5.12 Cells

1997 • 29 citations

IL-4 inhibits apoptosis and prevents mitochondrial damage without inducing the switch to necrosis observed with caspase inhibitors

1999 • 25 citations